DCs are necessary and sufficient for induction of allergic airway inflammation. CD11b+ DCs direct the underlying Th2 immunity, but debate surrounds the function of CD103+ DCs in lung immunity and asthma after an allergic challenge. We challenged
Laura Conejero, Sofía C. Khouili, Sarai Martínez-Cano, Helena M. Izquierdo, Paola Brandi, David Sancho
Batf3-dependent DCs are neither required for lung Treg expansion nor necessary for IL-10 production by lung CD4+ T cells, following HDM airway exposure.