Therapeutic targeting of the mitochondrial dysfunction in septic acute kidney injury
SM Parikh - Current opinion in critical care, 2013 - journals.lww.com
Current opinion in critical care, 2013•journals.lww.com
Recent findings from human and experimental septic AKI studies strongly implicate the
mitochondrion as an important target for sublethal kidney injury. Stimulating the natural
pathways through which mitochondrial function is normally recovered following sepsis
represents a promising strategy for the development of novel therapies.
mitochondrion as an important target for sublethal kidney injury. Stimulating the natural
pathways through which mitochondrial function is normally recovered following sepsis
represents a promising strategy for the development of novel therapies.
Summary
Recent findings from human and experimental septic AKI studies strongly implicate the mitochondrion as an important target for sublethal kidney injury. Stimulating the natural pathways through which mitochondrial function is normally recovered following sepsis represents a promising strategy for the development of novel therapies.
Lippincott Williams & Wilkins