Mechanisms involved in Jurkat cell death induced by oleic and linoleic acids
MF Cury-Boaventura, CC Kanunfre, R Gorjão… - Clinical Nutrition, 2006 - Elsevier
BACKGROUND & AIMS: Previous study from our laboratory showed the toxicity of oleic (OA)
and linoleic acids (LA) on Jurkat and Raji cells and human lymphocytes in vitro. The
mechanisms involved in the toxicity induced by OA and LA on Jurkat cells were determined
in vitro. METHODS: Jurkat cells were treated in the presence of OA and LA (25, 50, 100 and
200μM). The parameters investigated were: triglycerides and cholesterol ester
concentrations determined by enzymatic assay, activation of peroxisome proliferator …
and linoleic acids (LA) on Jurkat and Raji cells and human lymphocytes in vitro. The
mechanisms involved in the toxicity induced by OA and LA on Jurkat cells were determined
in vitro. METHODS: Jurkat cells were treated in the presence of OA and LA (25, 50, 100 and
200μM). The parameters investigated were: triglycerides and cholesterol ester
concentrations determined by enzymatic assay, activation of peroxisome proliferator …