Citations to this article
Feng Wang, … , Huilan Zhang, Ziyong Sun
Published April 23, 2020
Citation Information: JCI Insight. 2020;5(10):e137799. https://doi.org/10.1172/jci.insight.137799.
Citation Information: JCI Insight. 2020;5(10):e137799. https://doi.org/10.1172/jci.insight.137799.
Abstract
BACKGROUND The coronavirus disease 2019 (COVID-19), infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a severe outbreak throughout the world. The host immunity of COVID-19 patients is unknown.METHODS The routine laboratory tests and host immunity in COVID-19 patients with different severity of illness were compared after patient admission.RESULTS A total of 65 SARS-CoV-2–positive patients were classified as having mild (n = 30), severe (n = 20), and extremely severe (n = 15) illness. Many routine laboratory tests, such as ferritin, lactate dehydrogenase, and D-dimer, were increased in severe and extremely severe patients. The absolute numbers of CD4+ T cells, CD8+ T cells, and B cells were gradually decreased with increased severity of illness. The activation markers such as HLA-DR and CD45RO expressed on CD4+ and CD8+ T cells were increased in severe and extremely severe patients compared with mild patients. The costimulatory molecule CD28 had opposite results. The percentage of natural Tregs was decreased in extremely severe patients. The percentage of IFN-γ–producing CD8+ T cells was increased in both severe and extremely severe patients compared with mild patients. The percentage of IFN-γ–producing CD4+ T cells was increased in extremely severe patients. IL-2R, IL-6, and IL-10 were all increased in extremely severe patients. The activation of DC and B cells was decreased in extremely severe patients.CONCLUSION The number and function of T cells are inconsistent in COVID-19 patients. The hyperfunction of CD4+ and CD8+ T cells is associated with the pathogenesis of extremely severe SARS-CoV-2 infection.FUNDING This work was funded by the National Mega Project on Major Infectious Disease Prevention (2017ZX10103005-007) and the Fundamental Research Funds for the Central Universities (2019kfyRCPY098).
Authors
Feng Wang, Hongyan Hou, Ying Luo, Guoxing Tang, Shiji Wu, Min Huang, Weiyong Liu, Yaowu Zhu, Qun Lin, Liyan Mao, Minghao Fang, Huilan Zhang, Ziyong Sun
Total citations by year
Citation information
Citations to this article (315)
| Title and authors | Publication | Year |
|---|---|---|
|
Heterogeneity and longitudinal transcriptomic characteristics of Tregs in COVID-19 patients
Wen Y, Zhao J, Zhang Z |
Frontiers in Immunology | 2025 |
|
Deep insight into cytokine storm: from pathogenesis to treatment
Nie J, Zhou L, Tian W, Liu X, Yang L, Yang X, Zhang Y, Wei S, Wang DW, Wei J |
Signal Transduction and Targeted Therapy | 2025 |
|
Susceptibility from the immunological perspective of COVID-19-associated pulmonary aspergillosis: A literature review
Wang J, Ji X, Yang C, Xu J |
Medicine | 2025 |
|
Aging-associated changes in immunological parameters: Implications for COVID-19 immune response in the elderly.
Gasmi M, Hejazi M, Muscella A, Marsigliante S, Sharma A |
Physiological reports | 2025 |
|
Critical biomarkers in the battle against COVID-19: unveiling thrombotic risks and predictive indicators in Syrian hospitals
Al-Kayali R, Youzghati MY, Ibrahim A |
Annals of Medicine and Surgery | 2025 |
|
Insights into estrogen impact in oral health & microbiome in COVID-19
Bayardo-González RA, Peña-Rodríguez M, Pereira-Suárez AL, Rubio-Sánchez AX, García-Chagollán M, Valenzuela-Orozco DN, Lizarazo-Taborda MD, Mora-Mora J, Vega-Magaña N |
BMC Microbiology | 2024 |
|
Clinical Signs and Treatment of New-Onset Bone Marrow Failure Associated SARS-CoV-2 Infection in Children: A Single Institution Prospective Cohort Study.
Youssef MAM, Ahmed ES, Kamal DT, Elsayh KI, Abdelfattah MA, Mahran HH, Embaby MM |
Mediterranean journal of hematology and infectious diseases | 2024 |
|
Dietary patterns and micronutrients in respiratory infections including COVID-19: a narrative review
Salehi Z, Askari M, Jafari A, Ghosn B, Surkan PJ, Hosseinzadeh-Attar MJ, Pouraram H, Azadbakht L |
BMC Public Health | 2024 |
|
Identification of consensus homozygous regions and their associations with growth and feed efficiency traits in American mink
Davoudi P, Do DN, Rathgeber B, Colombo S, Sargolzaei M, Plastow G, Wang Z, Miar Y |
2024 | |
|
Role of histone deacetylase inhibitors in non-neoplastic diseases
Zhou C, Zhao D, Wu C, Wu Z, Zhang W, Chen S, Zhao X, Wu S |
Heliyon | 2024 |
|
Innovation through Artificial Intelligence in Triage Systems for Resource Optimization in Future Pandemics
Garrido NJ, González-Martínez F, Losada S, Plaza A, del Olmo E, Mateo J |
2024 | |
|
Severity of COVID-19 in Pregnant Women: A Review on the Potential Role of Regulatory T Cells.
Saghafi N, Mahmoudi M, Momtazi-Borojeni AA, Mirzaeian S, Tavasolian F, Sathyapalan T, Abdollahi E, Sahebkar A |
Current medicinal chemistry | 2024 |
|
Non-human primate model of long-COVID identifies immune associates of hyperglycemia.
Palmer CS, Perdios C, Abdel-Mohsen M, Mudd J, Datta PK, Maness NJ, Lehmicke G, Golden N, Hellmers L, Coyne C, Moore Green K, Midkiff C, Williams K, Tiburcio R, Fahlberg M, Boykin K, Kenway C, Russell-Lodrigue K, Birnbaum A, Bohm R, Blair R, Dufour JP, Fischer T, Saied AA, Rappaport J |
Nature communications | 2024 |
|
Omicron XBB.1.5 subvariant causes severe pulmonary disease in K18-hACE-2 mice
Elsharkawy A, Stone S, Guglani A, Patterson LD, Ge C, Dim C, Miano JM, Kumar M |
Frontiers in Microbiology | 2024 |
|
Immunopathological markers and cell types linked to COVID-19 symptom manifestation.
Song HW, Jo HY, Kim SC, Choi SS |
BMC infectious diseases | 2024 |
|
In silico assessment of CAR macrophages activity against SARS-CoV-2 infection
Amoddeo A |
Heliyon | 2024 |
|
The Value of Common Laboratory Markers in Predicting the Severity of COVID-19 Patients
Chen L, Jiang YH, Li MY, Huang B, Yuan L, Wan JH, Qin TY, Zeng TT, Chen QG |
Infection and Drug Resistance | 2024 |
|
TIM3 in COVID-19; A potential hallmark?
Zamani MR, Šácha P |
Heliyon | 2024 |
|
T Cells Immunophenotyping and CD38 Overexpression as Hallmarks of the Severity of COVID-19 and Predictors of Patients’ Outcomes
Tarbiah NI, Alkhattabi NA, Alsahafi AJ, Aljahdali HS, Joharjy HM, Al-Zahrani MH, Sabban AM, Alghamdi RA, Balgoon MJ, Khalifa RA |
Journal of Clinical Medicine | 2023 |
|
Persistent humoral and CD4+ TH cell immunity after mild SARS-COV-2 infection—The CoNAN long-term study
Schnizer C, Andreas N, Vivas W, Kamradt T, Baier M, Kiehntopf M, Glöckner S, Scherag A, Löffler B, Kolanos S, Guerra J, Pletz MW, Weis S |
Frontiers in immunology | 2023 |
|
Convalescent plasma (hyperimmune immunoglobulin) for COVID-19 management: An update
Chavda VP, Bezbaruah R, Dolia S, Shah N, Verma S, Savale S, Ray S |
2023 | |
|
Multiplex sensing of IL-10 and CRP towards predicting critical illness in COVID-19 infections
Madhurantakam S, Lee ZJ, Naqvi A, Karnam JB, Muthukumar S, Prasad S |
Biosensors & bioelectronics | 2023 |
|
Investigation of inflammation, oxidative stress, and DNA damage in COVID-19 patients
Tepebaşı MY, İlhan İ, Temel EN, Sancer O, Öztürk Ö |
Cell Stress & Chaperones | 2023 |
|
Immune cell landscape in symptomatic and asymptomatic SARS-CoV-2 infected adults and children in urban Dhaka, Bangladesh
Akhtar E, Mily A, Sarker P, Chanda BC, Haque F, Kuddusi RU, Haq MA, Lourda M, Brighenti S, Raqib R |
Immunobiology | 2023 |
|
The Peripheral Immune Traits Changed in Patients with Multiple System Atrophy
Gong Z, Gao R, Ba L, Liu Y, Hou H, Zhang M |
Brain Sciences | 2023 |
|
T Cell Response to SARS-CoV-2 Coinfection and Comorbidities
Wang L, Peng HY, Pham A, Villazana E, Ballard DJ, Das JK, Kumar A, Xiong X, Song J |
Pathogens | 2023 |
|
Immune cell population and cytokine profiling suggest age dependent differences in the response to SARS-CoV-2 infection
Aragon L, Iribarren-López A, Alberro A, Iparraguirre L, Von Wichmann M, Marimon JM, Saiz-Calderon N, Agudo J, Gálvez MI, Cipitria MC, Prada A, Otaegui D |
2023 | |
|
The Impact of Past COVID-19 Infection on Selected Lymphocyte Subsets in Pediatric Patients
Budziło O, Irga-Jaworska N, Myszyńska M, Malanowska M, Niedźwiecki M |
Human vaccines | 2023 |
|
Dynamic changes in radiological parameters, immune cells, selected miRNAs, and cytokine levels in peripheral blood of patients with severe COVID‑19
Bukreieva T, Kyryk V, Nikulina V, Svitina H, Vega A, Chybisov O, Shablii I, Mankovska O, Lobyntseva G, Nemtinov P, Skrypkina I, Shablii V |
Biomedical Reports | 2023 |
|
Discovery and systematic assessment of early biomarkers that predict progression to severe COVID-19 disease
Hufnagel K, Fathi A, Stroh N, Klein M, Skwirblies F, Girgis R, Dahlke C, Hoheisel JD, Lowy C, Schmidt R, Griesbeck A, Merle U, Addo MM, Schröder C |
2023 | |
|
In the SARS-CoV-2 Pandora Pandemic: Can the Stance of Premorbid Intestinal Innate Immune System as Measured by Fecal Adnab-9 Binding of p87:Blood Ferritin, Yielding the FERAD Ratio, Predict COVID-19 Susceptibility and Survival in a Prospective Population Database?
Tobi M, Bluth MH, Rossi NF, Demian E, Talwar H, Tobi YY, Sochacki P, Levi E, Lawson M, McVicker B |
International journal of molecular sciences | 2023 |
|
Inflammatory Response in COVID-19 Depending on the Severity of the Disease and the Vaccination Status.
Trofin F, Nastase EV, Roșu MF, Bădescu AC, Buzilă ER, Miftode EG, Manciuc DC, Dorneanu OS |
International journal of molecular sciences | 2023 |
|
Documenting the immune response in patients with COVID-19-induced acute respiratory distress syndrome
Lu J, Zeng X, Lu W, Feng J, Yang Y, Wei Y, Chen Y, Zhang J, Pinhu L |
Frontiers in Cell and Developmental Biology | 2023 |
|
Molecular mechanisms of COVID-19-induced pulmonary fibrosis and epithelial-mesenchymal transition.
Pi P, Zeng Z, Zeng L, Han B, Bai X, Xu S |
Frontiers in pharmacology | 2023 |
|
Accelerated T-Cell Immunosenescence in Cytomegalovirus-Seropositive Individuals After Severe Acute Respiratory Syndrome Coronavirus 2 Infection.
Álvarez-Heredia P, Reina-Alfonso I, Domínguez-Del-Castillo JJ, Gutiérrez-González C, Hassouneh F, Batista-Duharte A, Pérez AB, Tarazona R, Solana R, Pera A |
The Journal of Infectious Diseases | 2023 |
|
The Influence of KE and EW Dipeptides in the Composition of the Thymalin Drug on Gene Expression and Protein Synthesis Involved in the Pathogenesis of COVID-19
Linkova N, Khavinson V, Diatlova A, Petukhov M, Vladimirova E, Sukhareva M, Ilina A |
International journal of molecular sciences | 2023 |
|
A new, simple marker for predicting complicated appendicitis in patients with normal white blood cell count indicator; LUC %
Çetinkaya E, Bayazıtlı ŞM, Göktaş A, Akın T, Akgül Ö, Er S, Hamamcı EO, Berkem H, Yüksel BC, Tez M |
2023 | |
|
Immunological responses in SARS-CoV-2 and HIV co-infection versus SARS-CoV-2 mono-infection: case report of the interplay between SARS-CoV-2 and HIV
Shahbaz S, Sligl W, Osman M, Elahi S |
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology | 2023 |
|
Secondary pulmonary infection and co-infection in elderly COVID-19 patients during the pandemics in a tertiary general hospital in Beijing, China
Zhou C, Jiang Y, Sun L, Li H, Liu X, Huang L |
Frontiers in microbiology | 2023 |
|
Assessing the gene expression of the adenosine 5'-monophosphate-activated protein kinase (AMPK) and its relation with the IL-6 and IL-10 plasma levels in COVID-19 patients.
Assar S, Dastbaz M, Amini K, Roghani SA, Lotfi R, Taghadosi M, Kafi H, Abdan Z, Allahyari H, Rostampour R, Shahrokhvand SZ |
Molecular Biology Reports | 2023 |
|
Functional principal component analysis and sparse-group LASSO to identify associations between biomarker trajectories and mortality among hospitalized SARS-CoV-2 infected individuals.
Cao T, Reeder HT, Foulkes AS |
BMC medical research methodology | 2023 |
|
Comprehensive antibody and cytokine profiling in hospitalized COVID-19 patients in relation to clinical outcomes in a large Belgian cohort
Ruytinx P, Vandormael P, Fraussen J, Pieters Z, Thonissen S, Hellings N, Stinissen P, Callebaut I, Penders J, Vanhove K, Kieffer D, Rummens JL, Valkenborgh T, Messiaen P, Stessel B, Mesotten D, Somers V |
Scientific Reports | 2023 |
|
Immune response to SARS-CoV-2 vaccination in relation to peripheral immune cell profiles among patients with multiple sclerosis receiving ocrelizumab
S Räuber, M Korsen, N Huntemann, L Rolfes, T Müntefering, V Dobelmann, A Hermann, T Kölsche, K von Wnuck Lipinski, C Schroeter, C Nelke, L Regner-Nelke, J Ingwersen, M Pawlitzki, B Teegen, M Barnett, H Hartung, O Aktas, P Albrecht, B Levkau, N Melzer, T Ruck, S Meuth, D Kremer |
Journal of neurology, neurosurgery, and psychiatry | 2022 |
|
Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
J Lee, D Kim, B Min |
Frontiers in immunology | 2022 |
|
COVID-19 and the role of cytokines in this disease
A Hasanvand |
Inflammopharmacology | 2022 |
|
SARS-Cov2 acute and post-active infection in the context of autoimmune and chronic inflammatory diseases
R Larionova, K Byvaltsev, О Kravtsova, E Takha, S Petrov, G Kazarian, A Valeeva, E Shuralev, M Mukminov, Y Renaudineau, M Arleevskaya |
2022 | |
|
Regulatory T Cells: Angels or Demons in the Pathophysiology of Sepsis?
Y Gao, Y Yao, X Zhang, F Chen, X Meng, X Chen, C Wang, Y Liu, X Tian, S Shou, Y Chai |
Frontiers in immunology | 2022 |
|
Elevated Cytokine Levels in Plasma of Patients with SARS-CoV-2 Do Not Contribute to Pulmonary Microvascular Endothelial Permeability
A Kovacs-Kasa, A Zaied, S Leanhart, M Koseoglu, S Sridhar, R Lucas, D Fulton, J Vazquez, B Annex, Y Sui |
Microbiology spectrum | 2022 |
|
Mechanistic Insights Into the Immune Pathophysiology of COVID-19; An In-Depth Review
A Shafqat, S Shafqat, S Salameh, J Kashir, K Alkattan, A Yaqinuddin |
Frontiers in immunology | 2022 |
|
An integrated framework for identifying clinical-laboratory indicators for novel pandemics: COVID-19 and MIS-C
A Nahari, M Son, J Newburger, B Reis |
2022 | |
|
Activated CD8+CD38+ Cells Are Associated With Worse Clinical Outcome in Hospitalized COVID-19 Patients
A Bobcakova, M Barnova, R Vysehradsky, J Petriskova, I Kocan, Z Diamant, M Jesenak |
Frontiers in immunology | 2022 |
|
An Early Th1 Response Is a Key Factor for a Favorable COVID-19 Evolution
F Gil-Etayo, S Garcinuño, A Utrero-Rico, O Cabrera-Marante, D Arroyo-Sanchez, E Mancebo, D Pleguezuelo, E Rodríguez-Frías, L Allende, P Morales-Pérez, M Castro-Panete, A Lalueza, C Lumbreras, E Paz-Artal, A Serrano |
Biomedicines | 2022 |
|
The Association between TNF-α, IL-6, and Vitamin D Levels and COVID-19 Severity and Mortality: A Systematic Review and Meta-Analysis
C Halim, A Mirza, M Sari |
Pathogens | 2022 |
|
Role of T Regulatory Cells and Myeloid-Derived Suppressor Cells in COVID-19
A Alsalman, M Al-Mterin, E Elkord, M Dwivedi |
Journal of Immunology Research | 2022 |
|
Vitamin D can reduce severity in COVID-19 through regulation of PD-L1.
Aygun H |
Naunyn-Schmiedeberg's Archives of Pharmacology | 2022 |
|
Sustained Impairment in Cardiopulmonary Exercise Capacity Testing in Patients after COVID-19: A Single Center Experience.
Evers G, Schulze AB, Osiaevi I, Harmening K, Vollenberg R, Wiewrodt R, Pistulli R, Boentert M, Tepasse PR, Sindermann JR, Yilmaz A, Mohr M |
2022 | |
|
A Detailed Overview of Immune Escape, Antibody Escape, Partial Vaccine Escape of SARS-CoV-2 and Their Emerging Variants With Escape Mutations.
Chakraborty C, Sharma AR, Bhattacharya M, Lee SS |
Frontiers in immunology | 2022 |
|
From COVID-19 to Sarcoidosis: How Similar Are These Two Diseases?
Zhao M, Tian C, Cong S, Di X, Wang K |
Frontiers in immunology | 2022 |
|
Immune system changes in those with hypertension when infected with SARS-CoV-2
Su S, Chen R, Zhang S, Shu H, Luo J |
Cellular Immunology | 2022 |
|
Potential Immune Indicators for Predicting the Prognosis of COVID-19 and Trauma: Similarities and Disparities.
Fouladseresht H, Ghamar Talepoor A, Eskandari N, Norouzian M, Ghezelbash B, Beyranvand MR, Nejadghaderi SA, Carson-Chahhoud K, Kolahi AA, Safiri S |
Frontiers in immunology | 2022 |
|
Evaluation of ferritin level in COVID-19 patients and its inflammatory response.
Chen J, He ZX, Wang FK |
Applied Nanoscience | 2022 |
|
HLA-C*04:01 Affects HLA Class I Heterozygosity and Predicted Affinity to SARS-CoV-2 Peptides, and in Combination With Age and Sex of Armenian Patients Contributes to COVID-19 Severity.
Hovhannisyan A, Madelian V, Avagyan S, Nazaretyan M, Hyussyan A, Sirunyan A, Arakelyan R, Manukyan Z, Yepiskoposyan L, Mayilyan KR, Jordan F |
Frontiers in immunology | 2022 |
|
Increased Expression of Tim-3 Is Associated With Depletion of NKT Cells In SARS-CoV-2 Infection.
Yang J, Chang T, Tang L, Deng H, Chen D, Luo J, Wu H, Tang T, Zhang C, Li Z, Dong L, Yang XP, Tang ZH |
Frontiers in immunology | 2022 |
|
Tacrolimus-resistant SARS-CoV-2-specific T cell products to prevent and treat severe COVID-19 in immunosuppressed patients.
Peter L, Wendering DJ, Schlickeiser S, Hoffmann H, Noster R, Wagner DL, Zarrinrad G, Münch S, Picht S, Schulenberg S, Moradian H, Mashreghi MF, Klein O, Gossen M, Roch T, Babel N, Reinke P, Volk HD, Amini L, Schmueck-Henneresse M |
2022 | |
|
Antigens and Antibodies of the Antiphospholipid Syndrome as New Allies in the Pathogenesis of COVID-19 Coagulopathy.
Serrano M, Espinosa G, Serrano A, Cervera R |
International journal of molecular sciences | 2022 |
|
Recent advances in passive immunotherapies for COVID-19: The Evidence-Based approaches and clinical trials
Farhangnia P, Dehrouyeh S, Safdarian AR, Farahani SV, Gorgani M, Rezaei N, Akbarpour M, Delbandi AA |
International Immunopharmacology | 2022 |
|
The therapeutic potential of regulatory T cells in reducing cardiovascular complications in patients with severe COVID-19
Saghafi N, Rezaee SA, Momtazi-Borojeni AA, Tavasolian F, Sathyapalan T, Abdollahi E, Sahebkar A |
Life Sciences | 2022 |
|
The Role of Cytokines and Chemokines in Severe Acute Respiratory Syndrome Coronavirus 2 Infections
Hsu RJ, Yu WC, Peng GR, Ye CH, Hu S, Chong PC, Yap KY, Lee JY, Lin WC, Yu SH |
Frontiers in immunology | 2022 |
|
In silico anti-SARS-CoV-2 activities of five-membered heterocycle-substituted benzimidazoles.
Mudi PK, Mahato RK, Verma H, Panda SJ, Purohit CS, Silakari O, Biswas B |
Journal of Molecular Structure | 2022 |
|
Efficacy and safety of Guduchighana Vati in asymptomatic and mild-to-moderate cases of coronavirus disease-19: A randomized controlled pilot study.
Shukla U, Ujjaliya N, Gupta P, Khare V, Yadav B, Rai AK, Amin H, Rana R, Tripathi A, Khanduri S, Sharma BS, Chandrasekhararao B, Srikanth N, Dhiman KS |
AYU (An International Quarterly Journal of Research in Ayurveda) | 2022 |
|
A Comparison of XGBoost, Random Forest, and Nomograph for the Prediction of Disease Severity in Patients With COVID-19 Pneumonia: Implications of Cytokine and Immune Cell Profile
Hong W, Zhou X, Jin S, Lu Y, Pan J, Lin Q, Yang S, Xu T, Basharat Z, Zippi M, Fiorino S, Tsukanov V, Stock S, Grottesi A, Chen Q, Pan J |
Frontiers in Cellular and Infection Microbiology | 2022 |
|
Role of Hormones in the Pregnancy and Sex-Specific Outcomes to Infections with Respiratory Viruses
Cervantes O, Talavera IC, Every E, Coler B, Li M, Li A, Li H, Adams Waldorf K |
Immunological Reviews | 2022 |
|
Evaluation of miR-200c-3p and miR-421-5p levels during immune responses in the admitted and recovered COVID-19 subjects.
Abdolahi S, Hosseini M, Rezaei R, Mohebbi SR, Rostami-Nejad M, Mojarad EN, Mirjalali H, Yadegar A, Asadzadeh Aghdaei H, Zali MR, Baghaei K |
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases | 2022 |
|
A 6-mRNA host response classifier in whole blood predicts outcomes in COVID-19 and other acute viral infections.
Buturovic L, Zheng H, Tang B, Lai K, Kuan WS, Gillett M, Santram R, Shojaei M, Almansa R, Nieto JÁ, Muñoz S, Herrero C, Antonakos N, Koufargyris P, Kontogiorgi M, Damoraki G, Liesenfeld O, Wacker J, Midic U, Luethy R, Rawling D, Remmel M, Coyle S, Liu YE, Rao AM, Dermadi D, Toh J, Jones LM, Donato M, Khatri P, Giamarellos-Bourboulis EJ, Sweeney TE |
Scientific Reports | 2022 |
|
The Differentiation and Maintenance of SARS-CoV-2-Specific Follicular Helper T Cells
Wang Y, Tian Q, Ye L |
Frontiers in Cellular and Infection Microbiology | 2022 |
|
Risk Factors for Severity and Mortality in Adult Patients Confirmed with COVID-19 in Sierra Leone: A Retrospective Study
Tu B, Lakoh S, Xu B, Lado M, Cole R, Chu F, Hastings-Spaine S, Jalloh MB, Zheng J, Chen W, Sevalie S |
2022 | |
|
SARS-CoV-2 Infection, Sex-Related Differences, and a Possible Personalized Treatment Approach with Valproic Acid: A Review
Stakišaitis D, Kapočius L, Valančiūtė A, Balnytė I, Tamošuitis T, Vaitkevičius A, Sužiedėlis K, Urbonienė D, Tatarūnas V, Kilimaitė E, Gečys D, Lesauskaitė V |
Biomedicines | 2022 |
|
The Dynamic Role of FOXP3+ Tregs and Their Potential Therapeutic Applications During SARS-CoV-2 Infection
Xu Z, Jiang X, Dai X, Li B |
Frontiers in immunology | 2022 |
|
Can iron, zinc, copper and selenium status be a prognostic determinant in COVID-19 patients?
Engin AB, Engin ED, Engin A |
Environmental Toxicology and Pharmacology | 2022 |
|
Extensive Study on Hematological, Immunological, Inflammatory Markers, and Biochemical Profile to Identify the Risk Factors in COVID-19 Patients
Ali ET, Sajid Jabbar A, Al Ali HS, Shaheen Hamadi S, Jabir MS, Albukhaty S |
International Journal of Inflammation | 2022 |
|
Immune Cells Profiles In The Peripheral Blood Of Patients With Moderate To Severe COVID-19 And Healthy Subjects With and Without Vaccination With The Pfizer-BioNTech mRNA Vaccine
Al-Attiyah R, Safar HA, Botras L, Botras M, Al-Kandari F, Chehadeh W, Mustafa AS |
Frontiers in immunology | 2022 |
|
Effet protecteur des alpha-bloquants dans la Covid-19
Bouchareb S, Bouyahia C, Baudouin E, Neiss M, Duron E, Brunetti N, Guichardon M, Trivalle C |
2022 | |
|
Association Between Obesity and COVID-19 Disease Severity in Saudi Population
Alqahtani FY, Aleanizy FS, Mohamed RA, Al-Maflehi N, Alrfaei BM, Almangour TA, Alkhudair N, Bawazeer G, Shamlan G, Alanazi MS |
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy | 2022 |
|
PaO2 / FiO2 ratio responsiveness to prone positioning in intubated patients with severe COVID‐19: a retrospective observational study
Kawakami A, Yamakawa K, Nishioka D, Ota K, Kusaka Y, Umegaki O, Ito Y, Takasu A |
Acute Medicine & Surgery | 2022 |
|
T Lymphocytes as Targets for SARS-CoV-2
Kuklina EM |
Biochemistry (Moscow) | 2022 |
|
Intracranial complications of hypercoagulability and superinfection in the setting of COVID-19: illustrative cases
Blitz SE, McMahon JT, Chalif JI, Jarvis CA, Segar DJ, Northam WT, Chen JA, Bergmark RW, Davis JM, Yawetz S, Arnaout O |
2022 | |
|
IL-6 drives T cell death to participate in lymphopenia in COVID-19
Zhou X, Ye G, Lv Y, Guo Y, Pan X, Li Y, Shen G, He Y, Lei P |
International Immunopharmacology | 2022 |
|
A fatal SARS-coronavirus-2 induced bone marrow aplasia complicated with invasive fungal infection and severe neutropenic enterocolitis
Amanati A, Hedayati SB, Ziyaeyan M, Honar A, Dashtianeh R, Rabiei N, Saki N, Karami L |
BMC Infectious Diseases | 2022 |
|
Where do T cell subsets stand in SARS-CoV-2 infection: an update
Tarique M, Suhail M, Naz H, Muhammad N, Tabrez S, Zughaibi TA, Abuzenadah AM, Hashem AM, Shankar H, Saini C, Sharma A |
Frontiers in Cellular and Infection Microbiology | 2022 |
|
Cytokine Storm Signature in Patients with Moderate and Severe COVID-19
Kalinina O, Golovkin A, Zaikova E, Aquino A, Bezrukikh V, Melnik O, Vasilieva E, Karonova T, Kudryavtsev I, Shlyakhto E |
International journal of molecular sciences | 2022 |
|
Cellular heterogeneity in disease severity and clinical outcome: Granular understanding of immune response is key
Khare K, Pandey R |
Frontiers in immunology | 2022 |
|
Clinical Characteristics, Outcomes and Prognostic Factors for Critical Illness in Hospitalized COVID-19 Patients in Saudi Arabia: A Retrospective Cohort Study
El-Kady AM, Aldakheel FM, Allemailem KS, Almatroudi A, Dbas Alharbi R, Al Hamed H, Alsulami M, Alshehri WA, El-Ashram S, Kreys E, Mohamed K, Al-Megrin WA, Elshabrawy HA |
International journal of general medicine | 2022 |
|
Peripheral and central smell regions in COVID-19 positive patients: an MRI evaluation
Burulday V, Sayar MS, Bayar Muluk N |
Acta Radiologica | 2022 |
|
Procalcitonin as a predictive marker in COVID-19: A systematic review and meta-analysis
Kumar A, Karn E, Trivedi K, Kumar P, Chauhan G, Kumari A, Pant P, Munisamy M, Prakash J, Sarkar PG, Prasad K, Prasad A |
PloS one | 2022 |
|
In vitro Screening of Herbal Medicinal Products for Their Supportive Curing Potential in the Context of SARS-CoV-2
Tran HT, Peterburs P, Seibel J, Abramov-Sommariva D, Lamy E |
Evidence-based complementary and alternative medicine : eCAM | 2022 |
|
Crosstalk between gut microbiota and COVID-19 impacts pancreatic cancer progression
Zhang CY, Liu S, Yang M |
World journal of gastrointestinal oncology | 2022 |
|
Lymphocyte Subpopulations Associated with Neutralizing Antibody Levels of SARS-CoV-2 for COVID-19 Vaccination
Huang WT, Weng SW, Tzeng HT, Yen FC, Chiang YS, You HL |
Human vaccines | 2022 |
|
Circulating multimeric immune complexes contribute to immunopathology in COVID-19
Ankerhold J, Giese S, Kolb P, Maul-Pavicic A, Voll RE, Göppert N, Ciminski K, Kreutz C, Lother A, Salzer U, Bildl W, Welsink T, Morgenthaler NG, Grawitz AB, Emmerich F, Steinmann D, Huzly D, Schwemmle M, Hengel H, Falcone V |
Nature Communications | 2022 |
|
Implication of single nucleotide polymorphisms in Interleukin-10 gene (rs1800896 and rs1800872) with severity of COVID-19
Rizvi S, Rizvi SM, Raza ST, Abbas M, Fatima K, Zaidi ZH, Mahdi F |
2022 | |
|
COVID-19 and the antiphospholipid syndrome
Serrano M, Espinosa G, Serrano A, Cervera R |
Autoimmunity Reviews | 2022 |
|
Fatal COVID-19 is Associated with Reduced HLA-DR, CD123 or CD11c Expression on Circulating Dendritic Cells
Hasan A, Al-Ozairi E, Hassan NY, Ali S, Ahmad R, Al-Shatti N, Alshemmari S, Al-Mulla F |
Journal of inflammation research | 2022 |
|
Immunological imprint on peripheral blood in kidney transplant recipients after two doses of SARS-CoV-2 mRNA vaccination in Japan
Takiguchi S, Tomita Y, Uehara S, Tateishi K, Yamamoto N, Nakamura M |
Frontiers in Medicine | 2022 |
|
Unique cellular immune signatures of multisystem inflammatory syndrome in children.
Rajamanickam A, Nathella PK, Venkataraman A, Varadarjan P, Kannan S, Pandiarajan AN, Renji RM, Elavarasan E, Thimmaiah A, Sasidaran K, Krishnamoorthy N, Natarajan S, Ramaswamy G, Sundaram B, Putlibai S, Hissar S, Selladurai E, Uma Devi KR, Nutman TB, Babu S |
PLoS pathogens | 2022 |
|
Efficiency of nicotinamide-based supportive therapy in lymphopenia for patients with ordinary or severe COVID-19: A randomized controlled trial.
Hu Q, Zhang QY, Peng CF, Ma Z, Han YL |
Medicine | 2022 |
|
High Plasma Levels of Activated Factor VII-Antithrombin Complex Point to Increased Tissue Factor Expression in Patients with SARS-CoV-2 Pneumonia: A Potential Link with COVID-19 Prothrombotic Diathesis
Martinelli N, Rigoni AM, De Marchi S, Osti N, Donini M, Montagnana M, Castagna A, Pattini P, Udali S, De Franceschi L, Tinazzi E, Mazzi F, Moruzzi S, Argentino G, Delfino L, Sartori G, Azzini AM, Tacconelli E, Van Dreden P, Lippi G, Girelli D, Olivieri O, Friso S, Pizzolo F |
Diagnostics | 2022 |
|
Antigen-Specific T Cells and SARS-CoV-2 Infection: Current Approaches and Future Possibilities
Nova Z, Zemanek T, Botek N |
International journal of molecular sciences | 2022 |
|
Epidemiology, risk factors and prognosis of ventilator-associated pneumonia during severe COVID-19: multicenter observational study across 149 European intensive care units
Garnier M, Constantin JM, Heming N, Camous L, Ferré A, Razazi K, Lapidus N |
Anaesthesia Critical Care & Pain Medicine | 2022 |
|
Tolerogenic Dendritic Cells Induce Apoptosis-Independent T Cell Hyporesponsiveness of SARS-CoV-2-Specific T Cells in an Antigen-Specific Manner
Van Delen M, Janssens I, Dams A, Roosens L, Ogunjimi B, Berneman ZN, Derdelinckx J, Cools N |
International journal of molecular sciences | 2022 |
|
Reduced IFN-γ levels along with changes in hematologic and immunologic parameters are key to COVID-19 severity in Bangladeshi patients
Islam MM, Islam S, Ahmed R, Majumder M, Sarkar B, Himu ME, Kawser M, Hossain A, Mia MJ, Parag RR, Bulbul MR, Ahmed S, Sattar M, Biswas R, Das M, Rahman MM, Shil RK, Parial R, Chowdhury S, Das M, Noman AS, Hossain MM |
Experimental Hematology | 2022 |
|
A scoping review of regulatory T cell dynamics in convalescent COVID-19 patients – indications for their potential involvement in the development of Long COVID?
Haunhorst S, Bloch W, Javelle F, Krüger K, Baumgart S, Drube S, Lemhöfer C, Reuken P, Stallmach A, Müller M, Zielinski CE, Pletz MW, Gabriel HH, Puta C |
Frontiers in immunology | 2022 |
|
Impact of COVID-19 in solid organ transplant recipients
Danziger-Isakov L, Blumberg EA, Manuel O, Sester M |
American Journal of Transplantation | 2022 |
|
T‐cell dysfunction as a potential contributing factor in post‐COVID‐19 mucormycosis
Dandu H, Kumar M, Malhotra HS, Kumar N, Kumar N, Gupta P, Puri B, Yadav G |
Mycoses | 2022 |
|
Immunophenotyping characteristics of COVID‐19 patients: Peripheral blood CD8+ HLA‐DR+ T cells as a biomarker for mortality outcome
Mirsharif ES, Chenary MR, Bozorgmehr M, Mohammadi S, Hashemi SM, Ardestani SK, Beigmohammadi M, Abdollahi A, Sadeghipour A, Kariminia A, Tuserkani F, Ghazanfari T |
Journal of Medical Virology | 2022 |
|
Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection
Jacob K. Files, Sushma Boppana, Mildred D. Perez, Sanghita Sarkar, Kelsey E. Lowman, Kai Qin, Sarah Sterrett, Eric Carlin, Anju Bansal, Steffanie Sabbaj, Dustin M. Long, Olaf Kutsch, James Kobie, Paul Goepfert, Nathaniel Erdmann |
Journal of Clinical Investigation | 2021 |
|
The Dynamic Immunological Parameter Landscape in Coronavirus Disease 2019 Patients With Different Outcomes
G Tang, M Huang, Y Luo, W Liu, Q Lin, L Mao, S Wu, Z Xiong, H Hou, Z Sun, F Wang |
Frontiers in immunology | 2021 |
|
Immunologic memory to SARS-CoV-2 in convalescent COVID-19 patients at 1 year postinfection
H Hou, Y Zhang, G Tang, Y Luo, W Liu, C Cheng, Y Jiang, Z Xiong, S Wu, Z Sun, S Xu, X Fan, F Wang |
Journal of Allergy and Clinical Immunology | 2021 |
|
SARS-CoV-2 Induces Lymphocytopenia by Promoting Inflammation and Decimates Secondary Lymphoid Organs
Q Xiang, Z Feng, B Diao, C Tu, Q Qiao, H Yang, Y Zhang, G Wang, H Wang, C Wang, L Liu, C Wang, L Liu, R Chen, Y Wu, Y Chen |
Frontiers in immunology | 2021 |
|
Transcriptomic Signature Differences Between SARS-CoV-2 and Influenza Virus Infected Patients
S Bibert, N Guex, J Lourenco, T Brahier, M Papadimitriou-Olivgeris, L Damonti, O Manuel, R Liechti, L Götz, J Tschopp, M Quinodoz, P Vollenweider, JL Pagani, M Oddo, O Hügli, F Lamoth, V Erard, C Voide, M Delorenzi, N Rufer, F Candotti, C Rivolta, N Boillat-Blanco, PY Bochud |
Frontiers in immunology | 2021 |
|
Improving the Efficacy of Regulatory T Cell Therapy
P Baeten, LV Zeebroeck, M Kleinewietfeld, N Hellings, B Broux |
Clinical Reviews in Allergy & Immunology | 2021 |
|
Comorbidities and inflammation associated with ovarian cancer and its influence on SARS-CoV-2 infection
S Chaudhari, SD Pereira, M Asare-Warehene, R Naha, SP Kabekkodu, BK Tsang, K Satyamoorthy |
Journal of Ovarian Research | 2021 |
|
Lung histopathological findings in COVID-19 disease – a systematic review
G Pannone, VC Caponio, IS Stefano, MA Ramunno, M Meccariello, A Agostinone, MC Pedicillo, G Troiano, K Zhurakivska, T Cassano, ME Bizzoca, S Papagerakis, FM Buonaguro, S Advani, LL Muzio |
Infectious agents and cancer | 2021 |
|
Potential repurposing of the HDAC inhibitor valproic acid for patients with COVID-19
B Pitt, NR Sutton, Z Wang, SN Goonewardena, M Holinstat |
European Journal of Pharmacology | 2021 |
|
Lymphopenia, Lymphopenia-Induced Proliferation, and Autoimmunity
TT Sheu, BL Chiang |
International journal of molecular sciences | 2021 |
|
Regulatory T cells in COVID-19
H Wang, Z Wang, W Cao, Q Wu, Y Yuan, X Zhang |
Aging and disease | 2021 |
|
The role of CD4 + FoxP3 + regulatory T cells in the immunopathogenesis of COVID-19: implications for treatment
Y Wang, J Zheng, S Islam, Y Yang, Y Hu, X Chen |
International journal of biological sciences | 2021 |
|
Severe COVID-19 Is Characterized by an Impaired Type I Interferon Response and Elevated Levels of Arginase Producing Granulocytic Myeloid Derived Suppressor Cells
MJ Dean, JB Ochoa, MD Sanchez-Pino, J Zabaleta, J Garai, LD Valle, D Wyczechowska, LB Baiamonte, P Philbrook, R Majumder, RS Heide, L Dunkenberger, RP Thylur, B Nossaman, WM Roberts, AG Chapple, J Wu, C Hicks, J Collins, B Luke, R Johnson, HK Koul, CA Rees, CR Morris, J Garcia-Diaz, AC Ochoa |
Frontiers in immunology | 2021 |
|
COVID-19 in patients with systemic lupus erythematosus: lessons learned from the inflammatory disease
R Fernandez-Ruiz, JL Paredes, TB Niewold |
Translational research : the journal of laboratory and clinical medicine | 2021 |
|
Kinetics of Neutralizing Antibody Response Underscores Clinical COVID-19 Progression
Q Lei, H Hou, C Yu, Y Zhang, JL Ndzouboukou, X Lin, Z Yao, H Fu, Z Sun, F Wang, X Fan, B Xu |
Journal of Immunology Research | 2021 |
|
The cytokine storms of COVID-19, H1N1 influenza, CRS and MAS compared. Can one sized treatment fit all?
G Morris, CC Bortolasci, BK Puri, W Marx, A O'Neil, E Athan, K Walder, M Berk, L Olive, AF Carvalho, M Maes |
Cytokine | 2021 |
|
T-Helper Cell Subset Response Is a Determining Factor in COVID-19 Progression
FJ Gil-Etayo, P Suàrez-Fernández, O Cabrera-Marante, D Arroyo, S Garcinuño, L Naranjo, DE Pleguezuelo, LM Allende, E Mancebo, A Lalueza, R Díaz-Simón, E Paz-Artal, A Serrano |
Frontiers in Cellular and Infection Microbiology | 2021 |
|
HLA-DR Marks Recently Divided Antigen-Specific Effector CD4 T Cells in Active Tuberculosis Patients
R Tippalagama, A Singhania, P Dubelko, CS Arlehamn, A Crinklaw, M Pomaznoy, G Seumois, AD deSilva, S Premawansa, D Vidanagama, B Gunasena, ND Goonawardhana, D Ariyaratne, TJ Scriba, RH Gilman, M Saito, R Taplitz, P Vijayanand, A Sette, B Peters, JG Burel |
Journal of immunology (Baltimore, Md. : 1950) | 2021 |
|
Cellular and Humoral Immune Responses in Covid-19 and Immunotherapeutic Approaches
A Hasan, E Al-Ozairi, Z Al-Baqsumi, R Ahmad, F Al-Mulla |
ImmunoTargets and Therapy | 2021 |
|
Redox imbalance links COVID-19 and myalgic encephalomyelitis/chronic fatigue syndrome
BD Paul, MD Lemle, AL Komaroff, SH Snyder |
Proceedings of the National Academy of Sciences | 2021 |
|
A novel definition and treatment of hyperinflammation in COVID-19 based on purinergic signalling
D Hasan, A Shono, CK van Kalken, PJ van der Spek, EP Krenning, T Kotani |
Purinergic Signalling | 2021 |
|
CIGB-258, a peptide derived from human heat-shock protein 60, decreases hyperinflammation in COVID-19 patients
M Hernandez-Cedeño, R Venegas-Rodriguez, R Peña-Ruiz, M Bequet-Romero, R Santana-Sanchez, E Penton-Arias, G Martinez-Donato, G Guillén-Nieto, M del Carmen Dominguez-Horta |
Cell Stress and Chaperones | 2021 |
|
COVID-19 Immunobiology: Lessons Learned, New Questions Arise
A Kaklamanos, K Belogiannis, P Skendros, VG Gorgoulis, PG Vlachoyiannopoulos, AG Tzioufas |
Frontiers in immunology | 2021 |
|
When Immunity Kills: The Lessons of SARS-CoV-2 Outbreak
Y Taoufik, MG de Goër de Herve, S Corgnac, A Durrbach, F Mami-Chouaib |
Frontiers in immunology | 2021 |
|
Neutrophils and lymphopenia, an unknown axis in severe COVID-19 disease
HF Peñaloza, JS Lee, P Ray, TE Morrison |
PLoS pathogens | 2021 |
|
Perspective of HLA-G Induced Immunosuppression in SARS-CoV-2 Infection
A Lin, WH Yan |
Frontiers in immunology | 2021 |
|
Natural killer cells play an important role in virus infection control: Antiviral mechanism, subset expansion and clinical application
W Zuo, X Zhao |
Clinical Immunology | 2021 |
|
The Binary Model of Chronic Diseases Applied to COVID-19
Z Elkoshi |
Frontiers in immunology | 2021 |
|
Safety of lymphocytes immunotherapy during the COVID-19 outbreak in Wuhan, China
T Chang, S Song, D Huang, P Su, X Xiao, H Li, A Liao, W Xiang |
Archives of Gynecology and Obstetrics | 2021 |
|
Association of Clinical and Immunological Characteristics With Disease Severity and Outcomes in 211 Patients With COVID-19 in Wuhan, China
M Wang, Y Fan, Y Chai, W Cheng, K Wang, J Cao, X Hu |
Frontiers in Cellular and Infection Microbiology | 2021 |
|
T Cells: Warriors of SARS-CoV-2 Infection
P de Candia, F Prattichizzo, S Garavelli, G Matarese |
Trends in Immunology | 2021 |
|
COVID-19, cytokines, inflammation, and spices: How are they related?
AB Kunnumakkara, V Rana, D Parama, K Banik, S Girisa, S Henamayee, KK Thakur, U Dutta, P Garodia, SC Gupta, BB Aggarwal |
Life Sciences | 2021 |
|
Immunological Profiling of COVID-19 Patients with Pulmonary Sequelae
J Wu, L Tang, Y Ma, Y Li, D Zhang, Q Li, H Mei, Y Hu, JL Villarreal-Camacho, A August |
mBio | 2021 |
|
Differential alterations in peripheral lymphocyte subsets in COVID-19 patients: upregulation of double-positive and double-negative T cells
AM Zahran, ZA Zahran, YH Mady, EE Mahran, A Rashad, A Makboul, KA Nasif, AA Abdelmaksoud, O El-Badawy |
Multidisciplinary Respiratory Medicine | 2021 |
|
T cell response to SARS-CoV-2 infection in humans: A systematic review
M Shrotri, MC van Schalkwyk, N Post, D Eddy, C Huntley, D Leeman, S Rigby, SV Williams, WH Bermingham, P Kellam, J Maher, AM Shields, G Amirthalingam, SJ Peacock, SA Ismail, SR Walsh |
PloS one | 2021 |
|
The COVID-19 puzzle: deciphering pathophysiology and phenotypes of a new disease entity
MF Osuchowski, MS Winkler, T Skirecki, S Cajander, M Shankar-Hari, G Lachmann, G Monneret, F Venet, M Bauer, FM Brunkhorst, S Weis, A Garcia-Salido, M Kox, JM Cavaillon, F Uhle, MA Weigand, SB Flohé, WJ Wiersinga, R Almansa, A de la Fuente, I Martin-Loeches, C Meisel, T Spinetti, JC Schefold, C Cilloniz, A Torres, EJ Giamarellos-Bourboulis, R Ferrer, M Girardis, A Cossarizza, MG Netea, T van der Poll, JF Bermejo-Martín, I Rubio |
The lancet. Respiratory medicine | 2021 |
|
TREC/KREC Levels in Young COVID-19 Patients
MB Khadzhieva, EV Kalinina, SS Larin, DA Sviridova, AS Gracheva, JV Chursinova, VA Stepanov, IV Redkin, LS Avdeikina, AG Rumyantsev, AN Kuzovlev, LE Salnikova |
Diagnostics | 2021 |
|
Convalescent COVID-19 Patients Without Comorbidities Display Similar Immunophenotypes Over Time Despite Divergent Disease Severities
CF Chu, F Sabath, S Fibi-Smetana, S Sun, R Öllinger, E Noeßner, YY Chao, L Rinke, E Winheim, R Rad, AB Krug, L Taher, CE Zielinski |
Frontiers in immunology | 2021 |
|
What we know and still ignore on COVID‐19 immune pathogenesis and a proposal based on the experience of allergic disorders
E Maggi, BG Azzarone, GW Canonica, L Moretta |
Allergy | 2021 |
|
Immunosuppression as a Hallmark of Critical COVID-19: Prospective Study
E Kalicińska, D Szymczak, A Zińczuk, B Adamik, J Smiechowicz, T Skalec, D Nowicka-Suszko, M Biernat, A Bogucka-Fedorczuk, J Rybka, A Martuszewski, W Gozdzik, K Simon, T Wróbel |
Cells | 2021 |
|
Severe T cell hyporeactivity in ventilated COVID-19 patients correlates with prolonged virus persistence and poor outcomes
K Renner, T Schwittay, S Chaabane, J Gottschling, C Müller, C Tiefenböck, JN Salewski, F Winter, S Buchtler, S Balam, MV Malfertheiner, M Lubnow, D Lunz, B Graf, F Hitzenbichler, F Hanses, H Poeck, M Kreutz, E Orsó, R Burkhardt, T Niedermair, C Brochhausen, A Gessner, B Salzberger, M Mack |
Nature Communications | 2021 |
|
Interleukin-6, procalcitonin and neutrophil-to-lymphocyte ratio: Potential immune-inflammatory parameters to identify severe and fatal forms of COVID-19
W Sayah, I Berkane, I Guermache, M Sabri, FZ Lakhal, SY Rahali, A Djidjeli, LL mahammed, F Merah, B Belaid, L Berkani, NZ Lazli, L Kheddouci, A Kadi, M Ouali, R Khellafi, D Mekideche, A Kheliouen, RM Hamidi, S Ayoub, NB Raaf, F Derrar, M Gharnaout, I Allam, R Djidjik |
Cytokine | 2021 |
|
High-value laboratory testing for hospitalized COVID-19 patients: a review
D Cihakova, MB Streiff, SP Menez, TK Chen, NA Gilotra, ED Michos, KA Marr, AH Karaba, ML Robinson, PW Blair, MV Dioverti, WS Post, AL Cox, AA Antar |
Future Virology | 2021 |
|
Impact of presymptomatic COVID-19 on vascular and skeletal muscle function: a case study
JD Trinity, JC Craig, CC Fermoyle, AI McKenzie, MT Lewis, SH Park, MT Rondina, RS Richardson |
Journal of applied physiology | 2021 |
|
Elevated Interleukin-10 Levels in COVID-19: Potentiation of Pro-Inflammatory Responses or Impaired Anti-Inflammatory Action?
H Islam, TC Chamberlain, AL Mui, JP Little |
Frontiers in immunology | 2021 |
|
IL-6 and IL-10 as predictors of disease severity in COVID-19 patients: results from meta-analysis and regression
SK Dhar, V K, S Damodar, S Gujar, M Das |
Heliyon | 2021 |
|
A Potential Role of Interleukin 10 in COVID-19 Pathogenesis
L Lu, H Zhang, DJ Dauphars, YW He |
Trends in Immunology | 2021 |
|
Longitudinal Cytokine Profile in Patients With Mild to Critical COVID-19
L Ling, Z Chen, G Lui, CK Wong, WT Wong, RW Ng, EY Tso, KS Fung, V Chan, AC Yeung, DS Hui, PK Chan |
Frontiers in immunology | 2021 |
|
Chemokine-Based Therapeutics for the Treatment of Inflammatory and Fibrotic Convergent Pathways in COVID-19
DR Julian, MA Kazakoff, A Patel, J Jaynes, MS Willis, CC Yates |
Current Pathobiology Reports | 2021 |
|
Contribution of STAT3 to the pathogenesis of COVID-19
A Jafarzadeh, M Nemati, S Jafarzadeh |
Microbial Pathogenesis | 2021 |
|
COVID-19 and the Differences in Physiological Background Between Children and Adults and Their Clinical Consequences
L Kapustova, O PETROVICOVA, P Banovcin, M Antosova, A Bobcakova, I Urbancikova, Z Rennerova, M Jesenak |
Physiological research / Academia Scientiarum Bohemoslovaca | 2021 |
|
Infection and Immune Memory: Variables in Robust Protection by Vaccines Against SARS-CoV-2
P Ahluwalia, K Vaibhav, M Ahluwalia, AK Mondal, N Sahajpal, AM Rojiani, R Kolhe |
Frontiers in immunology | 2021 |
|
Immunological parameters associated with the severity of COVID-19 pneumonia in kidney transplant recipients
A Ozkok, N Alpay, S Alan, ND Bakan, F Soysal, H Yazici, E Ekşioğlu-Demiralp, A Yildiz |
International Urology and Nephrology | 2021 |
|
SARS-CoV-2 genome-wide T cell epitope mapping reveals immunodominance and substantial CD8 + T cell activation in COVID-19 patients
SK Saini, DS Hersby, T Tamhane, HR Povlsen, SP Hernandez, M Nielsen, AO Gang, SR Hadrup |
Science Immunology | 2021 |
|
Harnessing immunological targets for COVID-19 immunotherapy
AK Mehata, MK Viswanadh, V Priya, Vikas, MS Muthu |
Future Virology | 2021 |
|
Pronounce expression of Tim-3 and CD39 but not PD1 defines CD8 T cells in critical Covid-19 patients.
Shahbazi M, Moulana Z, Sepidarkish M, Bagherzadeh M, Rezanejad M, Mirzakhani M, Jafari M, Mohammadnia-Afrouzi M |
Microbial Pathogenesis | 2021 |
|
Prognostic bioindicators in severe COVID-19 patients.
Bergantini L, Bargagli E, d'Alessandro M, Refini RM, Cameli P, Galasso L, Scapellato C, Montagnani F, Scolletta S, Franchi F, Valente S, Bennett D, Sebastiani G, Frediani B, Dotta F |
Cytokine | 2021 |
|
A novel ratio of CD8+:B-cells as a prognostic marker of coronavirus disease 2019 patient progression and outcome.
Detsika MG, Ampelakiotou K, Grigoriou E, Psarra K, Jahaj E, Roussos C, Dimopoulou I, Orfanos SE, Tsirogianni A, Kotanidou A |
Virology | 2021 |
|
Differences of blood cells, lymphocyte subsets and cytokines in COVID-19 patients with different clinical stages: a network meta-analysis.
Yan W, Chen D, Bigambo FM, Wei H, Wang X, Xia Y |
BMC Infectious Diseases | 2021 |
|
Chest pain mimicking pulmonary embolism may be a common presentation of COVID-19 in ambulant patients without other typical features of infection.
Harrison SR, Klassen JRL, Bridgewood C, Scarsbrook A, Marzo-Ortega H, McGonagle D |
Journal of Internal Medicine | 2021 |
|
Results and Prospects of Using Activator of Hematopoietic Stem Cell Differentiation in Complex Therapy for Patients with COVID-19.
Khavinson VK, Kuznik BI, Trofimova SV, Volchkov VA, Rukavishnikova SA, Titova ON, Akhmedov TA, Trofimov AV, Potemkin VV, Magen E |
Stem Cell Reviews and Reports | 2021 |
|
Risk stratification by long non-coding RNAs profiling in COVID-19 patients.
Cheng J, Zhou X, Feng W, Jia M, Zhang X, An T, Luan M, Pan Y, Zhang S, Zhou Z, Wen L, Sun Y, Zhou C |
Journal of Cellular and Molecular Medicine | 2021 |
|
Hydroxychloroquine Effects on TLR Signalling: Underexposed but Unneglectable in COVID-19.
In 't Veld AE, Jansen MAA, Ciere LCA, Moerland M |
Journal of Immunology Research | 2021 |
|
Relationship between changes in the course of COVID-19 and ratio of neutrophils-to-lymphocytes and related parameters in patients with severe vs. common disease.
Wang K, Wang X, Du J, Liu C, Jiang Y, Zhang H, Jiang H, Fu Q |
Epidemiology and Infection | 2021 |
|
COVID-19 and Thromboinflammation: Is There a Role for Statins?
Ferrari F, Martins VM, Teixeira M, Santos RD, Stein R |
2021 | |
|
Nanocurcumin improves Treg cell responses in patients with mild and severe SARS-CoV2.
Tahmasebi S, Saeed BQ, Temirgalieva E, Yumashev AV, El-Esawi MA, Navashenaq JG, Valizadeh H, Sadeghi A, Aslani S, Yousefi M, Jadidi-Niaragh F, Adigozalou J, Ahmadi M, Roshangar L |
Life Sciences | 2021 |
|
Lymphopenia Caused by Virus Infections and the Mechanisms Beyond.
Guo Z, Zhang Z, Prajapati M, Li Y |
Viruses | 2021 |
|
Changes of Host Immunity Mediated by IFN-γ+ CD8+ T Cells in Children with Adenovirus Pneumonia in Different Severity of Illness.
Zheng R, Li Y, Chen D, Su J, Han N, Chen H, Ning Z, Xiao M, Zhao M, Zhu B |
Viruses | 2021 |
|
Cysteamine with In Vitro Antiviral Activity and Immunomodulatory Effects Has the Potential to Be a Repurposing Drug Candidate for COVID-19 Therapy.
Alonzi T, Aiello A, Petrone L, Najafi Fard S, D'Eletto M, Falasca L, Nardacci R, Rossin F, Delogu G, Castilletti C, Capobianchi MR, Ippolito G, Piacentini M, Goletti D |
Cells | 2021 |
|
Prognostic Accuracy of Cardiovascular Disease Biomarkers in Patients with COVID-19: A Diagnostic Test Accuracy Meta-Analysis.
Nasir Kansestani A, Zare ME, Zhang J |
The journal of Tehran Heart Center | 2021 |
|
Risk factors for adverse outcomes of COVID-19 patients: Possible basis for diverse responses to the novel coronavirus SARS-CoV-2.
Ghaebi M, Tahmasebi S, Jozghorbani M, Sadeghi A, Thangavelu L, Zekiy AO, Esmaeilzadeh A |
Life Sciences | 2021 |
|
Perspectives on RNA Vaccine Candidates for COVID-19.
Borah P, Deb PK, Al-Shar'i NA, Dahabiyeh LA, Venugopala KN, Singh V, Shinu P, Hussain S, Deka S, Chandrasekaran B, Jaradat DMM |
Frontiers in Molecular Biosciences | 2021 |
|
Profiling of T Cell Repertoire in SARS-CoV-2-Infected COVID-19 Patients Between Mild Disease and Pneumonia.
Chang CM, Feng PH, Wu TH, Alachkar H, Lee KY, Chang WC |
Journal of Clinical Immunology | 2021 |
|
Interactions Between Specific Immune Status of Pregnant Women and SARS-CoV-2 Infection.
Chen R, Zhang S, Su S, Ye H, Shu H |
Frontiers in Cellular and Infection Microbiology | 2021 |
|
Identifying Risk Factors for Secondary Infection Post-SARS-CoV-2 Infection in Patients With Severe and Critical COVID-19.
Guo M, Gao M, Gao J, Zhang T, Jin X, Fan J, Wang Q, Li X, Chen J, Zhu Z |
Frontiers in immunology | 2021 |
|
Accumulation of CD28null Senescent T-Cells Is Associated with Poorer Outcomes in COVID19 Patients.
Coleman MJ, Zimmerly KM, Yang XO |
Biomolecules | 2021 |
|
Effect of Vitamin D Supplementation on Muscle Status in Old Patients Recovering from COVID-19 Infection.
Caballero-García A, Pérez-Valdecantos D, Guallar P, Caballero-Castillo A, Roche E, Noriega DC, Córdova A |
2021 | |
|
Thromboinflammatory Biomarkers in COVID-19: Systematic Review and Meta-analysis of 17,052 Patients.
Chaudhary R, Garg J, Houghton DE, Murad MH, Kondur A, Chaudhary R, Wysokinski WE, McBane RD 2nd |
2021 | |
|
Immune Profile in Patients With COVID-19: Lymphocytes Exhaustion Markers in Relationship to Clinical Outcome.
Bobcakova A, Petriskova J, Vysehradsky R, Kocan I, Kapustova L, Barnova M, Diamant Z, Jesenak M |
Frontiers in Cellular and Infection Microbiology | 2021 |
|
How do older age, gender and risk groups affect protective behaviours and mental health in the COVID-19 pandemic?
Gamsızkan Z, Sungur MA, Erdemir G |
International Journal of Clinical Practice | 2021 |
|
Cytokines and Leukocytes Subpopulations Profile in SARS-CoV-2 Patients Depending on the CT Score Severity.
Rutkowska E, Kwiecień I, Żabicka M, Maliborski A, Raniszewska A, Kłos K, Urbańska W, Klajnowicz I, Rzepecki P, Chciałowski A |
Viruses | 2021 |
|
Lower mortality rate in health workers and their families infected with COVID-19 associated pneumonia in Quetta, Baluchistan.
Aslam M, Zehri MT, Mandoklel H, Kamal R, Din M |
Pakistan Journal of Medical Sciences | 2021 |
|
Two different patterns of lymphocyte alterations in critically ill COVID-19 patients.
Lafarge A, Martin JE, Longval T, Dupont T, De Jong A, Azoulay E |
Internal and Emergency Medicine | 2021 |
|
Prognostic value of elevated lactate dehydrogenase in patients with COVID-19: a systematic review and meta-analysis.
Martha JW, Wibowo A, Pranata R |
Postgraduate medical journal | 2021 |
|
Risk factors for illness severity in patients with COVID-19 pneumonia: a prospective cohort study.
Zhang N, Zhang H, Tang Y, Zhang H, Ma A, Xu F, Sun Y, Jiang L, Shan F |
International journal of medical sciences | 2021 |
|
When Does the Cytokine Storm Begin in COVID-19 Patients? A Quick Score to Recognize It.
Cappanera S, Palumbo M, Kwan SH, Priante G, Martella LA, Saraca LM, Sicari F, Vernelli C, Di Giuli C, Andreani P, Mariottini A, Francucci M, Sensi E, Costantini M, Bruzzone P, D'Andrea V, Gioia S, Cirocchi R, Tiri B |
Journal of Clinical Medicine | 2021 |
|
COVID-19 associated thrombotic thrombocytopenic purpura (TTP) ; A case series and mini-review.
Tehrani HA, Darnahal M, Vaezi M, Haghighi S |
International Immunopharmacology | 2021 |
|
Surface Proteins of SARS-CoV-2 Drive Airway Epithelial Cells to Induce IFN-Dependent Inflammation.
Anand G, Perry AM, Cummings CL, St Raymond E, Clemens RA, Steed AL |
Journal of immunology (Baltimore, Md. : 1950) | 2021 |
|
Transcriptomic characteristics and impaired immune function of patients who retest positive for SARS-CoV-2 RNA.
Wang D, Wang D, Huang M, Zheng X, Shen Y, Fu B, Zhao H, Chen X, Peng P, Zhu Q, Zhou Y, Zhang J, Tian Z, Guan W, Wang G, Wei H |
Journal of Molecular Cell Biology | 2021 |
|
COVID-19: A review of newly formed viral clades, pathophysiology, therapeutic strategies and current vaccination tasks.
Murugan C, Ramamoorthy S, Kuppuswamy G, Murugan RK, Sivalingam Y, Sundaramurthy A |
International Journal of Biological Macromolecules | 2021 |
|
Characteristics of immune function of full-term infants with different feeding patterns at the age of 3 months: a prospective cohort study.
Ma JR, Li ZH, Zhang WJ, Zhang CL, Zhang YH, Mei H, Zhuo N, Wang HY, Wu D |
Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics | 2021 |
|
A hydrated 2,3-diaminophenazinium chloride as a promising building block against SARS-CoV-2.
Mahato RK, Mahanty AK, Kotakonda M, Prasad S, Bhattacharyya S, Biswas B |
Scientific Reports | 2021 |
|
The Immunomodulatory Function of Vitamin D, with Particular Reference to SARS-CoV-2.
Caballero-García A, Noriega DC, Bello HJ, Roche E, Córdova-Martínez A |
2021 | |
|
Prognosis and antibody profiles in survivors of critical illness from COVID-19: a prospective multicentre cohort study.
Yang X, Li Z, Wang B, Pan Y, Jiang C, Zhang X, Yang Y, Zhou C, Hu C, Zhang Z, Xu H, Liao W, Vizcaychipi MP, Sanders RD, Li Y, Ma D, Peng Z |
British Journal of Anaesthesia | 2021 |
|
Preoperative ferritin and hemoglobin levels are lower in patients with a history of COVID-19 but blood loss and transfusion requirements are not increased.
Jungwirth-Weinberger A, Bendich I, Westrich GH, Su EP, Valle AGD, Boettner F |
Archives of Orthopaedic and Trauma Surgery | 2021 |
|
The effectiveness of blood routine parameters and some biomarkers as a potential diagnostic tool in the diagnosis and prognosis of Covid-19 disease.
Huyut MT, İlkbahar F |
International Immunopharmacology | 2021 |
|
COVID-19 clinical phenotypes and short-term outcomes: differences between the first and the second wave of pandemic in Italy.
Portacci A, Carpagnano GE, Tummolo MG, Santomasi C, Palma L, Fasano D, Resta E, Lozupone M, Solfrizzi V, Panza F, Resta O |
Expert Review of Respiratory Medicine | 2021 |
|
Therapeutic potential of ginger against COVID-19: Is there enough evidence?
Jafarzadeh A, Jafarzadeh S, Nemati M |
Journal of Traditional Chinese Medical Sciences | 2021 |
|
Peripheral innate and adaptive immune cells during COVID‐19: Functional neutrophils, pro‐inflammatory monocytes, and half‐dead lymphocytes
Ekşioğlu\u2010Demiralp E, Alan S, Sili U, Bakan D, Ocak İ, Yürekli R, Alpay N, Görçin S, Yıldız A |
Cytometry. Part B, Clinical cytometry | 2021 |
|
Brief Report: Virologic and Immunologic Outcomes for HIV Patients With Coronavirus Disease 2019.
Hu R, Yan H, Liu M, Tang L, Kong W, Zhu Z, Liu P, Bai W, Hu X, Ding J, Wang X, Xie N |
Journal of acquired immune deficiency syndromes (1999) | 2021 |
|
Application of a prediction model with laboratory indexes in the risk stratification of patients with COVID-19.
Ye J, Zhang X, Zhu F, Tang Y |
Experimental and therapeutic medicine | 2021 |
|
Immunotoxic role of organophosphates: An unseen risk escalating SARS-CoV-2 pathogenicity.
Rajak P, Ganguly A, Sarkar S, Mandi M, Dutta M, Podder S, Khatun S, Roy S |
Food and Chemical Toxicology | 2021 |
|
Dynamic Changes of Lymphocyte Subsets in the Course of COVID-19.
Rezaei M, Marjani M, Mahmoudi S, Mortaz E, Mansouri D |
International Archives of Allergy and Immunology | 2021 |
|
Emerging role of air pollution and meteorological parameters in COVID-19.
Zhao C, Fang X, Feng Y, Fang X, He J, Pan H |
Journal of Evidence-Based Medicine | 2021 |
|
Tranilast: a potential anti-Inflammatory and NLRP3 inflammasome inhibitor drug for COVID-19.
Saeedi-Boroujeni A, Mahmoudian-Sani MR, Nashibi R, Houshmandfar S, Tahmaseby Gandomkari S, Khodadadi A |
Immunopharmacology and Immunotoxicology | 2021 |
|
The journey of SARS-CoV-2 in human hosts: a review of immune responses, immunosuppression, and their consequences.
Alshammary AF, Al-Sulaiman AM |
Virulence | 2021 |
|
Limited TCR repertoire and ENTPD1 dysregulation mark late-stage COVID-19.
Wang N, Vuerich M, Kalbasi A, Graham JJ, Csizmadia E, Manickas-Hill ZJ, Woolley A, David C, Miller EM, Gorman K, Hecht JL, Shaefi S, Robson SC, Longhi MS |
iScience | 2021 |
|
Asymptomatic SARS-CoV-2 infection in an unvaccinated 97-year-old woman: A case report.
Georgakopoulou VE, Papalexis P, Sanos C, Bitsani A, Garmpi A, Damaskos C, Garmpis N, Gkoufa A, Chlapoutakis S, Sklapani P, Mantzouranis K, Trakas N, Spandidos DA |
Biomedical Reports | 2021 |
|
Type 1 inflammatory endotype relates to low compliance, lung fibrosis, and severe complications in COVID-19
Hasegawa T, Nakagawa A, Suzuki K, Yamashita K, Yamashita S, Iwanaga N, Tamada E, Noda K, Tomii K |
Cytokine | 2021 |
|
Association between the peripheral blood eosinophil counts and COVID-19: A meta-analysis
Huang R, Xie L, He J, Dong H, Liu T |
Medicine | 2021 |
|
ABO phenotype and clinical correlates of COVID-19 severity in hospitalized patients
Hermel DJ, Spierling Bagsic SR, Costantini CL, Mason JR, Gahvari ZJ, Saven A |
Future Science OA | 2021 |
|
Machine Learning Algorithms are Superior to Conventional Regression Models in Predicting Risk Stratification of COVID-19 Patients
Ye J, Hua M, Zhu F |
Risk Management and Healthcare Policy | 2021 |
|
Fast and Efficient Genome Editing of Human FOXP3+ Regulatory T Cells
Van Zeebroeck L, Arroyo Hornero R, Côrte-Real BF, Hamad I, Meissner TB, Kleinewietfeld M |
Frontiers in immunology | 2021 |
|
Association of HScore Parameters with Severe COVID-19: A Systematic Review and Meta-Analysis
Hossein Kazemi M, Kuhestani Dehaghi B, Roshandel E, Bonakchi H, Parkhideh S, Mehdizadeh M, Hajifathali A |
Iranian journal of medical sciences | 2021 |
|
TIM‐3 as a potential exhaustion marker in CD4+ T cells of COVID‐19 patients
Modabber Z, Shahbazi M, Akbari R, Bagherzadeh M, Firouzjahi A, Mohammadnia\u2010Afrouzi M |
Immunity, Inflammation and Disease | 2021 |
|
HLA-DRB1*04 may predict the severity of disease in a group of Iranian COVID-19 patients.
Ebrahimi S, Ghasemi-Basir HR, Majzoobi MM, Rasouli-Saravani A, Hajilooi M, Solgi G |
Human Immunology | 2021 |
|
Immunologic resilience and COVID-19 survival advantage.
Lee GC, Restrepo MI, Harper N, Manoharan MS, Smith AM, Meunier JA, Sanchez-Reilly S, Ehsan A, Branum AP, Winter C, Winter L, Jimenez F, Pandranki L, Carrillo A, Perez GL, Anzueto A, Trinh H, Lee M, Hecht JM, Martinez-Vargas C, Sehgal RT, Cadena J, Walter EA, Oakman K, Benavides R, Pugh JA, Letendre S, Steri M, Orrù V, Fiorillo E, Cucca F, Moreira AG, Zhang N, Leadbetter E, Agan BK, Richman DD, He W, Clark RA, Okulicz JF, Ahuja SK |
Journal of Allergy and Clinical Immunology | 2021 |
|
The clinical characters and prognosis of COVID-19 patients with multiple organ dysfunction.
Cui J, Yuan B, Li Y, Li Z, Yuan Y |
Medicine | 2021 |
|
D-dimer, disease severity, and deaths (3D-study) in patients with COVID-19: a systematic review and meta-analysis of 100 studies.
Varikasuvu SR, Varshney S, Dutt N, Munikumar M, Asfahan S, Kulkarni PP, Gupta P |
Scientific Reports | 2021 |
|
Peptide Drug Thymalin Regulates Immune Status in Severe COVID-19 Older Patients
Kuznik B, Khavinson V, Shapovalov K, Linkova N, Lukyanov S, Smolyakov Y, Tereshkov P, Shapovalov Y, Konnov V, Tsybikov N |
Advances in Gerontology | 2021 |
|
COVID-19 coagulopathy and antiphospholipid syndrome
Serrano M, Espinosa G, Cervera R, Serrano A |
Revista Colombiana de Reumatología | 2021 |
|
Impact of Chronic HIV Infection on SARS-CoV-2 Infection, COVID-19 Disease and Vaccines
Yang Y, Iwasaki A |
Current HIV/AIDS Reports | 2021 |
|
Peripheral T cell lymphopenia in COVID-19: potential mechanisms and impact
Zhang S, Asquith B, Szydlo R, Tregoning JS, Pollock KM |
2021 | |
|
High levels of SARS-CoV-2 specific T-cells with restricted functionality in severe course of COVID-19
David Schub, Verena Klemis, Sophie Schneitler, Janine Mihm, Philipp M. Lepper, Heinrike Wilkens, Robert Bals, Hermann Eichler, Barbara C. Gärtner, Sören L. Becker, Urban Sester, Martina Sester, Tina Schmidt |
JCI Insight | 2020 |
|
The pathophysiology of SARS-CoV-2: A suggested model and therapeutic approach
G Morris, CC Bortolasci, BK Puri, L Olive, W Marx, A O'Neil, E Athan, A Carvalho, M Maes, K Walder, M Berk |
Life Sciences | 2020 |
|
Preventing the development of severe CoVID 19 by modifying immunothrombosis
G Morris, CC Bortolasci, BK Puri, L Olive, W Marx, A O'Neil, E Athan, A Carvalho, M Maes, K Walder, M Berk |
Life Sciences | 2020 |
|
Tyrosine Kinase Inhibitors Play an Antiviral Action in Patients Affected by Chronic Myeloid Leukemia: A Possible Model Supporting Their Use in the Fight Against SARS-CoV-2
S Galimberti, M Petrini, C Baratè, F Ricci, S Balducci, S Grassi, F Guerrini, E Ciabatti, S Mechelli, AD Paolo, C Baldini, L Baglietto, L Macera, PG Spezia, F Maggi |
Frontiers in Oncology | 2020 |
|
The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system
F Coperchini, L Chiovato, L Croce, F Magri, M Rotondi |
Cytokine & Growth Factor Reviews | 2020 |
|
Association between markers of immune response at hospital admission and COVID‐19 disease severity and mortality: A meta‐analysis and meta‐regression
J Khinda, NZ Janjua, S Cheng, ER Heuvel, P Bhatti, M Darvishian |
Journal of Medical Virology | 2020 |
|
Sharing CD4+ T Cell Loss: When COVID-19 and HIV Collide on Immune System
X Peng, J Ouyang, S Isnard, J Lin, B Fombuena, B Zhu, JP Routy |
Frontiers in immunology | 2020 |
|
A Longitudinal Study of Immune Cells in Severe COVID-19 Patients
D Payen, M Cravat, H Maadadi, C Didelot, L Prosic, C Dupuis, MR Losser, MD Bittencourt |
Frontiers in immunology | 2020 |
|
A 21st Century Evil: Immunopathology and New Therapies of COVID-19
TF Silva, F Tomiotto-Pellissier, RA Sanfelice, MD Gonçalves, BT da Silva Bortoleti, MB Detoni, AC Rodrigues, AC Carloto, VM Concato, E da Silva Siqueira, IN Costa, WR Pavanelli, I Conchon-Costa, MM Miranda-Sapla |
Frontiers in immunology | 2020 |
|
Severe COVID-19: what have we learned with the immunopathogenesis?
B Bordallo, M Bellas, AF Cortez, M Vieira, M Pinheiro |
2020 | |
|
COVID‐19 and Treg/Th17 imbalance: Potential relationship to pregnancy outcomes
KP Muyayalo, DH Huang, SJ Zhao, T Xie, G Mor, AH Liao |
American Journal of Reproductive Immunology | 2020 |
|
Deciphering the TCR Repertoire to Solve the COVID-19 Mystery
L Gutierrez, J Beckford, H Alachkar |
Trends in Pharmacological Sciences | 2020 |
|
Harnessing Memory NK Cell to Protect Against COVID-19
S Soleimanian, R Yaghobi |
Frontiers in pharmacology | 2020 |
|
Understanding immunopathological fallout of human coronavirus infections including COVID‐19: Will they cross the path of rheumatologists?
J Kabeerdoss, D Danda |
International Journal of Rheumatic Diseases | 2020 |
|
Inflammation, Immunity and Immunogenetics in COVID-19: A Narrative Review
M Lingeswaran, T Goyal, R Ghosh, S Suri, P Mitra, S Misra, P Sharma |
Indian Journal of Clinical Biochemistry | 2020 |
|
Dynamic profiles of SARS-Cov-2 infection from five Chinese family clusters in the early stage of the COVID-19 pandemic
XK, J Geng, T Zhang, B Wang, AZ Wu, D Xiao, ZH Zhang, CF Liu, L Wang, XM Jiang, YC Fan |
Scientific Reports | 2020 |
|
Mild Cytokine Elevation, Moderate CD4+ T Cell Response and Abundant Antibody Production in Children with COVID-19
R Jia, X Wang, P Liu, X Liang, Y Ge, H Tian, H Chang, H Zhou, M Zeng, J Xu |
Virologica Sinica | 2020 |
|
Emerging evidence of a COVID-19 thrombotic syndrome has treatment implications
JT Merrill, D Erkan, J Winakur, JA James |
Nature Reviews Rheumatology | 2020 |
|
A systematic meta‐analysis of immune signatures in patients with COVID‐19
K Liu, T Yang, XF Peng, SM Lv, X Ye, TS Zhao, JC Li, ZJ Shao, QB Lu, JY Li, W Liu |
Reviews in Medical Virology | 2020 |
|
Deciphering SARS-CoV-2 Virologic and Immunologic Features
G Lebeau, D Vagner, É Frumence, F Ah-Pine, X Guillot, E Nobécourt, L Raffray, P Gasque |
International journal of molecular sciences | 2020 |
|
Understanding the immunopathogenesis of COVID-19: Its implication for therapeutic strategy
Y Shimizu |
World journal of clinical cases | 2020 |
|
Challenges in the Production of Convalescent Hyperimmune Plasma in the Age of COVID-19
M Franchini, CD Fante, C Klersy, C Glingani, E Percivalle, F Baldanti, C Perotti |
Seminars in thrombosis and hemostasis | 2020 |
|
Early changes in laboratory parameters are predictors of mortality and ICU admission in patients with COVID-19: a systematic review and meta-analysis
S Kiss, N Gede, P Hegyi, D Németh, M Földi, F Dembrovszky, B Nagy, MF Juhász, K Ocskay, N Zádori, Z Molnár, A Párniczky, PJ Hegyi, Z Szakács, G Pár, B Erőss, H Alizadeh |
Medical Microbiology and Immunology | 2020 |
|
Preventing Mortality in COVID-19 Patients: Which Cytokine to Target in a Raging Storm?
L Lu, H Zhang, M Zhan, J Jiang, H Yin, DJ Dauphars, SY Li, Y Li, YW He |
Frontiers in Cell and Developmental Biology | 2020 |
|
Antibody tests for identification of current and past infection with SARS-CoV-2.
Deeks JJ, Dinnes J, Takwoingi Y, Davenport C, Spijker R, Taylor-Phillips S, Adriano A, Beese S, Dretzke J, Ferrante di Ruffano L, Harris IM, Price MJ, Dittrich S, Emperador D, Hooft L, Leeflang MM, Van den Bruel A |
The Cochrane Database of Systematic Reviews | 2020 |
|
COVID-19 related lung pathology: old patterns in new clothing?
Nicholson AG, Osborn M, Devaraj A, Wells AU |
Histopathology | 2020 |
|
Bilevel and continuous positive airway pressure and factors linked to all-cause mortality in COVID-19 patients in an intermediate respiratory intensive care unit in Italy.
Carpagnano GE, Buonamico E, Migliore G, Resta E, Di Lecce V, de Candia ML, Solfrizzi V, Panza F, Resta O |
Expert Review of Respiratory Medicine | 2020 |
|
A Potential Bioelectromagnetic Method to Slow Down the Progression and Prevent the Development of Ultimate Pulmonary Fibrosis by COVID-19.
Masaud SM, Szasz O, Szasz AM, Ejaz H, Anwar RA, Szasz A |
Frontiers in immunology | 2020 |
|
Hypoxia inducible factor-1 protects against COVID-19: A hypothesis.
Afsar B, Kanbay M, Afsar RE |
Medical Hypotheses | 2020 |
|
SARS-CoV-2: An immunogenetics call to arms.
Clark B, Poulton K |
International Journal of Immunogenetics | 2020 |
|
Cardiovascular Disease and SARS-CoV-2: the Role of Host Immune Response Versus Direct Viral Injury.
Biscetti F, Rando MM, Nardella E, Cecchini AL, Bruno P, Landolfi R, Flex A |
International journal of molecular sciences | 2020 |
|
GM-CSF Neutralization With Lenzilumab in Severe COVID-19 Pneumonia: A Case-Cohort Study.
Temesgen Z, Assi M, Shweta FNU, Vergidis P, Rizza SA, Bauer PR, Pickering BW, Razonable RR, Libertin CR, Burger CD, Orenstein R, Vargas HE, Palraj R, Dababneh AS, Chappell G, Chappell D, Ahmed O, Sakemura R, Durrant C, Kenderian SS, Badley AD |
Mayo Clinic Proceedings | 2020 |
|
Gender-associated difference following COVID-19 virus infection: Implications for thymosin alpha-1 therapy.
Li X, Liu L, Yang Y, Yang X, Wang C, Li Y, Ge Y, Shi Y, Lv P, Zhou H, Luo P, Huang S |
International Immunopharmacology | 2020 |
|
Two important controversial risk factors in SARS-CoV-2 infection: Obesity and smoking.
Engin AB, Engin ED, Engin A |
Environmental Toxicology and Pharmacology | 2020 |
|
Prealbumin as a Predictor of Prognosis in Patients With Coronavirus Disease 2019.
Luo Y, Xue Y, Mao L, Yuan X, Lin Q, Tang G, Song H, Wang F, Sun Z |
Frontiers in Medicine | 2020 |
|
Endpoints for randomized controlled clinical trials for COVID-19 treatments.
Dodd LE, Follmann D, Wang J, Koenig F, Korn LL, Schoergenhofer C, Proschan M, Hunsberger S, Bonnett T, Makowski M, Belhadi D, Wang Y, Cao B, Mentre F, Jaki T |
Clinical trials (London, England) | 2020 |
|
Hemostatic Changes in Patients with COVID-19: A Meta-Analysis with Meta-Regressions.
Di Minno MND, Calcaterra I, Lupoli R, Storino A, Spedicato GA, Maniscalco M, Di Minno A, Ambrosino P |
Journal of Clinical Medicine | 2020 |
|
Immune Parameters and COVID-19 Infection - Associations With Clinical Severity and Disease Prognosis.
Jesenak M, Brndiarova M, Urbancikova I, Rennerova Z, Vojtkova J, Bobcakova A, Ostro R, Banovcin P |
Frontiers in Cellular and Infection Microbiology | 2020 |
|
Remodeling of the Immune Response With Aging: Immunosenescence and Its Potential Impact on COVID-19 Immune Response.
Cunha LL, Perazzio SF, Azzi J, Cravedi P, Riella LV |
Frontiers in immunology | 2020 |
|
A Controllable Inflammatory Response and Temporary Abnormal Coagulation in Moderate Disease of COVID-19 in Wuhan, China.
Liu Y, Zhang X, Qiao J, Gong R, You Q, Sun J, Liu W, Sun B |
Journal of clinical medicine research | 2020 |
|
Serum KL-6 level is a useful biomarker for evaluating the severity of coronavirus disease 2019.
Awano N, Inomata M, Kuse N, Tone M, Takada K, Muto Y, Fujimoto K, Akagi Y, Mawatari M, Ueda A, Izumo T |
Respiratory Investigation | 2020 |
|
Immune-Mediated Coagulopathy in COVID-19 Infection.
Vadasz Z, Brenner B, Toubi E |
Seminars in thrombosis and hemostasis | 2020 |
|
Baseline characteristics and outcomes of COVID-19 patients admitted to a Respiratory Intensive Care Unit (RICU) in Southern Italy.
Di Lecce V, Carpagnano GE, Pierucci P, Quaranta VN, Barratta F, Zito A, Buonamico E, Resta O |
Multidisciplinary Respiratory Medicine | 2020 |
|
Analysis of the molecular mechanism of Pudilan (PDL) treatment for COVID-19 by network pharmacology tools.
Kong Q, Wu Y, Gu Y, Lv Q, Qi F, Gong S, Chen X |
Biomedicine & Pharmacotherapy | 2020 |
|
The vascular endothelium: the cornerstone of organ dysfunction in severe SARS-CoV-2 infection.
Pons S, Fodil S, Azoulay E, Zafrani L |
Critical Care | 2020 |
|
Development and external validation of a prediction risk model for short-term mortality among hospitalized U.S. COVID-19 patients: A proposal for the COVID-AID risk tool.
Hajifathalian K, Sharaiha RZ, Kumar S, Krisko T, Skaf D, Ang B, Redd WD, Zhou JC, Hathorn KE, McCarty TR, Bazarbashi AN, Njie C, Wong D, Shen L, Sholle E, Cohen DE, Brown RS Jr, Chan WW, Fortune BE |
PloS one | 2020 |
|
Predictors of Severity and Co-Infection Resistance Profile in COVID-19 Patients: First Report from Upper Egypt.
Ramadan HK, Mahmoud MA, Aburahma MZ, Elkhawaga AA, El-Mokhtar MA, Sayed IM, Hosni A, Hassany SM, Medhat MA |
Infection and drug resistance | 2020 |
|
Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines.
Flanagan KL, Best E, Crawford NW, Giles M, Koirala A, Macartney K, Russell F, Teh BW, Wen SC |
Frontiers in immunology | 2020 |
|
The effect of environmental pollution on immune evasion checkpoints of SARS-CoV-2.
Engin AB, Engin ED, Engin A |
Environmental Toxicology and Pharmacology | 2020 |
|
Immune Correlates of COVID-19 Control.
Poonia B, Kottilil S |
Frontiers in immunology | 2020 |
|
Thymalin: Activation of Differentiation of Human Hematopoietic Stem Cells.
Khavinson VK, Linkova NS, Kvetnoy IM, Polyakova VO, Drobintseva AO, Kvetnaia TV, Ivko OM |
Bulletin of Experimental Biology and Medicine | 2020 |
|
Dynamic changes of T-lymphocyte subsets and the correlations with 89 patients with coronavirus disease 2019 (COVID-19).
Huang M, Wang Y, Ye J, Da H, Fang S, Chen L |
Annals of translational medicine | 2020 |
|
Disseminated Herpes Zoster During COVID-19.
Voisin O, Deluca N, Mahé A, Lelorc'h E, Hubert S, Ménage E, Borie MF, Azria P, Fite C, Pilmis B, Mourad JJ |
Infectious Diseases in Clinical Practice | 2020 |
|
COVID-19: Discovery, diagnostics and drug development.
Asselah T, Durantel D, Pasmant E, Lau G, Schinazi RF |
Journal of Hepatology | 2020 |
|
Emergency Department Management of COVID-19: An Evidence-Based Approach.
McManus NM, Offman R, Oetman JD |
The western journal of emergency medicine | 2020 |
|
Virulence and pathogenesis of SARS-CoV-2 infection in rhesus macaques: A nonhuman primate model of COVID-19 progression.
Zheng H, Li H, Guo L, Liang Y, Li J, Wang X, Hu Y, Wang L, Liao Y, Yang F, Li Y, Fan S, Li D, Cui P, Wang Q, Shi H, Chen Y, Yang Z, Yang J, Shen D, Cun W, Zhou X, Dong X, Wang Y, Chen Y, Dai Q, Jin W, He Z, Li Q, Liu L |
PLoS pathogens | 2020 |
|
Tocilizumab: The Key to Stop Coronavirus Disease 2019 (COVID-19)-Induced Cytokine Release Syndrome (CRS)?
Liu D, Zhang T, Wang Y, Xia L |
Frontiers in Medicine | 2020 |
|
Peripheral Blood Immune Profiling of Convalescent Plasma Donors Reveals Alterations in Specific Immune Subpopulations Even at 2 Months Post SARS-CoV-2 Infection.
Orologas-Stavrou N, Politou M, Rousakis P, Kostopoulos IV, Ntanasis-Stathopoulos I, Jahaj E, Tsiligkeridou E, Gavriatopoulou M, Kastritis E, Kotanidou A, Dimopoulos MA, Tsitsilonis OE, Terpos E |
Viruses | 2020 |
|
Interleukine-6 in critically ill COVID-19 patients: A retrospective analysis.
Gorham J, Moreau A, Corazza F, Peluso L, Ponthieux F, Talamonti M, Izzi A, Nagant C, Ndieugnou Djangang N, Garufi A, Creteur J, Taccone FS |
PloS one | 2020 |
|
Clinical and laboratory features of COVID-19: Predictors of severe prognosis.
Bastug A, Bodur H, Erdogan S, Gokcinar D, Kazancioglu S, Kosovali BD, Ozbay BO, Gok G, Turan IO, Yilmaz G, Gonen CC, Yilmaz FM |
International Immunopharmacology | 2020 |
|
Biomarkers and outcomes of COVID-19 hospitalisations: systematic review and meta-analysis.
Malik P, Patel U, Mehta D, Patel N, Kelkar R, Akrmah M, Gabrilove JL, Sacks H |
2020 | |
|
SARS-CoV-2-induced immunodysregulation and the need for higher clinical suspicion for co-infection and secondary infection in COVID-19 patients.
Parrill A, Tsao T, Dong V, Huy NT |
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi | 2020 |
|
Immunotherapy for ANCA-associated vasculitis during the COVID-19 pandemic
Gapud EJ, Kronbichler A, Gauckler P, Geetha D |
European Journal of Rheumatology | 2020 |
|
Preparedness of pharmacists to respond to the emergency of the COVID-19 pandemic in Brazil: a comprehensive overview.
Parreiras Martins MA, Fonseca de Medeiros A, Dias Carneiro de Almeida C, Moreira Reis AM |
2020 | |
|
Elevated D-dimer levels on admission are associated with severity and increased risk of mortality in COVID-19: A systematic review and meta-analysis.
Gungor B, Atici A, Baycan OF, Alici G, Ozturk F, Tugrul S, Asoglu R, Cevik E, Sahin I, Barman HA |
The American Journal of Emergency Medicine | 2020 |
|
Ferritin in the coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis.
Cheng L, Li H, Li L, Liu C, Yan S, Chen H, Li Y |
Journal of Clinical Laboratory Analysis | 2020 |
|
Factors associated with disease severity and mortality among patients with COVID-19: A systematic review and meta-analysis.
Chidambaram V, Tun NL, Haque WZ, Majella MG, Sivakumar RK, Kumar A, Hsu AT, Ishak IA, Nur AA, Ayeh SK, Salia EL, Zil-E-Ali A, Saeed MA, Sarena APB, Seth B, Ahmadzada M, Haque EF, Neupane P, Wang KH, Pu TM, Ali SMH, Arshad MA, Wang L, Baksh S, Karakousis PC, Galiatsatos P |
PloS one | 2020 |
|
Population Difference in Allele Frequency of HLA-C*05 and Its Correlation with COVID-19 Mortality.
Sakuraba A, Haider H, Sato T |
Viruses | 2020 |
|
Herbal immune-boosters: Substantial warriors of pandemic Covid-19 battle.
Khanna K, Kohli SK, Kaur R, Bhardwaj A, Bhardwaj V, Ohri P, Sharma A, Ahmad A, Bhardwaj R, Ahmad P |
Phytomedicine : international journal of phytotherapy and phytopharmacology | 2020 |
|
Interleukin-6 receptor blocking with intravenous tocilizumab in COVID-19 severe acute respiratory distress syndrome: A retrospective case-control survival analysis of 128 patients
Canziani LM, Trovati S, Brunetta E, Testa A, De Santis M, Bombardieri E, Guidelli G, Albano G, Folci M, Squadroni M, Beretta GD, Ciccarelli M, Castoldi M, Lleo A, Aghemo A, Vernile L, Malesci A, Omodei P, Angelini C, Badalamenti S, Cecconi M, Cremonesi A, Selmi C |
Journal of Autoimmunity | 2020 |
|
T cell immunobiology and cytokine storm of COVID‐19
Luo X, Zhu Y, Mao J, Du R |
Scandinavian Journal of Immunology | 2020 |
|
Potential of regulatory T-cell-based therapies in the management of severe COVID-19.
Stephen-Victor E, Das M, Karnam A, Pitard B, Gautier JF, Bayry J |
European Respiratory Journal | 2020 |
|
A role for human leucocyte antigens in the susceptibility to SARS-Cov-2 infection observed in transplant patients.
Poulton K, Wright P, Hughes P, Savic S, Welberry Smith M, Guiver M, Morton M, van Dellen D, Tholouli E, Wynn R, Clark B |
International Journal of Immunogenetics | 2020 |
|
Ferritin levels in patients with COVID‐19: A poor predictor of mortality and hemophagocytic lymphohistiocytosis
Feld J, Tremblay D, Thibaud S, Kessler A, Naymagon L |
International Journal of Laboratory Hematology | 2020 |
|
Cytokine Storm in COVID-19: “When You Come Out of the Storm, You Won’t Be the Same Person Who Walked in”
Castelli V, Cimini A, Ferri C |
Frontiers in immunology | 2020 |
|
Obesity is Associated with Worse Outcomes in COVID‐19: Analysis of Early Data from New York City
Hajifathalian K, Kumar S, Newberry C, Shah S, Fortune B, Krisko T, Ortiz\u2010Pujols S, Zhou XK, Dannenberg AJ, Kumar R, Sharaiha RZ |
Obesity (Silver Spring, Md.) | 2020 |
|
Diagnosing COVID‐19 in the Emergency Department: A Scoping Review of Clinical Examinations, Laboratory Tests, Imaging Accuracy, and Biases
Carpenter CR, Mudd PA, West CP, Wilber E, Wilber ST |
Academic Emergency Medicine | 2020 |
|
Delayed virus‐specific antibody responses associate with COVID‐19 mortality
Wang F, Yao Y, Hou H, Wu S, Guo C, Zhou H, Liu Z, Sun Z |
Allergy | 2020 |
|
Pulmonary surfactant: an immunological perspective
ZC Chroneos, Z Sever-Chroneos, VL Shepherd |
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology | 2009 |
