ResearchIn-Press PreviewInflammation
Open Access | 
10.1172/jci.insight.159058
MEX3B inhibits collagen production in eosinophilic nasal polyps by downregulating epithelial cell TGFBR3 mRNA stability
Jin-Xin Liu,1 Chen Ao-Nan,1 Qihong Yu,2 Ke-Tai Shi,1 Yi-Bo Liu,1 Cui-Lian Guo,1 Zhe-Zheng Wang,1 Yin Yao,1 Li Pan,1 Xiang Lu,1 Kai Xu,1 Heng Wang,1 Ming Zeng,1 Chaohong Liu,3 Robert P. Schleimer,4 Ning Wu,5 Bo Liao,1 and Zheng Liu1
1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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Yu, Q.
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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Shi, K.
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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Xu, K.
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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Zeng, M.
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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1Department of Otolaryngology-Head and Neck Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
2Hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
3Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
4Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine Northwestern University, Chicago, United States of America
5Department of Otolaryngology-Head and Neck Surgery, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China
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Published March 28, 2023 - More info
Copyright © 2023, Liu et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
