Isolation and characterization of mouse nasal-associated lymphoid tissue

H Asanuma, AH Thompson, T Iwasaki, Y Sato… - Journal of …, 1997 - Elsevier
A method for isolation of mouse nasal-associated lymphoid tissue (NALT), which is a
principal mucosal lymphoid tissue of the respiratory tract in rodents, was developed. The
paired lymphoid organs could be separated from the upper jaw by peeling away the palate
where NALT was localized bilaterally on the posterior side. About 3× 105 lymphocytes could
be obtained from one NALT fragment. The NALT lymphocyte fraction from normal BALB/c
mice contained T-and B-cells in about equal numbers, and contained about 4 times as many …