Author's Take

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Adipose tissue-derived lipocalin-2 promotes kidney injury
In this episode, Wai Yan Sun, Bo Bai, and colleagues reveal that lipocalin-2 production in adipose tissue drives kidney injury…
Published September 6, 2018
Author's Take
Guaiacol improves outcomes in adult polyglucosan body disease model
In this episode, Or Kakhlon and colleagues identify guaiacol as a potential candidate for treating adult polyglucosan body disease (APBD)….
Published September 6, 2018
Author's Take
Tracing Wilm’s tumor 1 to fibrotic lung disease
In this episode, Satish Madala and colleagues reveal Wilms’ tumor 1 as driver of fibrotic lung disease…
Published August 23, 2018
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Cold and a β3 agonist promote adipose beiging in human subjects
In this episode, Philip Kern and colleagues demonstrate adipose beiging in human subjects exposed to cold or the β3 agonist mirabegron…
Published August 9, 2018
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Residual mutant p53 activity linked to cancer survival in males
In this episode, Jean Gariépy and Nicholas Fischer identify residual transcriptional activity of mutant p53 as a prognostic factor for men with glioma and gastric adenocarcinoma…
Published August 9, 2018
Author's Take
Etiology-independent gene signatures of advanced liver fibrosis
In this episode, Matthew Sweet and colleagues identify gene signatures that associated with advanved hepatic fibrosis that are independent of the underlying cause of liver disease...
Published July 25, 2018
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Automated ultrasound segmentation technique for placental volume determination
In this episode, Sally Collins, Pádraig Looney, and colleagues use deep learning to develop an automated technique for determining placental volume…
Published June 7, 2018
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Clinical trial evaluates R. mucosa for atopic dermatitis
In this episode, Ian Myles and colleagues demonstrate that topical administration of Roseomonas mucosa is safe and reduces atopic dermatitis manifestations in patients…
Published May 3, 2018
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Infancy gene signature helps predict type 1 diabetes progression
In this episode, Mark Harris, Ahmed Mehdi, Ranjeny Thomas, and colleagues identify a gene signature in at-risk infants that predicts type 1 diabetes progression…
Published April 23, 2018
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Identification of eosinophilic esophagitis-associated genes
In this episode, Marc Rothenberg and colleagues identify causal variants of DHTKD1 and OGDHL in patients with eosinophilic esophagitis…
Published April 19, 2018
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