Gene expression studies in eosinophilic esophagitis support an immune-mediated etiology
associated with differential regulation of inflammatory and epithelial-derived genes. We
aimed to further characterize epithelial gene expression alterations in eosinophilic
esophagitis and to explore the use of immunohistochemistry to identify these alterations.
Esophageal biopsies from pediatric patients with eosinophilic esophagitis before and after
therapy with topical steroids (N= 7) were screened by gene expression microarray and …