Research LetterIn-Press PreviewCardiologyInflammation
Open Access | 
10.1172/jci.insight.200770
Severity-dependent atrial remodeling and atrial fibrillation vulnerability in a clinically relevant aortic regurgitation mouse model
Robert Lakin,1 Xueyan Liu,1 Dana Sherrard,1 Mihir Parikh,1 Ryan Debi,1 Nazari Polidovitch,1 Markus J. Duncan,2 Jian Wu,3 and Peter H. Backx1
1Department of Biology, York University, Toronto, Canada
2ParticipACTION, Toronto, Canada
3Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
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1Department of Biology, York University, Toronto, Canada
2ParticipACTION, Toronto, Canada
3Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
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1Department of Biology, York University, Toronto, Canada
2ParticipACTION, Toronto, Canada
3Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
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1Department of Biology, York University, Toronto, Canada
2ParticipACTION, Toronto, Canada
3Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
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1Department of Biology, York University, Toronto, Canada
2ParticipACTION, Toronto, Canada
3Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
Find articles by Debi, R. in: PubMed | Google Scholar
1Department of Biology, York University, Toronto, Canada
2ParticipACTION, Toronto, Canada
3Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
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1Department of Biology, York University, Toronto, Canada
2ParticipACTION, Toronto, Canada
3Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
Find articles by Duncan, M. in: PubMed | Google Scholar
1Department of Biology, York University, Toronto, Canada
2ParticipACTION, Toronto, Canada
3Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
Find articles by Wu, J. in: PubMed | Google Scholar
1Department of Biology, York University, Toronto, Canada
2ParticipACTION, Toronto, Canada
3Shanghai Institute of Cardiovascular Diseases, Fudan University, Shanghai, China
Find articles by Backx, P. in: PubMed | Google Scholar
Published March 20, 2026 - More info
Copyright © 2026, Lakin et al. This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
