ResearchIn-Press PreviewNephrology
Open Access | 
10.1172/jci.insight.182534
Organelle communication maintains mitochondrial and endosomal homeostasis during podocyte lipotoxicity
Sho Hasegawa,1 Masaomi Nangaku,2 Yuto Takenaka,1 Chigusa Kitayama,1 Qi Li,1 Madina Saipidin,1 Yu Ah Hong,1 Jin Shang,1 Yusuke Hirabayashi,5 Naoto Kubota,6 Takashi Kadowaki,6 and Reiko Inagi1
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Hasegawa, S. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Nangaku, M. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Takenaka, Y. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Kitayama, C. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Li, Q. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Saipidin, M. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Hong, Y. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Shang, J. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Hirabayashi, Y. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Kubota, N. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Kadowaki, T. in: JCI | PubMed | Google Scholar
1Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Japan
2Division of Nephrology and Endocrinology, The University of Tokyo School of Medicine, Tokyo, Japan
3Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, Korea, Republic of
4Division of Chronic Kidney Disease Pathophysiology, The University of Tokyo School of Medicine, Tokyo, China
5Department of Chemistry and Biotechnology, The University of Tokyo School of Engineering, Tokyo, Japan
6Department of Diabetes and Metabolic Diseases, The University of Tokyo School of Medicine, Tokyo, Japan
Find articles by Inagi, R. in: JCI | PubMed | Google Scholar
Published August 8, 2024 - More info
Copyright © 2024, Hasegawa et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
