Background & Aims The gut microbiome is altered in cirrhosis; however its evolution with
disease progression is only partly understood. We aimed to study changes in the
microbiome over cirrhosis severity, its stability over time and its longitudinal alterations with
decompensation. Methods Controls and age-matched cirrhotics (compensated/
decompensated/hospitalized) were included. Their stool microbiota was quantified using
multi-tagged pyrosequencing. The ratio of autochthonous to non-autochthonous taxa was …