March 13, 2025: Revised the guaranteed reviews and rewards section by adding more details
January 31, 2025: Added information regarding YPSA Guaranteed Review to "Review of manuscripts"
December 15, 2024: Added Public Health to create Clinical Research and Public Health category; revised description of Research category.
December 2: Added announcement of publication fee change beginning January 1, 2025.
November 13, 2024: Dual-Journal Submission is live.
November 6, 2024: Added link to NIH race and ethnicity guideline revisions.
November 1, 2024: Added Dual-Journal Submission option.
October 9, 2024: Added guidelines for generative AI technologies.
October 1, 2024: Revised manuscript content for Research letter category.
September 1, 2024: Added Research Letter category; option to transfer reviews from other journals. Also made organizational/cosmetic revisions.
March 7, 2024: Added Physician-Scientist Development as a submission category.
December 13, 2023: Added requirement for “Sex as a biological variable” paragraph (effective January 1, 2024).
November 14, 2023: Updated the publication fee for 2024.
October 24, 2023: Revised "Graphs and images" section.
October 9, 2023: Revised to require uploading of supporting data values at first submission; and publication of blot gel images if manuscript is accepted.
September 15, 2023: Reformatted "Data availability" section.
July 13, 2023: Added links to "How to prepare tables" and "How to prepare Supporting data files."
July 6, 2023: Updated policy for ASCI member guaranteed review limit to 1.
April 6, 2023: February 20, 2023: Added requirements for Data availability subsection and Supporting data values; updated guideline for repeated use of figures or panels.
January 13, 2023: Updated publication fee.
November 21, 2022: Added notice that effective January 1, 2023, the publication fee increases from $4,100 to $4,500.
November 1, 2022: Added "Misconduct allegations" to COI.
July 18, 2022: Added note indicating ASCI member guaranteed review limit changing from 3 to 1 in 2023.
June 19, 2022: Updated patient photograph policy.
June 13, 2022: Updated blot/gel policy language and added cover image submission instructions.
April 21, 2022: Added "Submissions" section under Editorial policies and practices.
March 30, 2022: Changed email address for Video abstracts from editorial@insight.jci.org to production@insight.jci.org.
March 10, 2022: Updated so only current publication fee is shown (became effective with January 2022); added language about requests for reduced fee.
December 20, 2021: Clarified Copyright section.
October 4, 2021: Added notification that publication fee will change from $3,650 to $4,100 beginning with the January 4, 2022 issue.
September 15, 2021: Clarified text regarding reviewer suggestions and exclusion.
August 31, 2021: Added "Demographic reporting" section under "Experimental design."
August 2021: Revised "Author information" page to "Author information center"; added kiosks for first and revised submissions.
June 7, 2021: Content maintenance.
May 13, 2021: Revised Conflict of interest wording for Editors, authors, reviewers.
November 12, 2020: Introduced policy for shared first authors: explanation of ordering must appear in Author contributions; changed word limit for figure legends from 400 to 300.
November 10, 2020: Revised style for references with 3 or more authors to list only the first author plus ", et al."
August 2, 2020: Removed transfer from other top-tier journals.
July 1, 2020: Updated to indicate that all accepted manuscripts hereafter are published under a CC BY license.
June 3, 2020: Added medRxiv to Preprints.
April 28, 2020: Revised "Prior publication" to state that preprints are acceptable; removed all other items from this section; added bookmark to References.
August 29, 2019: Deleted requirement to define abbreviations in table legends.
March 21, 2019: For preprints and bioRxiv, specified research manuscripts.
February 11, 2019: Added requirement for Word/RTF file for first submission.
February 7, 2019: Added preprints to the References section.
February 5, 2019: Added embargo information to In-Press preview section.
January 2, 2019: Added Reviewer Rewards and In-Press previews.
January 1, 2019: Changed publication fee from $3,500 to $3,650.
October 4, 2018: Added bioRxiv option to Manuscript submission section.
June 7, 2018: Added Graphical abstracts.
March 27, 2018: Added to Publication proofs that substantive changes will not be accepted.
June 30, 2017: Added preference for PDF submissions preference that figure and corresponding legend appear on same page.
March 22, 2017: Revised to include PubMed and Web of Science in Indexing information.
February 1, 2017: Clarified application of CC BY copyright licenses for authors of research articles whose funders require it.
January 7, 2017: Changed publication fee from $3,000 to $3,500.
December 21, 2016: Removed Submission fee section.
October 7, 2016: Added Indexing information.
October 6, 2016: Revised to show inclusion in PubMed Central.
October 3, 2016: Added external transfer option.
July 26, 2016: Figure instructions page revised to specify 600 ppi for all figures.
May 27, 2016: Updated "Depositing in PubMed Central" to indicate that JCI Insight has applied for inclusion.
May 25, 2016: Added text prohibiting reuse of data within article.
April 15, 2016: Added link to new License information page.
April 6, 2016: Added recommendation to use EndNote to style references.
March 1, 2016: Added requirement that quantitative data be shown as dot or box and whisker plots (no plunger plots).
January 6, 2016: Added requirement to define abbreviations in table legends.
January 5, 2016: Deleted open-to-submissions date and updated timing of figure file upload requirement.
December 15, 2024: Added Public Health to create Clinical Research and Public Health category and revised instructions; revised Research category description.
November 13, 2024: Dual-Journal Submissionis live.
November 1, 2024: Added Dual-Journal Submission option.
September 1, 2024: Added Research Letter category; option to transfer reviews from other journals; reorganized manuscript preparation and submission sections.
March 7, 2024: Added Physician-Scientist Development as a submission category.
December 13, 2023: Added requirement for "Sex as a biological variable" paragraph starting January 1, 2024.
October 25, 2023: Revised to state that uncut blots and gels will be published for any accepted manuscript effective January 1, 2024; and to require supporting data values file at first submission.
October 3, 2023: Changed requirement for quantitative graph presentation to occur at first submission.
July 13, 2023: Added links to "How to prepare tables."
June 1, 2023: Provided alternate URL for CONSORT checklist.
April 6, 2023: Added requirement for Data Availability paragraph.
December 1, 2024: Revised Clinical Medicine to Clinical Research and Public Health and changed description.
October 1, 2024: Revised content for Research Letter category.
September 1: Added Research Letter category; reorganized main sections.
March 7, 2024: Added Physician-Scientist Development as a submission category.
December 13, 2023: Added requirement for "Sex as a biological variable" paragraph starting January 1, 2024.
October 26, 2023: Revised to state that uncut blots and gels will be published for any accepted manuscript effective January 1, 2024; and to require supporting data values file at first submission.
July 12, 2023: Added links to "How to prepare tables" and "How to prepare Supprting data values."
April 6, 2023: Added requirement for Supporting Data Values and Data Availability paragraph; and policy on repeated images.
June 19, 2022: Updated patient photograph requirement.
December 15, 2024: Changed Clinical Medicine to Clinical Research and Public Health throughout.
December 2, 2024: Added announcement of publication fee change beginning January 1, 2025.
November 1, 2024: Added Dual-Journal Submission option.
October 9, 2024: Added guidelines for AI technologies.
September 1, 2024: Added Research Letter fee and option to transfer of reviews from other journals.
February 7, 2024: Added publication fee for new Physician-Scientist Development category and updated fee for all other research.
November 14, 2023: Updated publication fee for 2024.
July 6, 2023: Updated ASCI member guarantee limit to 1.
November 1,2022: Added "Misconduct allegations" section.
July 18, 2022: Added note indicating ASCI member guaranteed review limit changing from 3 to 1 in 2023.
March 10, 2021: Updated to show only current publication fee; added language about requests for fee reduction.
December 20, 2021: Clarified "Copyright and access"t language.
Octobert 4, 2021: Added notification of change in publication fee from $3,650 to $4,100.
September 15, 2021: Clarified text regarding reviewer suggestions and exclusions.
July 19, 2021: Added language regarding Proofig.
June 21, 2021: Revisions throughout, including clarifications regarding corresponding author definition, ASCI member guaranteed review, and scientific misconduct; updating conflict-of-interest wording and publishing schedule; and copyedits.
November 19, 2020: Added policy requiring description of method used for assigning authorship order among co–first authors.
August 27, 2020: Updated to show August 20, 2020, issue is first CC BY–only issue.
July 1, 2020: Updated to show CC BY 4.0 license for all articles.
June 12, 2019: Updated indexing resources.
January 2, 2019: Added Reviewer Rewards, ASCI guaranteed review benefit, and In-Press Previews.
January 1, 2019: Changed publication fee from $3500 to $3650.