Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways
GJ Braunstahl, SE Overbeek, A KleinJan… - Journal of Allergy and …, 2001 - Elsevier
Background: Allergic rhinitis (AR) and asthma are characterized by means of a similar
inflammatory process in which eosinophils are important effector cells. The migration of
eosinophils from the blood into the tissues is dependent on adhesion molecules. Objective:
To analyze the aspects of nasobronchial cross-talk, we studied the expression of adhesion
molecules in nasal and bronchial mucosa after nasal allergen provocation (NP). Methods:
Nine nonasthmatic subjects with seasonal AR and 9 healthy control subjects underwent NP …
inflammatory process in which eosinophils are important effector cells. The migration of
eosinophils from the blood into the tissues is dependent on adhesion molecules. Objective:
To analyze the aspects of nasobronchial cross-talk, we studied the expression of adhesion
molecules in nasal and bronchial mucosa after nasal allergen provocation (NP). Methods:
Nine nonasthmatic subjects with seasonal AR and 9 healthy control subjects underwent NP …