Resource and Technical AdvanceIn-Press PreviewCell biologyInfectious diseaseInflammation
Open Access | 
10.1172/jci.insight.203042
Macrophages orchestrate antiviral defense and epithelial repair in a human iPSC-derived alveolar air-liquid interface
Declan L. Turner,1 Hannah Baric,1 Katelyn Patatsos,1 Sahel Amoozadeh,1 Michael See,1 Kathleen A. Strumila,1 Jack T. Murphy,1 Jeremy J. Wiyana,1 Liam Gubbels,1 Elizabeth S. Ng,1 Andrew G. Elefanty,1 Melanie R. Neeland,1 Shivanthan Shanthikumar,1 Sarah L. Londrigan,2 Mirana Ramialison,1 Fernando J. Rossello,1 Edouard G. Stanley,3 and Rhiannon B. Werder1
1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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1Murdoch Children's Research Institute, Melbourne, Australia
2Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Melbourne, Australia
3Murdoch Childrens Research Institute, Melbourne, Australia
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Published March 17, 2026 - More info
Copyright © 2026, Turner et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
