The proactive wet-wrap method with diluted corticosteroids versus emollients in children with atopic dermatitis: a prospective, randomized, double-blind, placebo …

SR Janmohamed, AP Oranje, AC Devillers… - Journal of the American …, 2014 - Elsevier
Background Wet-wrap treatment (WWT) has been advocated as a relatively effective
treatment in children with severe atopic dermatitis (AD). WWT often serves as crisis
intervention for AD. Objectives We sought to evaluate the use of WWT with diluted
corticosteroids in comparison with emollient in children with severe AD during 4 weeks in a
proactive schedule during which the frequency of corticosteroid applications was tapered.
Methods A randomized, double-blind, placebo-controlled study was performed in children …