[HTML][HTML] Identification and characterization of a gene encoding a gut-enriched Krüppel-like factor expressed during growth arrest

JM Shields, RJ Christy, VW Yang - Journal of Biological Chemistry, 1996 - ASBMB
A cDNA clone, named gut-enriched Krüppel-like factor (GKLF), was isolated from an NIH
3T3 library using a probe encoding the zinc finger region of the immediate-early
transcription factor zif/268. The deduced GKLF amino acid sequence contains three tandem
zinc fingers that are related to members of the Krüppel family of transcription factors. By
indirect immunofluorescence, GKLF is localized to the cell nucleus. In cultured fibroblasts,
GKLF mRNA is found in high levels in growth-arrested cells and is nearly undetectable in …