Pharmacological treatments able to activate natriuretic receptors (NPRs) and inhibit cardiac
remodelling in heart failure (HF) patients, are currently under investigation. To better
understand the therapeutic potential of the NPRs activation is necessary to dispose of
experimental models devoid of confounding effects. The pig constitutes an animal model
largely used but its genome is not completely sequenced. Aims of this study were to
sequence NPR-A and NPR-C in Susscrofa and to evaluate ANP, BNP and NPRs mRNA …