In this video collection, authors of findings published in JCI Insight present personally guided tours of their results. The journal accepts video submissions from authors of recently accepted manuscripts. Instructions can be found on the Author's Take Guidelines page.
In this episode, Michel Bouvier explains the present study aimed at testing pharmacological chaperones in humanized MC4R mouses model as potential therapeutic treatment of melanocortin type 4 receptor linked obesity.
The age-related pro-repair function of Treg cells following influenza infection is determined by cell-autonomous mechanisms.
In this episode, Marisa Zallocchi explains how treatment with quinoxaline derivatives protects from aminoglycoside- and cisplatin-hearing loss by NF-kB inhibition.
In this episode, Jennifer Alexander-Brett and colleagues explain that epithelial IL-33 co-secretion with exosomes is blocked by inhibitors of the neutral sphingomyelinase-dependent multivesicular endosome pathway, which reduces type-2 inflammation in airway disease.
In this episode, Alexander Dietrich and Christian Schremmer explain how TRPV4 is essential for alveolar epithelial function and protects from ischemia-reperfusion induced lung edema.