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Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma
Stephen M.F. Jamieson, … , Michael A. Curran, Francis W. Hunter
Stephen M.F. Jamieson, … , Michael A. Curran, Francis W. Hunter
Published February 22, 2023
Citation Information: JCI Insight. 2023;8(4):e169136. https://doi.org/10.1172/jci.insight.169136.
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Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma

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Authors

Stephen M.F. Jamieson, Peter Tsai, Maria K. Kondratyev, Pratha Budhani, Arthur Liu, Neil N. Senzer, E. Gabriela Chiorean, Shadia I. Jalal, John J. Nemunaitis, Dennis Kee, Avik Shome, Way W. Wong, Dan Li, Nooriyah Poonawala-Lohani, Purvi M. Kakadia, Nicholas S. Knowlton, Courtney R.H. Lynch, Cho R. Hong, Tet Woo Lee, Reidar A. Grénman, Laura Caporiccio, Trevor D. McKee, Mark Zaidi, Sehrish Butt, Andrew M.J. Macann, Nicholas P. McIvor, John M. Chaplin, Kevin O. Hicks, Stefan K. Bohlander, Bradly G. Wouters, Charles P. Hart, Cristin G. Print, William R. Wilson, Michael A. Curran, Francis W. Hunter

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The determinants of complication trajectories in American Indians with type 2 diabetes
Evan L. Reynolds, … , Eva L. Feldman, Brian C. Callaghan
Evan L. Reynolds, … , Eva L. Feldman, Brian C. Callaghan
Published February 8, 2023
Citation Information: JCI Insight. 2023;8(3):e168732. https://doi.org/10.1172/jci.insight.168732.
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The determinants of complication trajectories in American Indians with type 2 diabetes

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Authors

Evan L. Reynolds, Gulcin Akinci, Mousumi Banerjee, Helen C. Looker, Adam Patterson, Robert G. Nelson, Eva L. Feldman, Brian C. Callaghan

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Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis
Lucy V. Norling, … , Charles N. Serhan, Mauro Perretti
Lucy V. Norling, … , Charles N. Serhan, Mauro Perretti
Published February 8, 2023
Citation Information: JCI Insight. 2023;8(3):e168728. https://doi.org/10.1172/jci.insight.168728.
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Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis

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Authors

Lucy V. Norling, Sarah E. Headland, Jesmond Dalli, Hildur H. Arnardottir, Oliver Haworth, Hefin R. Jones, Daniel Irimia, Charles N. Serhan, Mauro Perretti

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Hyperglycemia exacerbates dengue virus infection by facilitating poly(A)-binding protein–mediated viral translation
Ting-Jing Shen, … , Chia-Yi Yu, Chiou-Feng Lin
Ting-Jing Shen, … , Chia-Yi Yu, Chiou-Feng Lin
Published January 24, 2023
Citation Information: JCI Insight. 2023;8(2):e168446. https://doi.org/10.1172/jci.insight.168446.
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Hyperglycemia exacerbates dengue virus infection by facilitating poly(A)-binding protein–mediated viral translation

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Abstract

Authors

Ting-Jing Shen, Chia-Ling Chen, Tsung-Ting Tsai, Ming-Kai Jhan, Chyi-Huey Bai, Yu-Chun Yen, Ching-Wen Tsai, Po-Chun Tseng, Chia-Yi Yu, Chiou-Feng Lin

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Early-life low-calorie sweetener consumption disrupts glucose regulation, sugar-motivated behavior, and memory function in rats
Linda Tsan, … , Scott E. Kanoski, Lindsey A. Schier
Linda Tsan, … , Scott E. Kanoski, Lindsey A. Schier
Published December 22, 2022
Citation Information: JCI Insight. 2022;7(24):e167266. https://doi.org/10.1172/jci.insight.167266.
View: Text | PDF | Amended Article

Early-life low-calorie sweetener consumption disrupts glucose regulation, sugar-motivated behavior, and memory function in rats

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Authors

Linda Tsan, Sandrine Chometton, Anna M.R. Hayes, Molly E. Klug, Yanning Zuo, Shan Sun, Lana Bridi, Rae Lan, Anthony A. Fodor, Emily E. Noble, Xia Yang, Scott E. Kanoski, Lindsey A. Schier

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Differential role of MLKL in alcohol-associated and non–alcohol-associated fatty liver diseases in mice and humans
Tatsunori Miyata, … , Srinivasan Dasarathy, Laura E. Nagy
Tatsunori Miyata, … , Srinivasan Dasarathy, Laura E. Nagy
Published December 8, 2022
Citation Information: JCI Insight. 2022;7(23):e167011. https://doi.org/10.1172/jci.insight.167011.
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Differential role of MLKL in alcohol-associated and non–alcohol-associated fatty liver diseases in mice and humans

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Authors

Tatsunori Miyata, Xiaoqin Wu, Xiude Fan, Emily Huang, Carlos Sanz-Garcia, Christina K. Cajigas-Du Ross, Sanjoy Roychowdhury, Annette Bellar, Megan R. McMullen, Jaividhya Dasarathy, Daniela S. Allende, Joan Caballeria, Pau Sancho-Bru, Craig J. McClain, Mack Mitchell, Arthur J. McCullough, Svetlana Radaeva, Bruce Barton, Gyongyi Szabo, Srinivasan Dasarathy, Laura E. Nagy

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Immunopathogenesis of hidradenitis suppurativa and response to anti–TNF-α therapy
Margaret M. Lowe, … , Scott L. Hansen, Michael D. Rosenblum
Margaret M. Lowe, … , Scott L. Hansen, Michael D. Rosenblum
Published October 24, 2022
Citation Information: JCI Insight. 2022;7(20):e165502. https://doi.org/10.1172/jci.insight.165502.
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Immunopathogenesis of hidradenitis suppurativa and response to anti–TNF-α therapy

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Authors

Margaret M. Lowe, Haley B. Naik, Sean Clancy, Mariela Pauli, Kathleen M. Smith, Yingtao Bi, Robert Dunstan, Johann E. Gudjonsson, Maia Paul, Hobart Harris, Esther Kim, Uk Sok Shin, Richard Ahn, Wilson Liao, Scott L. Hansen, Michael D. Rosenblum

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Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis
Magdalena B. Flak, … , Jesmond Dalli, Costantino Pitzalis
Magdalena B. Flak, … , Jesmond Dalli, Costantino Pitzalis
Published October 24, 2022
Citation Information: JCI Insight. 2022;7(20):e165600. https://doi.org/10.1172/jci.insight.165600.
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Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis

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Abstract

Authors

Magdalena B. Flak, Romain A. Colas, Estefanía Muñoz-Atienza, Michael A. Curtis, Jesmond Dalli, Costantino Pitzalis

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PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma
Gaurav Sharma, … , Dmitry I. Gabrilovich, Ravi K. Amaravadi
Gaurav Sharma, … , Dmitry I. Gabrilovich, Ravi K. Amaravadi
Published October 24, 2022
Citation Information: JCI Insight. 2022;7(20):e165688. https://doi.org/10.1172/jci.insight.165688.
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PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma

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Authors

Gaurav Sharma, Rani Ojha, Estela Noguera-Ortega, Vito W. Rebecca, John Attanasio, Shujing Liu, Shengfu Piao, Jennifer J. Lee, Michael C. Nicastri, Sandra L. Harper, Amruta Ronghe, Vaibhav Jain, Jeffrey D. Winkler, David W. Speicher, Jerome Mastio, Phyllis A. Gimotty, Xiaowei Xu, E. John Wherry, Dmitry I. Gabrilovich, Ravi K. Amaravadi

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Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling
Leila B. Giron, … , Timothy J. Henrich, Mohamed Abdel-Mohsen
Leila B. Giron, … , Timothy J. Henrich, Mohamed Abdel-Mohsen
Published September 22, 2022
Citation Information: JCI Insight. 2022;7(18):e164813. https://doi.org/10.1172/jci.insight.164813.
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Markers of fungal translocation are elevated during post-acute sequelae of SARS-CoV-2 and induce NF-κB signaling

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Abstract

Authors

Leila B. Giron, Michael J. Peluso, Jianyi Ding, Grace Kenny, Netanel F. Zilberstein, Jane Koshy, Kai Ying Hong, Heather Rasmussen, Gregory E. Miller, Faraz Bishehsari, Robert A. Balk, James N. Moy, Rebecca Hoh, Scott Lu, Aaron R. Goldman, Hsin-Yao Tang, Brandon C. Yee, Ahmed Chenna, John W. Winslow, Christos J. Petropoulos, J. Daniel Kelly, Haimanot Wasse, Jeffrey N. Martin, Qin Liu, Ali Keshavarzian, Alan Landay, Steven G. Deeks, Timothy J. Henrich, Mohamed Abdel-Mohsen

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