Polycystic ovary syndrome: understanding the role of the brain
AM Moore, RE Campbell - Frontiers in neuroendocrinology, 2017 - Elsevier
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder and the leading cause
of anovulatory infertility. Characterised by hyperandrogenism, menstrual dysfunction and
polycystic ovaries, PCOS is a broad-spectrum disorder unlikely to stem from a single
common origin. Although commonly considered an ovarian disease, the brain is now a
prime suspect in both the ontogeny and pathology of PCOS. We discuss here the
neuroendocrine impairments present in PCOS that implicate involvement of the brain and …
of anovulatory infertility. Characterised by hyperandrogenism, menstrual dysfunction and
polycystic ovaries, PCOS is a broad-spectrum disorder unlikely to stem from a single
common origin. Although commonly considered an ovarian disease, the brain is now a
prime suspect in both the ontogeny and pathology of PCOS. We discuss here the
neuroendocrine impairments present in PCOS that implicate involvement of the brain and …
