[HTML][HTML] Updating the MISEV minimal requirements for extracellular vesicle studies: building bridges to reproducibility

KW Witwer, C Soekmadji, AF Hill… - Journal of …, 2017 - Taylor & Francis
KW Witwer, C Soekmadji, AF Hill, MH Wauben, EI Buzás, D Di Vizio, JM Falcon-Perez
Journal of extracellular vesicles, 2017Taylor & Francis
An editorial describing “minimal experimental requirements for definition of extracellular
vesicles (EVs)”, or more simply “minimal information for studies of EVs (MISEV)” was
published in the Journal of Extracellular Vesicles in late 2014 [1]. Similar to guidelines in
other scientific fields [2–4],“MISEV2014”, as we will call it here, provided recommendations
on experimental methods and minimal information in reporting. Specifically, three key areas
were addressed: EV isolation/purification, EV characterization and EV functional studies …
An editorial describing “minimal experimental requirements for definition of extracellular vesicles (EVs)”, or more simply “minimal information for studies of EVs (MISEV)” was published in the Journal of Extracellular Vesicles in late 2014 [1]. Similar to guidelines in other scientific fields [2–4],“MISEV2014”, as we will call it here, provided recommendations on experimental methods and minimal information in reporting. Specifically, three key areas were addressed: EV isolation/purification, EV characterization and EV functional studies (see Text Box 1).
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