In this video collection, authors of findings published in JCI Insight present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Author's Take Guidelines page.
In this episode, Dr. Ramani Ramchandran explains that, in this study, the authors show that cilia on endothelial cells can disassemble under shear stress, and proteins from cilia can be tracked in fluids as a result of the disassembly process.
In this episode, Ghazaleh Tabatabai and colleagues discuss the landscape of tissue metabolites and corresponding transcripts in diffuse glioma assessed by NMR metabolomics and RNA sequening.
In this episode, Nardhy Gomez-Lopez explains how single-cell RNA-sequencing reveals the contributions of specific myometrial cell types to the biological processes implicated in term parturition.
In this episode, Nardhy Gomez-Lopez explains that macrophages exert anti-inflammatory effects in late gestation, to maintain uterine quiescence and to protect against fetal inflammatory injury that compromises postnatal survival.
In this episode, Robert Blanton explains how this paper identifies mixed lineage kinase 3 as a novel PKG1a substrate. MLK3 mediates PKGI therapeutic effects on LV function but regulates blood pressure independently of PKG1.