The cardiac fibroblast: Origin, identity and role in homeostasis and disease
MB Furtado, MW Costa, NA Rosenthal - Differentiation, 2016 - Elsevier
The mammalian heart is responsible for supplying blood to two separate circulation circuits
in a parallel manner. This design provides efficient oxygenation and nutrients to the whole
body through the left-sided pump, while the right-sided pump delivers blood to the
pulmonary circulation for re-oxygenation. In order to achieve this demanding job, the
mammalian heart evolved into a highly specialised organ comprised of working contractile
cells or cardiomyocytes, a directional and insulated conduction system, capable of …
in a parallel manner. This design provides efficient oxygenation and nutrients to the whole
body through the left-sided pump, while the right-sided pump delivers blood to the
pulmonary circulation for re-oxygenation. In order to achieve this demanding job, the
mammalian heart evolved into a highly specialised organ comprised of working contractile
cells or cardiomyocytes, a directional and insulated conduction system, capable of …
