Women with preterm birth have a distinct cervicovaginal metabolome
J Ghartey, JA Bastek, AG Brown, L Anglim… - American journal of …, 2015 - Elsevier
Objective Metabolomics has the potential to reveal novel pathways involved in the
pathogenesis of preterm birth (PTB). The objective of this study was to investigate whether
the cervicovaginal (CV) metabolome was different in asymptomatic women destined to have
a PTB compared with term birth. Study Design A nested case-control study was performed
using CV fluid collected from a larger prospective cohort. The CV fluid was collected
between 20-24 weeks (V1) and 24-28 weeks (V2). The metabolome was compared between …
pathogenesis of preterm birth (PTB). The objective of this study was to investigate whether
the cervicovaginal (CV) metabolome was different in asymptomatic women destined to have
a PTB compared with term birth. Study Design A nested case-control study was performed
using CV fluid collected from a larger prospective cohort. The CV fluid was collected
between 20-24 weeks (V1) and 24-28 weeks (V2). The metabolome was compared between …