ResearchIn-Press PreviewMetabolismNephrology
Open Access | 
10.1172/jci.insight.191458
PRDM16 acts as a therapeutic downstream target of TGF-β signaling in chronic kidney disease
Qian Yuan,1 Ben Tang,1 Yuting Zhu,1 Chao Wan,2 Yaru Xie,1 Yajuan Xie,1 Cheng Wan,1 Hua Su,1 Youhua Liu,3 and Chun Zhang4
1Department of Nephrology, Huazhong University of Science and Technology, Wuhan, China
2Cancer Center, Huazhong University of Science and Technology, Wuhan, China
3Division of Nephrology, Southern Medical University, Guangzhou, China
4Department of Nephrology, Union Hospital,Huazhong University of Science and Technology Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Find articles by Yuan, Q. in: PubMed | Google Scholar
1Department of Nephrology, Huazhong University of Science and Technology, Wuhan, China
2Cancer Center, Huazhong University of Science and Technology, Wuhan, China
3Division of Nephrology, Southern Medical University, Guangzhou, China
4Department of Nephrology, Union Hospital,Huazhong University of Science and Technology Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Find articles by Tang, B. in: PubMed | Google Scholar
1Department of Nephrology, Huazhong University of Science and Technology, Wuhan, China
2Cancer Center, Huazhong University of Science and Technology, Wuhan, China
3Division of Nephrology, Southern Medical University, Guangzhou, China
4Department of Nephrology, Union Hospital,Huazhong University of Science and Technology Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Find articles by Zhu, Y. in: PubMed | Google Scholar
1Department of Nephrology, Huazhong University of Science and Technology, Wuhan, China
2Cancer Center, Huazhong University of Science and Technology, Wuhan, China
3Division of Nephrology, Southern Medical University, Guangzhou, China
4Department of Nephrology, Union Hospital,Huazhong University of Science and Technology Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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Wan, C.
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1Department of Nephrology, Huazhong University of Science and Technology, Wuhan, China
2Cancer Center, Huazhong University of Science and Technology, Wuhan, China
3Division of Nephrology, Southern Medical University, Guangzhou, China
4Department of Nephrology, Union Hospital,Huazhong University of Science and Technology Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Find articles by Xie, Y. in: PubMed | Google Scholar
1Department of Nephrology, Huazhong University of Science and Technology, Wuhan, China
2Cancer Center, Huazhong University of Science and Technology, Wuhan, China
3Division of Nephrology, Southern Medical University, Guangzhou, China
4Department of Nephrology, Union Hospital,Huazhong University of Science and Technology Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Find articles by Xie, Y. in: PubMed | Google Scholar
1Department of Nephrology, Huazhong University of Science and Technology, Wuhan, China
2Cancer Center, Huazhong University of Science and Technology, Wuhan, China
3Division of Nephrology, Southern Medical University, Guangzhou, China
4Department of Nephrology, Union Hospital,Huazhong University of Science and Technology Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Find articles by Wan, C. in: PubMed | Google Scholar
1Department of Nephrology, Huazhong University of Science and Technology, Wuhan, China
2Cancer Center, Huazhong University of Science and Technology, Wuhan, China
3Division of Nephrology, Southern Medical University, Guangzhou, China
4Department of Nephrology, Union Hospital,Huazhong University of Science and Technology Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
Find articles by Su, H. in: PubMed | Google Scholar
1Department of Nephrology, Huazhong University of Science and Technology, Wuhan, China
2Cancer Center, Huazhong University of Science and Technology, Wuhan, China
3Division of Nephrology, Southern Medical University, Guangzhou, China
4Department of Nephrology, Union Hospital,Huazhong University of Science and Technology Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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Liu, Y.
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1Department of Nephrology, Huazhong University of Science and Technology, Wuhan, China
2Cancer Center, Huazhong University of Science and Technology, Wuhan, China
3Division of Nephrology, Southern Medical University, Guangzhou, China
4Department of Nephrology, Union Hospital,Huazhong University of Science and Technology Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
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Zhang, C.
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Published August 4, 2025 - More info
Copyright © 2025, Yuan et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
