[HTML][HTML] Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease

EJ van Beers, MCL Schaap, RJ Berckmans… - …, 2009 - ncbi.nlm.nih.gov
EJ van Beers, MCL Schaap, RJ Berckmans, R Nieuwland, A Sturk, FF van Doormaal…
haematologica, 2009ncbi.nlm.nih.gov
Background Sickle cell disease is characterized by a hypercoagulable state as a result of
multiple factors, including chronic hemolysis and circulating cell-derived microparticles.
There is still no consensus on the cellular origin of such microparticles and the exact
mechanism by which they may enhance coagulation activation in sickle cell disease.
Background
Sickle cell disease is characterized by a hypercoagulable state as a result of multiple factors, including chronic hemolysis and circulating cell-derived microparticles. There is still no consensus on the cellular origin of such microparticles and the exact mechanism by which they may enhance coagulation activation in sickle cell disease.
ncbi.nlm.nih.gov