To determine the extent and microanatomical distribution of extramyocellular adipocytes
associated with skeletal muscle, histological, biochemical, nuclear magnetic resonance
proton spectroscopic and microcomputed tomography techniques were employed to
analyze skeletal muscle samples from lean and obese Sprague-Dawley rats. Significant
amounts of extramyocellular adipocytes were found on the exterior surface of rat
gastrocnemius, soleus, and tibialis anterior muscles. The triglyceride content of these …