TRPA1 activation assists topical rosemary extract in enhancing skin repair

In this episode, Emmanuel Rapp and Jiayi Pang explain their findings that suggest that topical rosemary extract may represent an effective and accessible therapeutic approach to improve skin repair outcomes.

Pathways for monovalent and divalent cation transport and distinct cell types

In this episode, David Ellison, Sebastian Bachman, and Jessica Bahena-Lopez describe how their results show that there are three cell types along the kidney thick ascending limb, enabling it to adjust solute absorption selectively to maintain homeostasis.

Breast cancer immunotherapy is enhanced by the gut microbiome following bariatric surgery

In this episode, Liza Makowski explains that bariatric surgery causes long term changes to our gut microbiome, which the study demonstrates could improve the body’s immune response to current breast cancer treatments.

Bone growth promotion in two FGFR3-driven models of chondrodysplasia

In this episode, Jacqueline Starrett and Will Charlton describe how TYRA-300, an FGFR3-selective kinase inhibitor, increases bone growth in mouse models of achondroplasia and hypochondroplasia.

The authors thank Rob Wishnowsky of Cruxio, Inc., and Fernando de Miguel for support creating the video abstract.

Response to immunotherapy in metastatic urothelial cancer and multimodal integration of blood

In this episode, Davide Croci, Sandra van Wilpe, and Niven Mehra explain that their manuscript predicts clinical benefit to immunotherapy by analyzing combined biomarkers from circulating tumor DNA and immune cell gene expression data in blood.