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Lynette M. Sholl, Khanh Do, Priyanka Shivdasani, Ethan Cerami, Adrian M. Dubuc, Frank C. Kuo, Elizabeth P. Garcia, Yonghui Jia, Phani Davineni, Ryan P. Abo, Trevor J. Pugh, Paul van Hummelen, Aaron R. Thorner, Matthew Ducar, Alice H. Berger, Mizuki Nishino, Katherine A. Janeway, Alanna Church, Marian Harris, Lauren L. Ritterhouse, Joshua D. Campbell, Vanesa Rojas-Rudilla, Azra H. Ligon, Shakti Ramkissoon, James M. Cleary, Ursula Matulonis, Geoffrey R. Oxnard, Richard Chao, Vanessa Tassell, James Christensen, William C. Hahn, Philip W. Kantoff, David J. Kwiatkowski, Bruce E. Johnson, Matthew Meyerson, Levi A. Garraway, Geoffrey I. Shapiro, Barrett J. Rollins, Neal I. Lindeman, Laura E. MacConaill
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Concurrent PTEN and PDGFRB Alterations Characterize Storiform Collagenoma
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Genomic and biological study of fusion genes as resistance mechanisms to EGFR inhibitors
Kobayashi Y, Oxnard GR, Cohen EF, Mahadevan NR, Alessi JV, Hung YP, Bertram AA, Heppner DE, Ribeiro MF, Sacardo KP, Saddi R, Macedo MP, Blasco RB, Li J, Kurppa KJ, Nguyen T, Voligny E, Ananda G, Chiarle R, Katz A, Tolstorukov MY, Sholl LM, Jänne PA |
Nature Communications | 2022 |
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Clinical and Molecular Validation of BAP1, MTAP, P53, and Merlin Immunohistochemistry in Diagnosis of Pleural Mesothelioma
Chapel DB, Hornick JL, Barlow J, Bueno R, Sholl LM |
Modern Pathology | 2022 |
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MatchMiner: an open-source platform for cancer precision medicine
Klein H, Mazor T, Siegel E, Trukhanov P, Ovalle A, Vecchio Fitz CD, Zwiesler Z, Kumari P, Van Der Veen B, Marriott E, Hansel J, Yu J, Albayrak A, Barry S, Keller RB, MacConaill LE, Lindeman N, Johnson BE, Rollins BJ, Do KT, Beardslee B, Shapiro G, Hector-Barry S, Methot J, Sholl L, Lindsay J, Hassett MJ, Cerami E |
npj Precision Oncology | 2022 |
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Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes to immune checkpoint inhibitors
Nassar AH, Adib E, Alaiwi SA, Zarif TE, Groha S, Akl EW, Nuzzo PV, Mouhieddine TH, Perea-Chamblee T, Taraszka K, El-Khoury H, Labban M, Fong C, Arora KS, Labaki C, Xu W, Sonpavde G, Haddad RI, Mouw KW, Giannakis M, Hodi FS, Zaitlen N, Schoenfeld AJ, Schultz N, Berger MF, MacConaill LE, Ananda G, Kwiatkowski DJ, Choueiri TK, Schrag D, Carrot-Zhang J, Gusev A |
Cancer Cell | 2022 |
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Evaluation of an inflammation-based score for identification of appropriate patients for comprehensive genomic profiling
Hayashi N, Fukada I, Ohmoto A, Yamazaki M, Wang X, Hosonaga M, Takahashi S |
2022 | |
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NUTM1-Rearranged Carcinoma of the Thyroid: A Distinct Subset of NUT Carcinoma Characterized by Frequent NSD3-NUTM1 fusions
Barletta JA, Gilday SD, Afkhami M, Bell D, Bocklage T, Boisselier P, Chau NG, Cipriani NA, Costes-Martineau V, Ghossein RA, Hertzler HJ, Kramer AM, Limaye S, Lopez CA, Ng TL, Weissferdt A, Xu B, Zhang S, French CA |
The American Journal of Surgical Pathology | 2022 |
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Genome-wide mapping of somatic mutation rates uncovers drivers of cancer.
Sherman MA, Yaari AU, Priebe O, Dietlein F, Loh PR, Berger B |
Nature Biotechnology | 2022 |
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Association of Machine Learning-Based Assessment of Tumor-Infiltrating Lymphocytes on Standard Histologic Images With Outcomes of Immunotherapy in Patients With NSCLC.
Rakaee M, Adib E, Ricciuti B, Sholl LM, Shi W, Alessi JV, Cortellini A, Fulgenzi CAM, Viola P, Pinato DJ, Hashemi S, Bahce I, Houda I, Ulas EB, Radonic T, Väyrynen JP, Richardsen E, Jamaly S, Andersen S, Donnem T, Awad MM, Kwiatkowski DJ |
JAMA Oncology | 2022 |
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Phase I Study Evaluating Glesatinib (MGCD265), An Inhibitor of MET and AXL, in Patients with Non-small Cell Lung Cancer and Other Advanced Solid Tumors.
Kollmannsberger C, Hurwitz H, Bazhenova L, Cho BC, Hong D, Park K, Reckamp KL, Sharma S, Der-Torossian H, Christensen JG, Faltaos D, Potvin D, Tassell V, Chao R, Shapiro GI |
Targeted Oncology | 2022 |
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Organoids
Zhao Z, Chen X, Dowbaj AM, Sljukic A, Bratlie K, Lin L, Fong EL, Balachander GM, Chen Z, Soragni A, Huch M, Zeng YA, Wang Q, Yu H |
2022 | |
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RAF1 amplification drives a subset of bladder tumors and confers sensitivity to MAPK-directed therapeutics
Raie T. Bekele, Amruta S. Samant, Amin H. Nassar, Jonathan So, Elizabeth Garcia, Catherine R. Curran, Justin H. Hwang, David L. Mayhew, Anwesha Nag, Aaron R. Thorner, Judit Börcsök, Zsofia Sztupinszki, Chong-Xian Pan, Joaquim Bellmunt, David J. Kwiatkowski, Guru Sonpavde, Eliezer Van Allen, Kent W Mouw |
Journal of Clinical Investigation | 2021 |
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A Germinal Center-Associated Microenvironmental Signature Reflects Malignant Phenotype and Outcome of DLBCL
K Miyawaki, K Kato, T Sugio, K Sasaki, H Miyoshi, Y Semba, Y Kikushige, Y Mori, Y Kunisaki, H Iwasaki, T Miyamoto, FC Kuo, JC Aster, K Ohshima, T Maeda, K Akashi |
Blood Advances | 2021 |
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Immunogenomics in personalized cancer treatments
K Kiyotani, Y Toyoshima, Y Nakamura |
Journal of Human Genetics | 2021 |
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Personalized immunotherapy in cancer precision medicine
K Kiyotani, Y Toyoshima, Y Nakamura |
Cancer biology & medicine | 2021 |
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FGFR2 Extracellular Domain In-Frame Deletions Are Therapeutically Targetable Genomic Alterations That Function as Oncogenic Drivers in Cholangiocarcinoma
JM Cleary, S Raghavan, Q Wu, YY Li, LF Spurr, HV Gupta, DA Rubinson, IJ Fetter, JL Hornick, JA Nowak, G Siravegna, L Goyal, L Shi, LK Brais, M Loftus, AB Shinagare, TA Abrams, TE Clancy, J Wang, AK Patel, F Brichory, AV Chessex, RJ Sullivan, RB Keller, S Denning, ER Hill, GI Shapiro, A Pokorska-Bocci, C Zanna, K Ng, D Schrag, PA Jänne, WC Hahn, AD Cherniack, RB Corcoran, M Meyerson, A Daina, V Zoete, N Bardeesy, BM Wolpin |
Cancer Discovery | 2021 |
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Interstitial lung abnormalities in patients with stage I non-small cell lung cancer are associated with shorter overall survival: the Boston lung cancer study
T Hida, A Hata, J Lu, VI Valtchinov, T Hino, M Nishino, H Honda, N Tomiyama, DC Christiani, H Hatabu |
Cancer Imaging | 2021 |
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High Sensitivity of Plasma Cell-Free DNA Genotyping in Cases With Evidence of Adequate Tumor Content
CB Meador, MS Milan, EY Hu, MM Awad, MS Rabin, CP Paweletz, R Hartmaier, G Laus, GR Oxnard |
JCO Precision Oncology | 2021 |
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Genomic Evolution in a Patient With Lung Adenocarcinoma With a Germline EGFR T790M Mutation
N Mäkinen, M Zhou, M Bemus, J Nevin, A Nag, R Chen, YL Colson, AR Thorner, GR Oxnard, M Meyerson, LM Sholl |
2021 | |
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Clinical Inflection Point Detection on the Basis of EHR Data to Identify Clinical Trial–Ready Patients With Cancer
KL Kehl, S Groha, EM Lepisto, H Elmarakeby, J Lindsay, A Gusev, EM Allen, MJ Hassett, D Schrag |
JCO Clinical Cancer Informatics | 2021 |
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Real-World Performance of a Comprehensive Genomic Profiling Test Optimized for Small Tumor Samples
SA Tomlins, DH Hovelson, JM Suga, DM Anderson, HA Koh, EC Dees, B McNulty, ME Burkard, M Guarino, J Khatri, MM Safa, MR Matrana, ES Yang, AR Menter, BM Parsons, JN Slim, MA Thompson, L Hwang, WJ Edenfield, S Nair, A Onitilo, R Siegel, A Miller, T Wassenaar, WJ Irvin, W Schulz, A Padmanabhan, V Harish, A Gonzalez, AH Mansoor, A Kellum, P Harms, S Drewery, J Falkner, A Fischer, J Hipp, K Kwiatkowski, LL de la Vega, K Mitchell, T Reeder, J Siddiqui, H Vakil, DB Johnson, DR Rhodes |
JCO Precision Oncology | 2021 |
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Therapeutic Implications of Germline Testing in Patients With Advanced Cancers
ZK Stadler, A Maio, D Chakravarty, Y Kemel, M Sheehan, E Salo-Mullen, K Tkachuk, CJ Fong, B Nguyen, A Erakky, K Cadoo, Y Liu, MI Carlo, A Latham, H Zhang, R Kundra, S Smith, J Galle, C Aghajanian, N Abu-Rustum, A Varghese, EM O'Reilly, M Morris, W Abida, M Walsh, A Drilon, G Jayakumaran, A Zehir, M Ladanyi, O Ceyhan-Birsoy, DB Solit, N Schultz, MF Berger, D Mandelker, LA Diaz, K Offit, ME Robson |
Journal of Clinical Oncology | 2021 |
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Association between Smoking History and Tumor Mutation Burden in Advanced Non–Small Cell Lung Cancer
X Wang, B Ricciuti, T Nguyen, X Li, MS Rabin, MM Awad, X Lin, BE Johnson, DC Christiani |
Cancer research | 2021 |
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Precision Medicine for Colorectal Cancer with Liquid Biopsy and Immunotherapy
S Nagayama, SK Low, K Kiyotani, Y Nakamura |
Cancers | 2021 |
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Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors
EF Cobain, YM Wu, P Vats, R Chugh, F Worden, DC Smith, SM Schuetze, MM Zalupski, V Sahai, A Alva, AF Schott, ME Caram, DF Hayes, EM Stoffel, MF Jacobs, C Kumar-Sinha, X Cao, R Wang, D Lucas, Y Ning, E Rabban, J Bell, S Camelo-Piragua, AM Udager, M Cieslik, RJ Lonigro, LP Kunju, DR Robinson, M Talpaz, AM Chinnaiyan |
JAMA Oncology | 2021 |
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Ceralasertib-Mediated ATR Inhibition Combined With Olaparib in Advanced Cancers Harboring DNA Damage Response and Repair Alterations (Olaparib Combinations)
H Mahdi, N Hafez, D Doroshow, D Sohal, V Keedy, KT Do, P LoRusso, J Jürgensmeier, M Avedissian, J Sklar, C Glover, B Felicetti, E Dean, P Mortimer, GI Shapiro, JP Eder |
JCO Precision Oncology | 2021 |
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Phase II Clinical Trial of Everolimus in a Pan-Cancer Cohort of Patients with mTOR Pathway Alterations
E Adib, K Klonowska, K Giannikou, KT Do, S Pruitt-Thompson, K Bhushan, MI Milstein, J Hedglin, KE Kargus, LM Sholl, J Tsuji, DM Hyman, A Sisk, GI Shapiro, HA Vargas, JJ Harding, MH Voss, G Iyer, DJ Kwiatkowski |
Clinical cancer research | 2021 |
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Clinical cancer genomic profiling
D Chakravarty, DB Solit |
Nature Reviews Genetics | 2021 |
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Twists and turns from “tumor in tumor” profiling: surveillance of chronic lymphocytic leukemia (CLL) leads to detection of a lung adenocarcinoma, whose genomic characterization alters the original hematologic diagnosis
P Terraf, LM Sholl, MS Davids, MM Awad, EP Garcia, LE MacConaill, PD Cin, A Kim, NI Lindeman, M Stachler, DH Hwang, AM Dubuc |
Molecular Case Studies | 2021 |
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Conditionally Reprogrammed Cells and Robotic High-Throughput Screening for Precision Cancer Therapy
F Alkhilaiwi |
Frontiers in Oncology | 2021 |
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Characterization of genetics in patients with mucosal melanoma treated with immune checkpoint blockade
EI Buchbinder, JL Weirather, M Manos, BJ Quattrochi, LM Sholl, RC Brennick, P Bowling, N Bailey, L Magarace, PA Ott, R Haq, B Izar, A GiobbieHurder, FS Hodi |
Cancer Medicine | 2021 |
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Race and Genetic Alterations in Prostate Cancer
FR Schumacher, SP Basourakos, PJ Lewicki, R Vince, DE Spratt, CE Barbieri, JE Shoag |
JCO Precision Oncology | 2021 |
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Re-evaluating tumors of purported specialized prostatic stromal origin reveals molecular heterogeneity, including non-recurring gene fusions characteristic of uterine and soft tissue sarcoma subtypes
AM Acosta, LM Sholl, BC Dickson, JK McKenney, JB Gordetsky, MR Pins, A Marino-Enriquez, F Dong, AM Dubuc, PD Cin, CD Fletcher |
Modern Pathology | 2021 |
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Uterine tumor resembling an ovarian sex cord tumor: A case report and review of literature
FF Zhou, YT He, Y Li, M Zhang, FH Chen |
World journal of clinical cases | 2021 |
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A Replication stress biomarker is associated with response to gemcitabine versus combined gemcitabine and ATR inhibitor therapy in ovarian cancer
PA Konstantinopoulos, AA da Costa, D Gulhan, EK Lee, SC Cheng, AE Hendrickson, B Kochupurakkal, DL Kolin, EC Kohn, JF Liu, EH Stover, J Curtis, N Tayob, M Polak, D Chowdhury, UA Matulonis, A Färkkilä, AD DAndrea, GI Shapiro |
Nature Communications | 2021 |
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Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity
NR Mahadevan, EH Knelson, JO Wolff, A Vajdi, M Saigí, M Campisi, D Hong, TC Thai, B Piel, S Han, BB Reinhold, JS Duke-Cohan, MJ Poitras, LJ Taus, PH Lizotte, A Portell, V Quadros, AD Santucci, T Murayama, I Cañadas, S Kitajima, A Akitsu, M Fridrikh, H Watanabe, B Reardon, PC Gokhale, CP Paweletz, MM Awad, EM Allen, A Lako, , B Chen, F Hong, LM Sholl, MY Tolstorukov, K Pfaff, PA Jänne, E Gjini, R Edwards, S Rodig, EL Reinherz, MG Oser, DA Barbie |
Cancer Discovery | 2021 |
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ERK Inhibitor LY3214996-Based Treatment Strategies for RAS -Driven Lung Cancer
J Köhler, Y Zhao, J Li, PC Gokhale, HL Tiv, AR Knott, MK Wilkens, KM Soroko, M Lin, C Ambrogio, M Musteanu, A Ogino, J Choi, M Bahcall, AA Bertram, ES Chambers, CP Paweletz, SV Bhagwat, JR Manro, RV Tiu, PA Jänne |
Molecular cancer therapeutics | 2021 |
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Constructing germline research cohorts from the discarded reads of clinical tumor sequences
A Gusev, S Groha, K Taraszka, YR Semenov, N Zaitlen |
Genome Medicine | 2021 |
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Oncogenic switch and single-agent MET inhibitor sensitivity in a subset of EGFR -mutant lung cancer
PÖ Eser, RM Paranal, J Son, E Ivanova, Y Kuang, HM Haikala, C To, JJ Okoro, KH Dholakia, J Choi, Y Eum, A Ogino, P Missios, D Ercan, M Xu, MJ Poitras, S Wang, K Ngo, M Dills, M Yanagita, T Lopez, M Lin, J Tsai, N Floch, ES Chambers, J Heng, R Anjum, AD Santucci, K Michael, AG Schuller, D Cross, PD Smith, GR Oxnard, DA Barbie, LM Sholl, M Bahcall, S Palakurthi, PC Gokhale, CP Paweletz, GQ Daley, PA Jänne |
Science Translational Medicine | 2021 |
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nab -Sirolimus for Patients With Malignant Perivascular Epithelioid Cell Tumors
AJ Wagner, V Ravi, RF Riedel, K Ganjoo, BA Tine, R Chugh, L Cranmer, EM Gordon, JL Hornick, H Du, B Grigorian, AN Schmid, S Hou, K Harris, DJ Kwiatkowski, NP Desai, MA Dickson |
Journal of Clinical Oncology | 2021 |
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Assessment of genomic alterations in non-syndromic von Hippel-Lindau: Insight from integrating somatic and germline next generation sequencing genomic data
DK Manning, P Shivdasani, DR Koeller, A Schwartz, HQ Rana, JE Garber, NI Lindeman, AA Ghazani |
Data in Brief | 2021 |
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Germline Sequencing Improves Tumor-Only Sequencing Interpretation in a Precision Genomic Study of Patients With Pediatric Solid Tumor
J Schienda, AJ Church, LB Corson, B Decker, CM Clinton, DK Manning, A Imamovic-Tuco, D Reidy, GR Strand, MA Applebaum, R Bagatell, SG DuBois, JL Glade-Bender, W Kang, AR Kim, TW Laetsch, ME Macy, L Maese, N Pinto, AJ Sabnis, JD Schiffman, SI Colace, SL Volchenboum, DA Weiser, JA Nowak, NI Lindeman, KA Janeway, BD Crompton, J Kamihara |
JCO Precision Oncology | 2021 |
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Artificial intelligence-aided clinical annotation of a large multi-cancer genomic dataset
KL Kehl, W Xu, A Gusev, Z Bakouny, TK Choueiri, IB Riaz, H Elmarakeby, EM Allen, D Schrag |
Nature Communications | 2021 |
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Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer
S Raghavan, P Winter, A Navia, H Williams, A DenAdel, K Lowder, J Galvez-Reyes, R Kalekar, N Mulugeta, K Kapner, M Raghavan, A Borah, N Liu, S Väyrynen, A Costa, R Ng, J Wang, E Hill, D Ragon, L Brais, A Jaeger, L Spurr, Y Li, A Cherniack, M Booker, E Cohen, M Tolstorukov, I Wakiro, A Rotem, B Johnson, J McFarland, E Sicinska, T Jacks, R Sullivan, G Shapiro, T Clancy, K Perez, D Rubinson, K Ng, J Cleary, L Crawford, S Manalis, J Nowak, B Wolpin, W Hahn, A Aguirre, A Shalek |
Cell | 2021 |
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FGFR2/3 g enomic alterations and response to Enfortumab Vedotin in metastatic urothelial carcinoma
E Adib, T ElZarif, R Jain, W Skelton, D Freeman, C Curran, E Akl, A Nassar, P Ravi, C Mantia, D Kwiatkowski, T Choueiri, G Sonpavde |
2021 | |
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CDKN2A Alterations and Response to Immunotherapy in Solid Tumors
E Adib, A Nassar, E Akl, S Alaiwi, P Nuzzo, T Mouhieddine, G Sonpavde, R Haddad, K Mouw, M Giannakis, F Hodi, S Shukla, A Gusev, D Braun, T Choueiri, D Kwiatkowski |
Clinical cancer research | 2021 |
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Combined PARP and HSP90 inhibition: preclinical and Phase 1 evaluation in patients with advanced solid tumours
P Konstantinopoulos, S Cheng, J Supko, M Polak, A Wahner-Hendrickson, S Ivy, B Bowes, H Sawyer, P Basada, M Hayes, J Curtis, N Horowitz, A Wright, S Campos, E Ivanova, C Paweletz, S Palakurthi, J Liu, A DAndrea, P Gokhale, D Chowdhury, U Matulonis, G Shapiro |
British Journal of Cancer | 2021 |
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Molecular Characterization and Therapeutic Targeting of Colorectal Cancers Harboring Receptor Tyrosine Kinase Fusions
H Singh, Y Li, L Spurr, A Shinagare, R Abhyankar, E Reilly, L Brais, A Nag, M Ducar, A Thorner, G Shapiro, R Keller, C Siletti, J Clark, A Farago, J Lin, G Demetri, R Gujrathi, M Kulke, L MacConaill, A Ligon, E Sicinska, M Meyerson, J Meyerhardt, A Cherniack, B Wolpin, K Ng, M Giannakis, J Hornick, J Cleary |
Clinical cancer research | 2021 |
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Clinical utility of targeted next-generation sequencing assay in IDH-wildtype glioblastoma for therapy decision-making
Lim-Fat MJ, Youssef GC, Touat M, Iorgulescu JB, Whorral S, Allen M, Rahman R, Chukwueke U, McFaline-Figueroa JR, Nayak L, Lee EQ, Batchelor TT, Arnaout O, Peruzzi PP, Chiocca EA, Reardon DA, Meredith D, Santagata S, Beroukhim R, Bi WL, Ligon KL, Wen PY |
Neuro-Oncology | 2021 |
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Neoadjuvant and Adjuvant Nivolumab and Lirilumab in Patients with Recurrent, Resectable Squamous Cell Carcinoma of the Head and Neck.
Hanna GJ, O'Neill A, Shin KY, Wong K, Jo VY, Quinn CT, Cutler JM, Flynn M, Lizotte PH, Annino DJ Jr, Goguen LA, Kass JI, Rettig EM, Sethi RKV, Lorch JH, Schoenfeld JD, Margalit DN, Tishler RB, Everett PC, Desai AM, Cavanaugh ME, Paweletz CP, Egloff AM, Uppaluri R, Haddad RI |
Clinical cancer research | 2021 |
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Tumor Growth Rate After Nadir Is Associated With Survival in Patients With EGFR-Mutant Non–Small-Cell Lung Cancer Treated With Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor
Nishino M, Lu J, Hino T, Vokes NI, Jänne PA, Hatabu H, Johnson BE |
JCO Precision Oncology | 2021 |
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Belzutifan, a Potent HIF2α Inhibitor, in the Pacak–Zhuang Syndrome
Kamihara J, Hamilton KV, Pollard JA, Clinton CM, Madden JA, Lin J, Imamovic A, Wall CB, Wassner AJ, Weil BR, Heeney MM, Vargas SO, Kaelin WG Jr, Janeway KA, Perini RF, Zojwalla NJ, Voss SD, DuBois SG |
The New England journal of medicine | 2021 |
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Clinical and molecular characterization of virus-positive and virus-negative Merkel cell carcinoma
GJ Starrett, M Thakuria, T Chen, C Marcelus, J Cheng, J Nomburg, AR Thorner, MK Slevin, W Powers, RT Burns, C Perry, A Piris, FC Kuo, G Rabinowits, A Giobbie-Hurder, LE MacConaill, JA DeCaprio |
Genome Medicine | 2020 |
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Identification of a RAS-activating TMEM87A–RASGRF1 Fusion in an Exceptional Responder to Sunitinib with Non–Small Cell Lung Cancer
AJ Cooper, Y Kobayashi, D Kim, SE Clifford, S Kravets, SE Dahlberg, ES Chambers, J Li, D Rangachari, T Nguyen, DB Costa, MS Rabin, N Wagle, LM Sholl, PA Jänne, GR Oxnard |
Clinical cancer research | 2020 |
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Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer Therapy
L Hinze, R Labrosse, J Degar, T Han, EM Schatoff, S Schreek, S Karim, C McGuckin, JR Sacher, F Wagner, M Stanulla, C Yuan, E Sicinska, M Giannakis, K Ng, LE Dow, A Gutierrez |
Cancer Discovery | 2020 |
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Detection of ERBB2 amplification in uterine serous carcinoma by next-generation sequencing: an approach highly concordant with standard assays
CL Robinson, BT Harrison, AH Ligon, F Dong, V Maffeis, U Matulonis, MR Nucci, DL Kolin |
Modern Pathology | 2020 |
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Genomic and Immunologic Characterization of INI1-Deficient Pediatric Cancers
SJ Forrest, A Al-Ibraheemi, D Doan, A Ward, CM Clinton, J Putra, RS Pinches, C Kadoch, SN Chi, SG DuBois, PJ Leavey, NR LeBoeuf, E Mullen, N Collins, AJ Church, KA Janeway |
Clinical cancer research | 2020 |
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Genomic and pathological heterogeneity in clinically diagnosed small cell lung cancer in never/light smokers identifies therapeutically targetable alterations
A Ogino, J Choi, M Lin, MK Wilkens, A Calles, M Xu, AE Adeni, ES Chambers, M Capelletti, M Butaney, NS Gray, PC Gokhale, S Palakurthi, P Kirschmeier, GR Oxnard, LM Sholl, PA Jänne |
Molecular Oncology | 2020 |
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Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
JE Neggers, BR Paolella, A Asfaw, MV Rothberg, TA Skipper, A Yang, RL Kalekar, JM Krill-Burger, NV Dharia, G Kugener, J Kalfon, C Yuan, N Dumont, A Gonzalez, M Abdusamad, YY Li, LF Spurr, WW Wu, AD Durbin, BM Wolpin, F Piccioni, DE Root, JS Boehm, AD Cherniack, A Tsherniak, AL Hong, WC Hahn, K Stegmaier, TR Golub, F Vazquez, AJ Aguirre |
Cell Reports | 2020 |
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ViroPanel
MK Slevin, BM Wollison, W Powers, RT Burns, N Patel, MD Ducar, GJ Starrett, EP Garcia, DK Manning, J Cheng, GJ Hanna, KM Kaye, PV Hummelen, A Nag, AR Thorner, JA DeCaprio, LE MacConaill |
The Journal of molecular diagnostics : JMD | 2020 |
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Lung-only melanoma: UV mutational signature supports origin from occult cutaneous primaries and argues against the concept of primary pulmonary melanoma
C Yang, F Sanchez-Vega, JC Chang, WK Chatila, AN Shoushtari, M Ladanyi, WD Travis, KJ Busam, N Rekhtman |
Modern Pathology | 2020 |
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Predictors of immunotherapy benefit in Merkel cell carcinoma
AJ Kacew, H Dharaneeswaran, GJ Starrett, M Thakuria, NR LeBoeuf, AW Silk, JA DeCaprio, GJ Hanna |
Oncotarget | 2020 |
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Establishment of a Molecular Tumor Board (MTB) and Uptake of Recommendations in a Community Setting
A VanderWalde, A Grothey, D Vaena, G Vidal, A ElNaggar, G Bufalino, L Schwartzberg |
Journal of Personalized Medicine | 2020 |
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Combined CDK4/6 and PD-1 Inhibition in Refractory SMARCA4-Deficient Small-Cell Carcinoma of the Ovary, Hypercalcemic Type
EK Lee, KM Esselen, DL Kolin, LJ Lee, UA Matulonis, PA Konstantinopoulos |
JCO Precision Oncology | 2020 |
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Impact and Diagnostic Gaps of Comprehensive Genomic Profiling in Real-World Clinical Practice
AP Singh, E Shum, L Rajdev, H Cheng, S Goel, R Perez-Soler, B Halmos |
Cancers | 2020 |
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Development of Genome-Derived Tumor Type Prediction to Inform Clinical Cancer Care
A Penson, N Camacho, Y Zheng, AM Varghese, H Al-Ahmadie, P Razavi, S Chandarlapaty, CE Vallejo, E Vakiani, T Gilewski, JE Rosenberg, M Shady, DW Tsui, DN Reales, A Abeshouse, A Syed, A Zehir, N Schultz, M Ladanyi, DB Solit, DS Klimstra, DM Hyman, BS Taylor, MF Berger |
JAMA Oncology | 2020 |
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Mechanisms and therapeutic implications of hypermutation in gliomas
M Touat, YY Li, AN Boynton, LF Spurr, JB Iorgulescu, CL Bohrson, I Cortes-Ciriano, C Birzu, JE Geduldig, K Pelton, MJ Lim-Fat, S Pal, R Ferrer-Luna, SH Ramkissoon, F Dubois, C Bellamy, N Currimjee, J Bonardi, K Qian, P Ho, S Malinowski, L Taquet, RE Jones, A Shetty, KH Chow, R Sharaf, D Pavlick, LA Albacker, N Younan, C Baldini, M Verreault, M Giry, E Guillerm, S Ammari, F Beuvon, K Mokhtari, A Alentorn, C Dehais, C Houillier, F Laigle-Donadey, D Psimaras, EQ Lee, L Nayak, JR McFaline-Figueroa, A Carpentier, P Cornu, L Capelle, B Mathon, JS Barnholtz-Sloan, A Chakravarti, WL Bi, EA Chiocca, KP Fehnel, S Alexandrescu, SN Chi, D Haas-Kogan, TT Batchelor, GM Frampton, BM Alexander, RY Huang, AH Ligon, F Coulet, JY Delattre, K Hoang-Xuan, DM Meredith, S Santagata, A Duval, M Sanson, AD Cherniack, PY Wen, DA Reardon, A Marabelle, PJ Park, A Idbaih, R Beroukhim, P Bandopadhayay, F Bielle, KL Ligon |
Nature | 2020 |
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Assessment of Temporal Selection Bias in Genomic Testing in a Cohort of Patients With Cancer
KL Kehl, D Schrag, MJ Hassett, H Uno |
2020 | |
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Molecular profiling for precision cancer therapies
ER Malone, M Oliva, PJ Sabatini, TL Stockley, LL Siu |
Genome Medicine | 2020 |
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Strategies for the successful implementation of plasma-based NSCLC genotyping in clinical practice
C Aggarwal, CD Rolfo, GR Oxnard, JE Gray, LM Sholl, DR Gandara |
Nature Reviews Clinical Oncology | 2020 |
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Beyond the Variants: Mutational Patterns in Next-Generation Sequencing Data for Cancer Precision Medicine
M Parilla, LL Ritterhouse |
Frontiers in Cell and Developmental Biology | 2020 |
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Genomic profiling of pleomorphic and florid lobular carcinoma in situ reveals highly recurrent ERBB2 and ERRB3 alterations
BT Harrison, F Nakhlis, DA Dillon, TR Soong, EP Garcia, SJ Schnitt, TA King |
Modern Pathology | 2020 |
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Detection of the KITD816V mutation in myelodysplastic and/or myeloproliferative neoplasms and acute myeloid leukemia with myelodysplasia-related changes predicts concurrent systemic mastocytosis
JW Craig, RP Hasserjian, AS Kim, JC Aster, GS Pinkus, JL Hornick, DP Steensma, RC Lindsley, DJ DeAngelo, EA Morgan |
Modern Pathology | 2020 |
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Identification of prognostic factors in childhood T‐cell acute lymphoblastic leukemia: Results from DFCI ALL Consortium Protocols 05‐001 and 11‐001
MA Burns, AE Place, KE Stevenson, A Gutiérrez, S Forrest, Y Pikman, LM Vrooman, MH Harris, OK Weinberg, SK Hunt, JE O'Brien, BL Asselin, UH Athale, LA Clavell, PD Cole, LM Gennarini, JM Kahn, KM Kelly, C Laverdiere, JM Leclerc, B Michon, MA Schorin, ML Sulis, JJ Welch, DS Neuberg, SE Sallan, LB Silverman |
Pediatric Blood & Cancer | 2020 |
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Cas9 activates the p53 pathway and selects for p53-inactivating mutations
OM Enache, V Rendo, M Abdusamad, D Lam, D Davison, S Pal, N Currimjee, J Hess, S Pantel, A Nag, AR Thorner, JG Doench, F Vazquez, R Beroukhim, TR Golub, U Ben-David |
Nature Genetics | 2020 |
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A Novel SS18-SSX Fusion-specific Antibody for the Diagnosis of Synovial Sarcoma
E Baranov, MJ McBride, AM Bellizzi, AH Ligon, CD Fletcher, C Kadoch, JL Hornick |
The American Journal of Surgical Pathology | 2020 |
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Real-world outcomes treating patients with advanced cutaneous squamous cell carcinoma with immune checkpoint inhibitors (CPI)
GJ Hanna, ES Ruiz, NR LeBoeuf, M Thakuria, CD Schmults, JA Decaprio, AW Silk |
British Journal of Cancer | 2020 |
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Mammalian SWI/SNF Complex Genomic Alterations and Immune Checkpoint Blockade in Solid Tumors
SA Alaiwi, AH Nassar, W Xie, Z Bakouny, JE Berchuck, DA Braun, SC Baca, PV Nuzzo, R Flippot, TH Mouhieddine, LF Spurr, YY Li, T Li, A Flaifel, JA Steinharter, CA Margolis, NI Vokes, H Du, SA Shukla, AD Cherniack, G Sonpavde, RI Haddad, MM Awad, M Giannakis, FS Hodi, XS Liu, S Signoretti, C Kadoch, ML Freedman, DJ Kwiatkowski, EM Allen, TK Choueiri |
Cancer immunology research | 2020 |
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ARID1A mutations and expression loss in non-small cell lung carcinomas: clinicopathologic and molecular analysis
YP Hung, A Redig, JL Hornick, LM Sholl |
Modern Pathology | 2020 |
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Tumor Mutational Burden and PTEN Alterations as Molecular Correlates of Response to PD-1/L1 Blockade in Metastatic Triple-Negative Breast Cancer
R Barroso-Sousa, TE Keenan, S Pernas, P Exman, E Jain, AC Garrido-Castro, M Hughes, B Bychkovsky, R Umeton, JL Files, NI Lindeman, LE MacConaill, FS Hodi, IE Krop, D Dillon, EP Winer, N Wagle, NU Lin, EA Mittendorf, EM Allen, SM Tolaney |
Clinical cancer research | 2020 |
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Phase IB Study of Osimertinib in Combination with Navitoclax in EGFR -mutant NSCLC Following Resistance to Initial EGFR Therapy (ETCTN 9903)
EM Bertino, RD Gentzler, S Clifford, J Kolesar, A Muzikansky, EB Haura, Z Piotrowska, DR Camidge, TE Stinchcombe, C Hann, J Malhotra, LC Villaruz, CP Paweletz, CL Lau, L Sholl, N Takebe, JA Moscow, GI Shapiro, PA Jänne, GR Oxnard |
Clinical cancer research | 2020 |
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Novel Pathogenic Germline Variant of the Adenomatous Polyposis Coli (APC) Gene, p.S2627Gfs*12 Identified in a Mild Phenotype of APC-Associated Polyposis: A Case Report
DR Koeller, A Schwartz, DK Manning, F Dong, NI Lindeman, JE Garber, AA Ghazani |
American Journal of Case Reports | 2020 |
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Genomic Characterization of de novo Metastatic Breast Cancer
AC Garrido-Castro, LF Spurr, ME Hughes, YY Li, AD Cherniack, P Kumari, MR Lloyd, B Bychkovsky, R Barroso-Sousa, SD Lascio, E Jain, J Files, A Mohammed-Abreu, M Krevalin, C MacKichan, WT Barry, H Guo, D Xia, E Cerami, BJ Rollins, LE MacConaill, NI Lindeman, IE Krop, BE Johnson, N Wagle, EP Winer, DA Dillon, NU Lin |
Clinical cancer research | 2020 |
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Natural Language Processing to Ascertain Cancer Outcomes From Medical Oncologist Notes
KL Kehl, W Xu, E Lepisto, H Elmarakeby, MJ Hassett, EM Allen, BE Johnson, D Schrag |
JCO Clinical Cancer Informatics | 2020 |
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Lung cancer biomarker tests: the history and perspective in Japan
N Motoi, Y Yatabe |
Translational Lung Cancer Research | 2020 |
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The Benefits of Adjuvant Trastuzumab for HER‐2‐Positive Salivary Gland Cancers
GJ Hanna, JE Bae, JH Lorch, RI Haddad, VY Jo, JD Schoenfeld, DN Margalit, RB Tishler, LA Goguen, DJ Annino, NG Chau |
The oncologist | 2020 |
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Discovery through clinical sequencing in oncology
M Donoghue, A Schram, D Hyman, B Taylor |
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Telomere length alterations and ATRX/DAXX loss in pituitary adenomas.
Heaphy CM, Bi WL, Coy S, Davis C, Gallia GL, Santagata S, Rodriguez FJ |
Modern Pathology | 2020 |
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Clinical Pan-Cancer Assessment of Mismatch Repair Deficiency Using Tumor-Only, Targeted Next-Generation Sequencing
Albayrak A, Garrido-Castro AC, Giannakis M, Umeton R, Manam MD, Stover EH, Porter RL, Johnson BE, Liaw KL, Amonkar M, Church AJ, Janeway KA, Nowak JA, Sholl L, Lin NU, Johnson JM |
JCO Precision Oncology | 2020 |
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Systematic analysis of the intersection of disease mutations with protein modifications
CM Simpson, B Zhang, PV Hornbeck, F Gnad |
BMC Medical Genomics | 2019 |
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Genomic heterogeneity and efficacy of PI3K pathway inhibitors in patients with gynaecological cancer
V Rodriguez-Freixinos, F Ruiz-Pace, L Fariñas-Madrid, AC Garrido-Castro, G Villacampa, P Nuciforo, A Vivancos, R Dienstmann, A Oaknin |
ESMO Open | 2019 |
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Adamantinoma-like Ewing Sarcoma of the Salivary Glands: A Newly Recognized Mimicker of Basaloid Salivary Carcinomas
LM Rooper, VY Jo, CR Antonescu, V Nose, WH Westra, RR Seethala, JA Bishop |
The American Journal of Surgical Pathology | 2019 |
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Molecular Analysis of Plasma From Patients With ROS1-Positive NSCLC
I Dagogo-Jack, M Rooney, RJ Nagy, JJ Lin, E Chin, LA Ferris, J Ackil, JK Lennerz, RB Lanman, JF Gainor, AT Shaw |
Journal of Thoracic Oncology | 2019 |
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Impact of molecular testing in clinical practice in gynecologic cancers
M Huang, T Hunter, B Slomovitz, M Schlumbrecht |
Cancer Medicine | 2019 |
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Clinical utility of custom-designed NGS panel testing in pediatric tumors
LF Surrey, SP MacFarland, F Chang, K Cao, KS Rathi, GT Akgumus, D Gallo, F Lin, A Gleason, P Raman, R Aplenc, R Bagatell, J Minturn, Y Mosse, M Santi, SK Tasian, AJ Waanders, M Sarmady, JM Maris, SP Hunger, MM Li |
Genome Medicine | 2019 |
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Assessment of Deep Natural Language Processing in Ascertaining Oncologic Outcomes From Radiology Reports
KL Kehl, H Elmarakeby, M Nishino, EM Allen, EM Lepisto, MJ Hassett, BE Johnson, D Schrag |
JAMA Oncology | 2019 |
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EGFR mutant locally advanced non-small cell lung cancer is at increased risk of brain metastasis
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Clinical and Translational Radiation Oncology | 2019 |
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MET IHC Is a Poor Screen for MET Amplification or MET Exon 14 Mutations in Lung Adenocarcinomas: Data from a Tri-Institutional Cohort of the Lung Cancer Mutation Consortium
R Guo, LD Berry, DL Aisner, J Sheren, T Boyle, PA Bunn, BE Johnson, DJ Kwiatkowski, A Drilon, LM Sholl, MG Kris |
Journal of Thoracic Oncology | 2019 |
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Integrative Molecular Analysis of Patients With Advanced and Metastatic Cancer
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Imaging of Precision Therapy for Lung Cancer: Current State of the Art
H Park, LM Sholl, H Hatabu, MM Awad, M Nishino |
Radiology | 2019 |
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OCTANE (Ontario-wide Cancer Targeted Nucleic Acid Evaluation): a platform for intraprovincial, national, and international clinical data-sharing
ER Malone, RR Saleh, C Yu, L Ahmed, T Pugh, J Torchia, J Bartlett, C Virtanen, SJ Hotte, J Hilton, S Welch, A Robinson, E McCready, B Lo, B Sadikovic, H Feilotter, TP Hanna, S Kamel-Reid, TL Stockley, LL Siu, PL Bedard |
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Treatment with Next-Generation ALK Inhibitors Fuels Plasma ALK Mutation Diversity
I Dagogo-Jack, M Rooney, JJ Lin, RJ Nagy, BY Yeap, H Hubbeling, E Chin, J Ackil, AF Farago, AN Hata, JK Lennerz, JF Gainor, RB Lanman, AT Shaw |
Clinical cancer research | 2019 |
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Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia
GP Pouliot, J Degar, L Hinze, B Kochupurakkal, CD Vo, MA Burns, L Moreau, C Ganesa, J Roderick, S Peirs, B Menten, ML Loh, SP Hunger, LB Silverman, MH Harris, KE Stevenson, DM Weinstock, AP Weng, PV Vlierberghe, AD DAndrea, A Gutierrez, V Coppola |
PloS one | 2019 |
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Molecular characterization of localized pleural mesothelioma
YP Hung, F Dong, AM Dubuc, PD Cin, R Bueno, LR Chirieac |
Modern Pathology | 2019 |
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Mutation Yield of a Custom 212-Gene Next-Generation Sequencing Panel for Solid Tumors: Clinical Experience of the First 260 Cases Tested Using the JAX ActionSeq™ Assay
P Selvam, MC Hsiao, G Omerza, D Bergeron, S Rowe, J Uvalic, M Soucy, M Peracchio, S Burns, B Meyers, M Prego, Q Nie, G Ananda, H Chandok, K Kelly, A Hesse, HV Reddi |
Molecular diagnosis & therapy | 2019 |
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Harmonization of Tumor Mutational Burden Quantification and Association With Response to Immune Checkpoint Blockade in Non–Small-Cell Lung Cancer
NI Vokes, D Liu, B Ricciuti, E Jimenez-Aguilar, H Rizvi, F Dietlein, MX He, CA Margolis, HA Elmarakeby, J Girshman, A Adeni, F Sanchez-Vega, N Schultz, S Dahlberg, A Zehir, PA Jänne, M Nishino, R Umeton, LM Sholl, EM Allen, MD Hellmann, MM Awad |
JCO Precision Oncology | 2019 |
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A model combining clinical and genomic factors to predict response to PD-1/PD-L1 blockade in advanced urothelial carcinoma
AH Nassar, KW Mouw, O Jegede, AB Shinagare, J Kim, CJ Liu, M Pomerantz, LC Harshman, EM Allen, XX Wei, B McGregor, AD Choudhury, MA Preston, F Dong, S Signoretti, NI Lindeman, J Bellmunt, TK Choueiri, G Sonpavde, DJ Kwiatkowski |
British Journal of Cancer | 2019 |
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Uterine Tumor Resembling Ovarian Sex Cord Tumor (UTROSCT): A Morphologic and Molecular Study of 26 Cases Confirms Recurrent NCOA1-3 Rearrangement
EA Goebel, SH Bonilla, F Dong, BC Dickson, LN Hoang, D Hardisson, MD Lacambra, FI Lu, CD Fletcher, CP Crum, CR Antonescu, MR Nucci, DL Kolin |
The American Journal of Surgical Pathology | 2019 |
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Identifying ERBB2 Activating Mutations in HER2-Negative Breast Cancer: Clinical Impact of Institute-Wide Genomic Testing and Enrollment in Matched Therapy Trials
P Exman, AC Garrido-Castro, ME Hughes, RA Freedman, T Li, L Trippa, BL Bychkovsky, R Barroso-Sousa, SD Lascio, C Mackichan, MR Lloyd, M Krevalin, E Cerami, MS Merrill, R Santiago, L Crowley, N Kuhnly, J Files, NI Lindeman, LE MacConaill, P Kumari, SM Tolaney, IE Krop, R Bose, BE Johnson, CX Ma, DA Dillon, EP Winer, N Wagle, NU Lin |
JCO Precision Oncology | 2019 |
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Characterization of Activating Mutations of the MEK1 Gene in Papillary Thyroid Carcinomas
N Borrelli, F Panebianco, V Condello, JA Barletta, C Kaya, L Yip, MN Nikiforova, YE Nikiforov |
Thyroid | 2019 |
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Olaparib and α-specific PI3K inhibitor alpelisib for patients with epithelial ovarian cancer: a dose-escalation and dose-expansion phase 1b trial
PA Konstantinopoulos, WT Barry, M Birrer, SN Westin, KA Cadoo, GI Shapiro, EL Mayer, RE O'Cearbhaill, RL Coleman, B Kochupurakkal, C Whalen, J Curtis, S Farooq, W Luo, J Eismann, MK Buss, C Aghajanian, GB Mills, S Palakurthi, P Kirschmeier, J Liu, LC Cantley, SH Kaufmann, EM Swisher, AD D'Andrea, E Winer, GM Wulf, UA Matulonis |
The Lancet Oncology | 2019 |
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Phase II Study of Avelumab in Patients With Mismatch Repair Deficient and Mismatch Repair Proficient Recurrent/Persistent Endometrial Cancer
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Journal of Clinical Oncology | 2019 |
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Frameshift events predict anti-PD-1/L1 response in head and neck cancer
Glenn Hanna, Patrick Lizotte, Megan Cavanaugh, Frank C. Kuo, Priyanka Shivdasani, Alexander Frieden, Nicole Chau, Jonathan Schoenfeld, Jochen Lorch, Ravindra Uppaluri, Laura MacConaill, Robert Haddad |
JCI Insight | 2018 |
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Improved outcomes in PI3K pathway altered metastatic HPV oropharyngeal cancer
Glenn J Hanna, Alec Kacew, Nicole Grace Chau, Priyanka Shivdasani, Jochen Lorch, Ravindra Uppaluri, Robert Haddad, Laura MacConaill |
JCI Insight | 2018 |
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Association of Cell-Free DNA Tumor Fraction and Somatic Copy Number Alterations With Survival in Metastatic Triple-Negative Breast Cancer
DG Stover, HA Parsons, G Ha, SS Freeman, WT Barry, H Guo, AD Choudhury, G Gydush, SC Reed, J Rhoades, D Rotem, ME Hughes, DA Dillon, AH Partridge, N Wagle, IE Krop, G Getz, TR Golub, JC Love, EP Winer, SM Tolaney, NU Lin, VA Adalsteinsson |
Journal of Clinical Oncology | 2018 |
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Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response
DE Park, J Cheng, C Berrios, J Montero, M Cortés-Cros, S Ferretti, R Arora, ML Tillgren, PC Gokhale, JA DeCaprio |
Proceedings of the National Academy of Sciences | 2018 |
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Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine
AJ Aguirre, JA Nowak, ND Camarda, RA Moffitt, AA Ghazani, M Hazar-Rethinam, S Raghavan, J Kim, LK Brais, D Ragon, MW Welch, E Reilly, D McCabe, L Marini, K Anderka, K Helvie, N Oliver, A Babic, AD Silva, B Nadres, EE Seventer, HA Shahzade, JP Pierre, KP Burke, T Clancy, JM Cleary, LA Doyle, K Jajoo, NJ McCleary, JA Meyerhardt, JE Murphy, K Ng, AK Patel, K Perez, MH Rosenthal, DA Rubinson, M Ryou, GI Shapiro, E Sicinska, SG Silverman, RJ Nagy, RB Lanman, D Knoerzer, DJ Welsch, MB Yurgelun, CS Fuchs, LA Garraway, G Getz, JL Hornick, BE Johnson, MH Kulke, RJ Mayer, JW Miller, PB Shyn, DA Tuveson, N Wagle, JJ Yeh, WC Hahn, RB Corcoran, SL Carter, BM Wolpin |
Cancer Discovery | 2018 |
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An Acquired NRAS Q61K Mutation in BRAF V600E-Mutant Lung Adenocarcinoma Resistant to Dabrafenib Plus Trametinib
DL Abravanel, M Nishino, LM Sholl, C Ambrogio, MM Awad |
Journal of Thoracic Oncology | 2018 |
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Unique, dual-indexed sequencing adapters with UMIs effectively eliminate index cross-talk and significantly improve sensitivity of massively parallel sequencing
LE MacConaill, RT Burns, A Nag, HA Coleman, MK Slevin, K Giorda, M Light, K Lai, M Jarosz, MS McNeill, MD Ducar, M Meyerson, AR Thorner |
BMC Genomics | 2018 |
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Amplicon-based next-generation sequencing of plasma cell-free DNA for detection of driver and resistance mutations in advanced non-small cell lung cancer
N Guibert, Y Hu, N Feeney, Y Kuang, V Plagnol, G Jones, K Howarth, JF Beeler, CP Paweletz, GR Oxnard |
Annals of Oncology | 2018 |
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Comprehensive Genomic Profiling of Metastatic Tumors in a Phase 2 Biomarker Study of Everolimus in Advanced Renal Cell Carcinoma
X Gao, O Jegede, C Gray, PJ Catalano, J Novak, DJ Kwiatkowski, RR McKay, DJ George, TK Choueiri, DF McDermott, S Signoretti, RS Bhatt |
Clinical Genitourinary Cancer | 2018 |
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The emerging clinical relevance of genomics in cancer medicine
MF Berger, ER Mardis |
Nature Reviews Clinical Oncology | 2018 |
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Genetic and transcriptional evolution alters cancer cell line drug response
U Ben-David, B Siranosian, G Ha, H Tang, Y Oren, K Hinohara, CA Strathdee, J Dempster, NJ Lyons, R Burns, A Nag, G Kugener, B Cimini, P Tsvetkov, YE Maruvka, R ORourke, A Garrity, AA Tubelli, P Bandopadhayay, A Tsherniak, F Vazquez, B Wong, C Birger, M Ghandi, AR Thorner, JA Bittker, M Meyerson, G Getz, R Beroukhim, TR Golub |
Nature | 2018 |
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Prevalence of Clonal Hematopoiesis Mutations in Tumor-Only Clinical Genomic Profiling of Solid Tumors
RN Ptashkin, DL Mandelker, CC Coombs, K Bolton, Z Yelskaya, DM Hyman, DB Solit, J Baselga, ME Arcila, M Ladanyi, L Zhang, RL Levine, MF Berger, A Zehir |
JAMA Oncology | 2018 |
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Clinical and mutational spectrum of highly differentiated, paired box 3:forkhead box protein o1 fusion-negative rhabdomyosarcoma: A report from the Children's Oncology Group: Highly Differentiated Rhabdomyosarcomas
LA Teot, M Schneider, AR Thorner, J Tian, YY Chi, M Ducar, L Lin, M Wlodarski, HE Grier, CD Fletcher, P van Hummelen, SX Skapek, DS Hawkins, AJ Wagers, C Rodriguez-Galindo, S Hettmer |
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Genomic Profiling on an Unselected Solid Tumor Population Reveals a Highly Mutated Wnt/β-Catenin Pathway Associated with Oncogenic EGFR Mutations
J Jiang, A Protopopov, R Sun, S Lyle, M Russell |
Journal of Personalized Medicine | 2018 |
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Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma
G de Velasco, SA Wankowicz, R Madison, SM Ali, C Norton, A Duquette, JS Ross, D Bossé, AK Lalani, VA Miller, PJ Stephens, L Young, AA Hakimi, S Signoretti, SK Pal, TK Choueiri |
British Journal of Cancer | 2018 |
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Everolimus and pazopanib (E/P) benefit genomically selected patients with metastatic urothelial carcinoma
J Bellmunt, AK Lalani, S Jacobus, SA Wankowicz, L Polacek, DY Takeda, LC Harshman, N Wagle, I Moreno, K Lundgren, D Bossé, EM Allen, TK Choueiri, JE Rosenberg |
British Journal of Cancer | 2018 |
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Oncogenic Signaling Pathways in The Cancer Genome Atlas
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Detection of Mutations in Barrett’s Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma
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Assessment of Resistance Mechanisms and Clinical Implications in Patients With EGFR T790M–Positive Lung Cancer and Acquired Resistance to Osimertinib
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