A phase II randomized placebo-controlled trial of omega-3 fatty acids for the treatment of acute lung injury
RD Stapleton, TR Martin, NS Weiss… - Critical care …, 2011 - journals.lww.com
Objectives: Administration of eicosapentaenoic acid and docosahexanoic acid, omega-3
fatty acids in fish oil, has been associated with improved patient outcomes in acute lung
injury when studied in a commercial enteral formula. However, fish oil has not been tested
independently in acute lung injury. We therefore sought to determine whether enteral fish oil
alone would reduce pulmonary and systemic inflammation in patients with acute lung injury.
Design: Phase II randomized controlled trial. Setting: Five North American medical centers …
fatty acids in fish oil, has been associated with improved patient outcomes in acute lung
injury when studied in a commercial enteral formula. However, fish oil has not been tested
independently in acute lung injury. We therefore sought to determine whether enteral fish oil
alone would reduce pulmonary and systemic inflammation in patients with acute lung injury.
Design: Phase II randomized controlled trial. Setting: Five North American medical centers …