Whereas a significant role for intestinal microbiota in affecting the pathogenesis and
progression of chronic hepatic diseases is well documented, the contribution of the intestinal
flora to acute liver injury has not been extensively addressed. Elucidating the influence of
the intestinal microbiota on acute liver inflammation would be important for better
understanding the transition from acute injury to chronic liver disease. Using the
Concanavalin A (ConA)-induced liver injury model in laboratory mice, we show that the …