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Physician-Scientist DevelopmentIn-Press Preview Open Access | 10.1172/jci.insight.208965

Predoctoral grant writing among physician-scientist trainees: A national survey of barriers and facilitators of success

Brian J. Thomas,1 Tiger S. Zhang,2 Daniel C. Brock,3 Timothy J. Ley,4 William D. Arnold,5 and Cynthia Y. Tang6

1University of Missouri School of Medicine, Columbia, United States of America

2University of North Carolina School of Medicine, United States of America

3Baylor College of Medicine, United States of America

4Division of Oncology, Washington University, St. Louis, United States of America

5Department of Physical Medicine and Rehabilitation, University of Missouri School of Medicine, Columbia, United States of America

6Department of Anesthesiology, Duke University Medical Center, Durham, United States of America

Find articles by Thomas, B. in: PubMed | Google Scholar

1University of Missouri School of Medicine, Columbia, United States of America

2University of North Carolina School of Medicine, United States of America

3Baylor College of Medicine, United States of America

4Division of Oncology, Washington University, St. Louis, United States of America

5Department of Physical Medicine and Rehabilitation, University of Missouri School of Medicine, Columbia, United States of America

6Department of Anesthesiology, Duke University Medical Center, Durham, United States of America

Find articles by Zhang, T. in: PubMed | Google Scholar

1University of Missouri School of Medicine, Columbia, United States of America

2University of North Carolina School of Medicine, United States of America

3Baylor College of Medicine, United States of America

4Division of Oncology, Washington University, St. Louis, United States of America

5Department of Physical Medicine and Rehabilitation, University of Missouri School of Medicine, Columbia, United States of America

6Department of Anesthesiology, Duke University Medical Center, Durham, United States of America

Find articles by Brock, D. in: PubMed | Google Scholar

1University of Missouri School of Medicine, Columbia, United States of America

2University of North Carolina School of Medicine, United States of America

3Baylor College of Medicine, United States of America

4Division of Oncology, Washington University, St. Louis, United States of America

5Department of Physical Medicine and Rehabilitation, University of Missouri School of Medicine, Columbia, United States of America

6Department of Anesthesiology, Duke University Medical Center, Durham, United States of America

Find articles by Ley, T. in: PubMed | Google Scholar |

1University of Missouri School of Medicine, Columbia, United States of America

2University of North Carolina School of Medicine, United States of America

3Baylor College of Medicine, United States of America

4Division of Oncology, Washington University, St. Louis, United States of America

5Department of Physical Medicine and Rehabilitation, University of Missouri School of Medicine, Columbia, United States of America

6Department of Anesthesiology, Duke University Medical Center, Durham, United States of America

Find articles by Arnold, W. in: PubMed | Google Scholar

1University of Missouri School of Medicine, Columbia, United States of America

2University of North Carolina School of Medicine, United States of America

3Baylor College of Medicine, United States of America

4Division of Oncology, Washington University, St. Louis, United States of America

5Department of Physical Medicine and Rehabilitation, University of Missouri School of Medicine, Columbia, United States of America

6Department of Anesthesiology, Duke University Medical Center, Durham, United States of America

Find articles by Tang, C. in: PubMed | Google Scholar

Published September 1, 2026 - More info

JCI Insight. https://doi.org/10.1172/jci.insight.208965.
Copyright © 2026, Thomas et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Published September 1, 2026 - Version history
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Abstract

Effective grant writing is an essential skill for physician-scientists to achieve academic independence and long-term career success. Previous studies have established that receiving an NIH F30 or F31 during predoctoral training is correlated with success in subsequent training stages and contributes to the retention of physician-scientists in academia. However, many trainees experience challenges in predoctoral grant writing that prevent them from submitting a grant or developing a well-rounded application. Identifying and addressing these challenges remains crucial; however, limitations in NIH public reporting exclude data on prospective applicants and applicants who were not awarded grants. In this study, we employed a national survey of trainees to identify perceived needs and barriers to grant writing as well as factors associated with NIH predoctoral grant funding success. We found that limited mentor and sponsor support to developing quality applications, constrained eligibility timelines, and limited available awards were prominent barriers to submission, while access to previously funded applications was the most valued resource among respondents. Using these findings, we highlight opportunities for interventions at the federal, institutional, applicant, and medical and scientific society levels to improve predoctoral grant writing feasibility and success.

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