ResearchIn-Press PreviewMetabolismVascular biology
Open Access | 
10.1172/jci.insight.201311
BAT-derived miR-378a-3p facilitates endothelial angiogenic function and promotes wound healing
Hongyan Deng,1 Yuyu Xie,1 Jiadai Liu,1 Jing Ge,1 Qianqian Kang,2 Rui He,1 Zhihan Wang,1 Xuemin Peng,1 Zengzhe Zhu,1 Wenshe Wang,1 Yulian Liu,1 Ronghui Gao,1 Ruping Pan,2 Min Yang,3 and Yong Chen1
1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
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1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
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1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
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1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
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1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
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1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
Find articles by He, R. in: PubMed | Google Scholar
1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
Find articles by Wang, Z. in: PubMed | Google Scholar
1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
Find articles by Peng, X. in: PubMed | Google Scholar
1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
Find articles by Zhu, Z. in: PubMed | Google Scholar
1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
Find articles by Wang, W. in: PubMed | Google Scholar
1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
Find articles by Liu, Y. in: PubMed | Google Scholar
1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
Find articles by Gao, R. in: PubMed | Google Scholar
1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
Find articles by Pan, R. in: PubMed | Google Scholar
1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
Find articles by Yang, M. in: PubMed | Google Scholar
1Division of Endocrinology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College and State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Huazhong University of Science and Technology, Wuhan, China
2Laboratory of Endocrinology and Metabolism, Ministry of Education Key Laboratory of Vascular Aging, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Endocrinology, Fifth People's Hospital of Shanghai, Fudan University, Shanghai, China
Find articles by Chen, Y. in: PubMed | Google Scholar
Published April 21, 2026 - More info
Copyright © 2026, Deng et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
