Aortic stiffness, blood pressure progression, and incident hypertension

BM Kaess, J Rong, MG Larson, NM Hamburg, JA Vita… - Jama, 2012 - jamanetwork.com
Context Vascular stiffness increases with advancing age and is a major risk factor for age-
related morbidity and mortality. Vascular stiffness and blood pressure pulsatility are related;
however, temporal relationships between vascular stiffening and blood pressure elevation
have not been fully delineated. Objective To examine temporal relationships among
vascular stiffness, central hemodynamics, microvascular function, and blood pressure
progression. Design, Setting, and Participants Longitudinal community-based cohort study …