ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain
RPT Somerville, JM Longpré, ED Apel, RM Lewis… - Journal of Biological …, 2004 - jbc.org
We have characterized ADAMTS7B, the authentic full-length protein product of the
ADAMTS7 gene. ADAMTS7B has a domain organization similar to that of ADAMTS12, with a
total of eight thrombospondin type 1 repeats in its ancillary domain. Of these, seven are
arranged in two distinct clusters that are separated by a mucin domain. Unique to the
ADAMTS family, ADAMTS7B is modified by attachment of the glycosaminoglycan
chondroitin sulfate within the mucin domain, thus rendering it a proteoglycan …
ADAMTS7 gene. ADAMTS7B has a domain organization similar to that of ADAMTS12, with a
total of eight thrombospondin type 1 repeats in its ancillary domain. Of these, seven are
arranged in two distinct clusters that are separated by a mucin domain. Unique to the
ADAMTS family, ADAMTS7B is modified by attachment of the glycosaminoglycan
chondroitin sulfate within the mucin domain, thus rendering it a proteoglycan …
