In this video collection, authors of findings published in JCI Insight present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Author's Take Guidelines page.
In this episode, Cullen Taniguchi, Meifang Yu, Nicholas Nguyen, and colleagues demonstrate that enhancing mitochondrial fusion in pancreatic cancer cells induces mitophagy, which alters tumor energetics and correlates with improved survival in mouse models…
In this episode, Matthew Campbell, Natalie Hudson, and colleagues show that blood vessels of the inner retina are highly dynamic and that loss of inner blood-retina barrier integrity may underlie age-related macular degeneration.
In this episode, Annet Kirabo, Jane Ferguson, and colleagues provide evidence that high-salt diet-induced changes in the gut microbiome promote dendritic cell activation, leading to inflammation and hypertension.
In this episode, John Coffin, Stephen Hughes and colleagues show that clones of HIV-infected cells arise in the first few weeks following infection and can persist even in patients on successful anti-retroviral therapy.
In this episode, Singh and colleagues use Imaging mass cytometry to generate an atlas of the human kidney at a single-cell resolution.