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Predoctoral MD-PhD grants as indicators of future NIH funding success
Shohini Ghosh-Choudhary, … , Corrine R. Kliment, Richard A. Steinman
Shohini Ghosh-Choudhary, … , Corrine R. Kliment, Richard A. Steinman
Published March 22, 2022
Citation Information: JCI Insight. 2022;7(6):e155688. https://doi.org/10.1172/jci.insight.155688.
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Perspective Physician-Scientist Development Aging

Predoctoral MD-PhD grants as indicators of future NIH funding success

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Abstract

MD-PhD trainees constitute an important source of physician-scientists. Persistence on this challenging path is facilitated by success in garnering independent (R grant) support from the NIH. Published research tracks academic appointments and global R01 success for MD-PhD trainees but has not included information on future funding success of individual MD-PhD predoctoral grant holders. Here, we used data from the NIH RePORTER database to identify and track the funding trajectory of physician-scientists who received predoctoral grant support through the F30 mechanism, which is specific for dual-degree candidates. Male and female F30 awardees did not differ in their success in garnering K (postdoctoral training) grants, but, among F30 grant awardees, men were 2.6 times more likely than women to receive R funding. These results underscore the need for analysis of factors that contribute to the disproportionate loss of NIH-supported female physician-scientists between the predoctoral F30 and the independent R grant–supported stages.

Authors

Shohini Ghosh-Choudhary, Neil Carleton, S. Mehdi Nouraie, Corrine R. Kliment, Richard A. Steinman

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Figure 2

Distribution of F30 awards.

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Distribution of F30 awards.
(A) Overall histogram showing distribution o...
(A) Overall histogram showing distribution of F30 awards to dual-degree MD-PhD trainees over time. (B) The blue line indicates the proportion of F30 recipients who were women by year. The overall proportion of women who received F30 awards was 38.9%; this percentage has increased from below 30% when the F30 awards were first awarded in the 1990s. We note that the proportion of female F30 awardees has remained level beyond the capture period for this study. These rates largely mirror the percentage of women who make up total enrollees in nationwide MSTP programs (indicated by light gray line) (note that the rates indicated for 1990–2000 and 2001–2005 are derived from Akabas and Brass, which show percentage of women graduates, which may differ slightly from the percentage of women enrollees, ref. 7; those for 2011–2019 are from AAMC, ref. 39).

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