MicroRNA-155 is essential for TH2-mediated allergen-induced eosinophilic inflammation in the lung
C Malmhäll, S Alawieh, Y Lu, M Sjöstrand… - Journal of Allergy and …, 2014 - Elsevier
Background Allergic asthma is a chronic disease of the conducting airways characterized by
TH 2 inflammation and tissue remodeling after exposure to inhaled allergens. Although the
TH 2 profile is undisputed, the underlying molecular mechanisms leading to this abnormal
TH 2 profile remain largely unclear. MicroRNAs (miRNAs) are short noncoding RNAs that
are important regulators of gene expression in the immune system. However, the role of
miRNAs, specifically miR-155, in the regulation of allergic airway inflammation is …
TH 2 inflammation and tissue remodeling after exposure to inhaled allergens. Although the
TH 2 profile is undisputed, the underlying molecular mechanisms leading to this abnormal
TH 2 profile remain largely unclear. MicroRNAs (miRNAs) are short noncoding RNAs that
are important regulators of gene expression in the immune system. However, the role of
miRNAs, specifically miR-155, in the regulation of allergic airway inflammation is …