In this episode, Oded Volovelsky and colleagues report that rapamycin or dexamethasone administration in pregnancy to a mouse model of tuberous sclerosis complex disease prevents cystic kidney disease in offspring.
In this episode, Li Yang and colleagues discuss how hepatic CD71+ erythroid cells play an immunoregulatory role in biliary atresia by suppressing the activation of hepatic lymphocytes.
In this Episode, Adrian Vella and colleagues discuss abnormal insulin pulse characteristics in non-diabetic individuals are linked with diabetes-associated variation in TCF7L2 and may serve as early markers of β cell dysfunction.
In this episode, Krishnendu Roy, Rabindra Tirouvanziam, Amit Gaggar, and colleagues describe the development of a drug delivery platform that allows direct targeting of lung neutrophils under inflammatory conditions.
In this episode, Cate Speake and colleagues employ an analytical method that incorporates reproducibility testing to identify a composite signature prognostic for type 1 diabetes disease progression after diagnosis.