Growth hormone neurosecretory dysfunction: a treatable cause of short stature

BE Spiliotis, GP August, W Hung, W Sonis… - Jama, 1984 - jamanetwork.com
Pulsatile growth hormone (GH) secretion was assessed in a subgroup of short children to
determine whether they had GH secretory abnormalities, and these results were compared
with those of normal and GH-deficient children. This subgroup of children was defined as
having GH neurosecretory dysfunction and met the following criteria: height, less than first
percentile; growth velocity, 4 cm/yr or less; bone age, two or more years behind
chronological age, normal findings from provocative GH tests (peak,≥ 10 ng/mL), low …