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Author's Take

In this video collection, authors of findings published in JCI Insight present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Author's Take Guidelines page.

Aging and T cells during recovery from influenza pneumonia

The age-related pro-repair function of Treg cells following influenza infection is determined by cell-autonomous mechanisms.


Protection against iatrogenically induced hearing loss

In this episode, Marisa Zallocchi explains how treatment with quinoxaline derivatives protects from aminoglycoside- and cisplatin-hearing loss by NF-kB inhibition.


Epithelial IL-33 in chronic airway disease

In this episode, Jennifer Alexander-Brett and colleagues explain that epithelial IL-33 co-secretion with exosomes is blocked by inhibitors of the neutral sphingomyelinase-dependent multivesicular endosome pathway, which reduces type-2 inflammation in airway disease.


TRPV4 channels are essential for protection from lung edema

In this episode, Alexander Dietrich and Christian Schremmer explain how TRPV4 is essential for alveolar epithelial function and protects from ischemia-reperfusion induced lung edema.


Predicting atrial fibrillation after ablation

In this episode, Jasmeet Reyat, Winnie Chua, Larissa Fabritz, and colleagues explain that, building on genomic and experimental findings, low PITX2 in left atrial cardiomyocytes and high BMP10 in plasma predict recurrent AF in patients after ablation.

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