Perforin-2 is a highly conserved pore-forming protein encoded by macrophage expressed gene 1 (
Ryan M. McCormack, Eva P. Szymanski, Amy P. Hsu, Elena Perez, Kenneth N. Olivier, Eva Fisher, E. Brook Goodhew, Eckhard R. Podack, Steven M. Holland
MPEG1-mutated EBV-transformed B cells, neutrophils, and monocyte-derived macrophages have impaired control of MAC in vitro.