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Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort
William Z. Zhang, … , Mary E. Choi, the SPIROMICS Investigators
William Z. Zhang, … , Mary E. Choi, the SPIROMICS Investigators
Published June 24, 2024
Citation Information: JCI Insight. 2024;9(12):e181925. https://doi.org/10.1172/jci.insight.181925.
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Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort

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Abstract

Authors

William Z. Zhang, Michelle C. Rice, Katherine L. Hoffman, Clara Oromendia, Igor Z. Barjaktarevic, J. Michael Wells, Annette T. Hastie, Wassim W. Labaki, Christopher B. Cooper, Alejandro P. Comellas, Gerard J. Criner, Jerry A. Krishnan, Robert Paine III, Nadia N. Hansel, Russell P. Bowler, R. Graham Barr, Stephen P. Peters, Prescott G. Woodruff, Jeffrey L. Curtis, Meilan K. Han, Karla V. Ballman, Fernando J. Martinez, Augustine M.K. Choi, Kiichi Nakahira, Suzanne M. Cloonan, Mary E. Choi, the SPIROMICS Investigators

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Longitudinal trajectories of branched chain amino acids through young adulthood and diabetes in later life
Konrad T. Sawicki, … , Janet K. Snell-Bergeon, John T. Wilkins
Konrad T. Sawicki, … , Janet K. Snell-Bergeon, John T. Wilkins
Published June 10, 2024
Citation Information: JCI Insight. 2024;9(11):e181901. https://doi.org/10.1172/jci.insight.181901.
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Longitudinal trajectories of branched chain amino acids through young adulthood and diabetes in later life

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Abstract

Authors

Konrad T. Sawicki, Hongyan Ning, Norrina B. Allen, Mercedes R. Carnethon, Amisha Wallia, James D. Otvos, Issam Ben-Sahra, Elizabeth M. McNally, Janet K. Snell-Bergeon, John T. Wilkins

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Tubular CPT1A deletion minimally affects aging and chronic kidney injury
Safaa Hammoud, … , Irfan J. Lodhi, Leslie S. Gewin
Safaa Hammoud, … , Irfan J. Lodhi, Leslie S. Gewin
Published May 8, 2024
Citation Information: JCI Insight. 2024;9(9):e181816. https://doi.org/10.1172/jci.insight.181816.
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Tubular CPT1A deletion minimally affects aging and chronic kidney injury

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Abstract

Authors

Safaa Hammoud, Alla Ivanova, Yosuke Osaki, Steven Funk, Haichun Yang, Olga Viquez, Rachel Delgado, Dongliang Lu, Melanie Phillips Mignemi, Jane Tonello, Selene Colon, Louise Lantier, David H. Wasserman, Benjamin D. Humphreys, Jeffrey Koenitzer, Justin Kern, Mark de Caestecker, Toren Finkel, Agnes Fogo, Nidia Messias, Irfan J. Lodhi, Leslie S. Gewin

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Circadian regulation of lung repair and regeneration
Amruta Naik, … , Edward E. Morrisey, Shaon Sengupta
Amruta Naik, … , Edward E. Morrisey, Shaon Sengupta
Published March 8, 2024
Citation Information: JCI Insight. 2024;9(5):e179745. https://doi.org/10.1172/jci.insight.179745.
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Circadian regulation of lung repair and regeneration

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Abstract

Authors

Amruta Naik, Kaitlyn M. Forrest, Oindrila Paul, Yasmine Issah, Utham K. Valekunja, Soon Y. Tang, Akhilesh B. Reddy, Elizabeth J. Hennessy, Thomas G. Brooks, Fatima Chaudhry, Apoorva Babu, Michael Morley, Jarod A. Zepp, Gregory R. Grant, Garret A. FitzGerald, Amita Sehgal, G. Scott Worthen, David B. Frank, Edward E. Morrisey, Shaon Sengupta

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miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2
Enrique Fuentes-Mattei, … , George A. Calin, Roxana S. Redis
Enrique Fuentes-Mattei, … , George A. Calin, Roxana S. Redis
Published February 8, 2024
Citation Information: JCI Insight. 2024;9(3):e178762. https://doi.org/10.1172/jci.insight.178762.
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miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2

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Abstract

Authors

Enrique Fuentes-Mattei, Recep Bayraktar, Taghi Manshouri, Andreia M. Silva, Cristina Ivan, Diana Gulei, Linda Fabris, Nayra Soares do Amaral, Pilar Mur, Cristina Perez, Elizabeth Torres-Claudio, Mihnea P. Dragomir, Adriana Badillo-Perez, Erik Knutsen, Pranav Narayanan, Leonard Golfman, Masayoshi Shimizu, Xinna Zhang, Wanke Zhao, Wanting Tina Ho, Marcos Roberto Estecio, Geoffrey Bartholomeusz, Ciprian Tomuleasa, Ioana Berindan-Neagoe, Patrick A. Zweidler-McKay, Zeev Estrov, Zhizhuang J. Zhao, Srdan Verstovsek, George A. Calin, Roxana S. Redis

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Single-cell transcriptomics reveals variations in monocytes and Tregs between gout flare and remission
Hanjie Yu, … , Ling Wang, Ai Peng
Hanjie Yu, … , Ling Wang, Ai Peng
Published February 8, 2024
Citation Information: JCI Insight. 2024;9(3):e179067. https://doi.org/10.1172/jci.insight.179067.
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Single-cell transcriptomics reveals variations in monocytes and Tregs between gout flare and remission

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Authors

Hanjie Yu, Wen Xue, Hanqing Yu, Yaxiang Song, Xinying Liu, Ling Qin, Shu Wang, Hui Bao, Hongchen Gu, Guangqi Chen, Dake Zhao, Yang Tu, Jiafen Cheng, Liya Wang, Zisheng Ai, Dayong Hu, Ling Wang, Ai Peng

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Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo
Sadia Samer, … , Francois J. Villinger, Elena Martinelli
Sadia Samer, … , Francois J. Villinger, Elena Martinelli
Published November 22, 2023
Citation Information: JCI Insight. 2023;8(22):e176882. https://doi.org/10.1172/jci.insight.176882.
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Blockade of TGF-β signaling reactivates HIV-1/SIV reservoirs and immune responses in vivo

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Abstract

Authors

Sadia Samer, Yanique Thomas, Mariluz Araínga, Crystal Carter, Lisa M. Shirreff, Muhammad S. Arif, Juan M. Avita, Ines Frank, Michael D. McRaven, Christopher T. Thuruthiyil, Veli B. Heybeli, Meegan R. Anderson, Benjamin Owen, Arsen Gaisin, Deepanwita Bose, Lacy M. Simons, Judd F. Hultquist, James Arthos, Claudia Cicala, Irini Sereti, Philip J. Santangelo, Ramon Lorenzo-Redondo, Thomas J. Hope, Francois J. Villinger, Elena Martinelli

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Human hepatic organoids for the analysis of human genetic diseases
Yuan Guan, … , Julien Sage, Gary Peltz
Yuan Guan, … , Julien Sage, Gary Peltz
Published October 23, 2023
Citation Information: JCI Insight. 2023;8(20):e176034. https://doi.org/10.1172/jci.insight.176034.
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Human hepatic organoids for the analysis of human genetic diseases

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Abstract

Authors

Yuan Guan, Dan Xu, Phillip M. Garfin, Ursula Ehmer, Melissa Hurwitz, Greg Enns, Sara Michie, Manhong Wu, Ming Zheng, Toshihiko Nishimura, Julien Sage, Gary Peltz

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Platelets exacerbate cardiovascular inflammation in a murine model of Kawasaki disease vasculitis
Begüm Kocatürk, … , Magali Noval Rivas, Moshe Arditi
Begüm Kocatürk, … , Magali Noval Rivas, Moshe Arditi
Published September 25, 2023
Citation Information: JCI Insight. 2023;8(17):e174463. https://doi.org/10.1172/jci.insight.174463.
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Platelets exacerbate cardiovascular inflammation in a murine model of Kawasaki disease vasculitis

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Abstract

Authors

Begüm Kocatürk, Youngho Lee, Nobuyuki Nosaka, Masanori Abe, Daisy Martinon, Malcolm E. Lane, Debbie Moreira, Shuang Chen, Michael C. Fishbein, Rebecca A. Porritt, Bernardo S. Franklin, Magali Noval Rivas, Moshe Arditi

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CD84 is a regulator of the immunosuppressive microenvironment in multiple myeloma
Hadas Lewinsky, … , Steven Rosen, Idit Shachar
Hadas Lewinsky, … , Steven Rosen, Idit Shachar
Published July 24, 2023
Citation Information: JCI Insight. 2023;8(14):e173312. https://doi.org/10.1172/jci.insight.173312.
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CD84 is a regulator of the immunosuppressive microenvironment in multiple myeloma

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Abstract

Authors

Hadas Lewinsky, Emine G. Gunes, Keren David, Lihi Radomir, Matthias P. Kramer, Bianca Pellegrino, Michal Perpinial, Jing Chen, Ting-fang He, Anthony G. Mansour, Kun-Yu Teng, Supriyo Bhattacharya, Enrico Caserta, Estelle Troadec, Peter Lee, Mingye Feng, Jonathan Keats, Amrita Krishnan, Michael Rosenzweig, Jianhua Yu, Michael A. Caligiuri, Yosef Cohen, Olga Shevetz, Shirly Becker-Herman, Flavia Pichiorri, Steven Rosen, Idit Shachar

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