ResearchIn-Press PreviewCell biologyOncology
Open Access | 
10.1172/jci.insight.186703
Lomitapide enhances cytotoxic effects of temozolomide in chemo-resistant glioblastoma
Alyona Ivanova,1 Taylor M. Wilson,1 Kimia Ghannad-Zadeh,1 Esmond Tse,1 Robert Flick,2 Megan Wu,1 and Sunit Das1
1The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, Canada
2Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada
3The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, United States of America
Find articles by Ivanova, A. in: PubMed | Google Scholar
1The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, Canada
2Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada
3The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, United States of America
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1The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, Canada
2Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada
3The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, United States of America
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1The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, Canada
2Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada
3The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, United States of America
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1The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, Canada
2Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada
3The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, United States of America
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1The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, Canada
2Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada
3The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, United States of America
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1The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, Canada
2Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada
3The Arthur and Sonia Labatt Brain Tumour Research Center, The Hospital for Sick Children, Toronto, United States of America
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Published July 23, 2025 - More info
Copyright © 2025, Ivanova et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
