Author's Take

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Omega-3 fatty acids ameliorate placental inflammation induced by oral bacterium
In this episode, Han Yiping and colleagues reveal how an oral bacterium induces placental inflammation and that omega-3 fatty acid supplementation ameliorates this inflammation…
Published February 7, 2019
Author's Take
A biomarker signature of treatment-resistant HPV-related cancer
In this episode, Curtis Pickering and colleagues identify a biomarker signature associated with poor treatment response in HPV-positive oropharyngeal squamous cell carcinoma…
Published January 10, 2019
Author's Take
Drug toxicity testing utilizing human kidney on a chip
In this episode, Edward Kelly and colleagues use human kidney on a chip to evaluate the toxicity of two polymyxin analogs and identify mechanisms of polymyxin-induced toxicity…
Published December 20, 2018
Author's Take
MicroRNA-21 inhibition reduces profibrotic factor release from platelets
In this episode, Manuel Mayr and colleagues identify an ECM-independent mechanism that underlies the antifibrotic effect of miR-21 inhibition…
Published November 26, 2018
Author's Take
Adoptive transfer of EBV-specific T cells in patients with multiple sclerosis
In this episode, Michael Pender and Rajiv Khanna present the results of a phase I trial of EBV-specific T cells for treating progressive multiple sclerosis…
Published November 15, 2018
Author's Take
A model of J wave syndrome
In this episode, Mu Chen, Peng-Shen Chen, and colleagues present a model of J wave syndrome and a potential therapeutic strategy…
Published November 15, 2018
Author's Take
Prostate cancer transcriptional heterogeneity between foci
In this episode, Simpa Salami, Ganesh Palapattu, and colleagues reveal highly heterogenous gene expression within high- and low-grade foci…
Published November 2, 2018
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Maternal malnutrition-induced epigenetic alteration linked to offspring hypertension
In this episode, Toshiro Fujita identify an epigenetic mechanism by which prenatal glucocorticoid exposure promotes adult on-set hypertension…
Published November 2, 2018
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Abnormal neutrophil signature associates with type 1 diabetes
In this episode, Manuela Battaglia and colleagues identify a type 1 diabetes-associated neutrophil signature…
Published October 8, 2018
Author's Take
Maternal high-fat diet linked to inflammatory outcomes in offspring
In this episode, Julie Mirpuri and colleague link maternal high-fat diet to alterations in offspring microbiome with inflammatory consequences…
Published October 4, 2018
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