MD-PhD program admissions: application metrics and predicting outcomes

In this episode, Skip Brass and Myles Akabas explain how the results of their manuscript show that none of the applicant metrics, individually or collectively, predict in-program performance, future research effort, or eventual workplace choices even when comparisons were limited to those in the top and bottom quintiles.

Brain toxicity via kidney injury is potentially linked by quinolinic acid

In this Episode, Kumar Sharma and Afaf Saliba explain the potential link to kidney injury through brain toxicity due to quinolinic acid.

Gut inflammation in mice is alleviated by glucose-dependent insulinotropic polypeptide receptor

In this episode, Rola Hammoud explains that the paper demonstrates that activation versus loss of GIP action impacts the extent of experimental gut inflammation in mice.

The Women’s Health Initiative and lung cancer in never-smokers

In this episode, Sitapriya Moorthi explains that the genomic landscape of lung cancer in older never-smoker women has unique patterns of mutations but is indistinguishable in its copy number alterations from smokers.

Preserving kidney function with aldehyde dehydrogenase 2

In this episode, Hsiang-Tsui Wang explains that targeting the interaction between aldehyde dehydrogenase 2 and acrolein, a byproduct of lipid peroxidation, may offer a therapeutic strategy for chronic kidney disease (CKD).