Harnessing the power of the immune system to target cancer
G Lizée, WW Overwijk, L Radvanyi, J Gao… - Annual review of …, 2013 - annualreviews.org
For many years, immunotherapeutic approaches for cancer held more promise than actual
clinical benefit for the majority of patients. However, several recent key advances in tumor
immunology have now turned the tide in favor of immunotherapy for the treatment of many
different cancer types. In this review, we describe four of the most effective
immunotherapeutic approaches currently used in the clinic: cancer vaccines,
immunostimulatory agents, adoptive T cell therapy, and immune checkpoint blockade. In …
clinical benefit for the majority of patients. However, several recent key advances in tumor
immunology have now turned the tide in favor of immunotherapy for the treatment of many
different cancer types. In this review, we describe four of the most effective
immunotherapeutic approaches currently used in the clinic: cancer vaccines,
immunostimulatory agents, adoptive T cell therapy, and immune checkpoint blockade. In …