ResearchIn-Press PreviewInflammationNeuroscience
Open Access | 
10.1172/jci.insight.181885
MSC transplantation ameliorates depression in lupus by suppressing Th1 cell-shaped synaptic stripping
Han Xiaojuan,1 Dandan Wang,1 Liang Chen,2 Hua Song,3 Xiulan Zheng,4 Xin Zhang,3 Shengnan Zhao,3 Jun Liang,3 Tianshu Xu,5 Zhibin Hu,6 and Lingyun Sun1
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Xiaojuan, H. in: JCI | PubMed | Google Scholar
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Wang, D. in: JCI | PubMed | Google Scholar
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Chen, L. in: JCI | PubMed | Google Scholar
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Song, H. in: JCI | PubMed | Google Scholar
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Zheng, X. in: JCI | PubMed | Google Scholar
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Zhang, X. in: JCI | PubMed | Google Scholar
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Zhao, S. in: JCI | PubMed | Google Scholar
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Liang, J. in: JCI | PubMed | Google Scholar
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Xu, T. in: JCI | PubMed | Google Scholar
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Hu, Z. in: JCI | PubMed | Google Scholar
1Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
2Department of Gynecology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
3Department of Rheumatology and Immunology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China
4School of Pharmacy, Macau University of Science and Technology, Macau, China
5Department of Traditional Chinese Medicine, Nanjing Drum Tower Hospital Clinical College of Nanjing University of Chinese Medicine, Nanjing, China
6State Key Laboratory of Reproductive Medicine and Offspring Health, Nanjing Medical University, Nanjing, China
Find articles by Sun, L. in: JCI | PubMed | Google Scholar
Published March 6, 2025 - More info
Copyright © 2025, Xiaojuan et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
