Plasma cell disorders form a spectrum ranging from the asymptomatic presence of small
monoclonal populations of plasma cells to conditions like plasma cell leukemia and multiple
myeloma, in which the bone marrow can be replaced by the accumulation of neoplastic
plasma cells. Immunophenotyping has become an invaluable tool in the management of
hematological malignancies and is increasingly finding a role in the diagnosis and
monitoring of plasma cell disorders. Multiparameter flow cytometry has evolved considerably …