Sepsis-induced acute kidney injury revisited: pathophysiology, prevention and future therapies
An understanding of the pathologic mechanisms of sepsis-induced AKI emphasizes the
important role of maladaptive responses to the septic insult. Preventive and therapeutic
measures should be based on counteracting these maladaptive responses of tubular
epithelial cells, inflammation, and microvascular dysfunction.
important role of maladaptive responses to the septic insult. Preventive and therapeutic
measures should be based on counteracting these maladaptive responses of tubular
epithelial cells, inflammation, and microvascular dysfunction.
Summary
An understanding of the pathologic mechanisms of sepsis-induced AKI emphasizes the important role of maladaptive responses to the septic insult. Preventive and therapeutic measures should be based on counteracting these maladaptive responses of tubular epithelial cells, inflammation, and microvascular dysfunction.
Lippincott Williams & Wilkins