Biologic therapies for autoimmune and connective tissue diseases
RM Wolfe, DC Ang - Immunology and Allergy Clinics, 2017 - immunology.theclinics.com
Biologic therapy continues to revolutionize the treatment of autoimmune disease, especially
in rheumatology. As the understanding of inflammation and autoimmune disease improves,
new targets for therapy emerge. 1 Tumor necrosis factor (TNF)–alpha, interleukin (IL)-1, IL-6,
as well as activated T cell and B cells have all been implicated in the pathophysiology of
rheumatic diseases and have provided potential targets for therapy. New therapies continue
to come to market at a rapid pace, with the most recent US Food and Drug Administration …
in rheumatology. As the understanding of inflammation and autoimmune disease improves,
new targets for therapy emerge. 1 Tumor necrosis factor (TNF)–alpha, interleukin (IL)-1, IL-6,
as well as activated T cell and B cells have all been implicated in the pathophysiology of
rheumatic diseases and have provided potential targets for therapy. New therapies continue
to come to market at a rapid pace, with the most recent US Food and Drug Administration …